Werewolf Therapeutics, Inc. (HOWL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

45,804,042Shares Outstanding

14,769,344Shares held by institutions

$13,580,412Value of institutional holdings

32.24%Institutional ownership %

-17.58%Shares Changed QoQ

51No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Werewolf Therapeutics, Inc. (NASDAQ:HOWL) has 51 institutional investors with active 13F positions as of December 2025.

These investors collectively held 32.2% of Werewolf Therapeutics's outstanding shares in December 2025, down from 50.1% in September 2025.
They decreased total shares held in Werewolf Therapeutics by -17.45% from last quarter, and the number of investors in HOWL decreased 31.08% annually.
Among the 51 funds, 20 bought more Werewolf Therapeutics shares, 19 sold down, and 12 held their ground.
Combined, these investors held 14.74Mn shares in HOWL for December 2025, down by 3.12Mn shares quarter on quarter, and down 13.72Mn shares year over year.
As of December 31, 2025, the biggest holder of Werewolf Therapeutics is RA CAPITAL MANAGEMENT, L.P. at 6.68Mn shares, representing 14.59% of shares outstanding.
The largest buyers of Werewolf Therapeutics for the quarter ending December 2025 were Lynx1 Capital Management LP (655.93K), RENAISSANCE TECHNOLOGIES LLC (221.77K), UBS Group AG (47.93K), Morgan Stanley (26.75K), Regal Investment Advisors LLC (25.39K).
Top sellers of HOWL stock for the quarter ending December 2025 included Bank Of America Corp /De/ (2.92Mn), MPM BioImpact LLC (1.02Mn), JANE STREET GROUP, LLC (111.26K), MILLENNIUM MANAGEMENT LLC (76.94K), Barclays Plc (68.12K).
Werewolf Therapeutics's 10 largest shareholders as of December 2025 include RA CAPITAL MANAGEMENT, L.P. (6.68Mn), VANGUARD GROUP INC (1.41Mn), MPM BioImpact LLC (1.39Mn), Bank Of America Corp /De/ (737.55K), RENAISSANCE TECHNOLOGIES LLC (677.77K), Lynx1 Capital Management LP (655.93K), SPHERA FUNDS MANAGEMENT LTD. (626.81K), DC Funds, LP (589.1K), GEODE CAPITAL MANAGEMENT, LLC (335.89K), MILLENNIUM MANAGEMENT LLC (240.11K) per Business Quant data.

51 Institutional Holders

14,769,344 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	6,681,307	0	0.00%	$4,232,608.00
VANGUARD GROUP INC	31 Dec, 2025	1,408,047	0	0.00%	$892,702.00
MPM BioImpact LLC	31 Dec, 2025	1,393,557	-1,015,253	-42.15%	$883,515.00
Bank Of America Corp /De/	31 Dec, 2025	737,550	-2,923,034	-79.85%	$466,869.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	677,766	221,766	48.63%	$429,365.00
Lynx1 Capital Management LP	31 Dec, 2025	655,926	655,926	0.00%	$415,529.00
SPHERA FUNDS MANAGEMENT LTD.	31 Dec, 2025	626,810	0	0.00%	$397,084.00
DC Funds, LP	31 Dec, 2025	589,102	0	0.00%	$373,196.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	335,886	5,099	1.54%	$212,838.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	240,109	-76,944	-24.27%	$152,109.00
Alyeska Investment Group, L.P.	31 Dec, 2025	235,705	0	0.00%	$149,319.00
JANE STREET GROUP, LLC	31 Dec, 2025	157,322	-111,255	-41.42%	$99,663.00
State Street Corp	31 Dec, 2025	119,168	0	0.00%	$75,493.00
BlackRock, Inc.	31 Dec, 2025	101,643	320	0.32%	$64,391.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	99,829	6,788	7.30%	$63,242.00
Northern Trust Corp	31 Dec, 2025	86,851	21,015	31.92%	$55,020.00
BRIDGEWAY CAPITAL MANAGEMENT, LLC	31 Dec, 2025	77,000	-25,000	-24.51%	$48,780.00
Goldman Sachs Group Inc	31 Dec, 2025	68,146	7,805	12.93%	$43,170.00
UBS Group AG	31 Dec, 2025	60,708	47,932	375.17%	$38,428.00
Vontobel Holding Ltd.	31 Dec, 2025	60,003	24,003	66.68%	$38,012.00

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