Gain Therapeutics, Inc. (GANX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

35,229,153Shares Outstanding

651,014Shares held by institutions

$1,178,335Value of institutional holdings

22.76%Institutional ownership %

119.72%Shares Changed QoQ

45No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Gain Therapeutics, Inc. (NASDAQ:GANX) includes 45 filers as of the latest reporting cycle ending December 2025.

The percentage of Gain Therapeutics owned by institutions changed from 12.1% in September 2025 to 22.8% in December 2025, marking a slight up trend.
On a quarter-over-quarter basis, institutional holdings shifted by 119.72%, with a year-over-year an increase of 80.00% in the count of filers.
A review of institutional activity for Gain Therapeutics shows 36 of 45 filers increasing their positions, while 3 reduced their stake, and 6 remained unchanged.
The total number of shares held by institutions in Gain Therapeutics increased to 8.02Mn as of December 2025, a net change of up by 4.37Mn shares quarter on quarter, and up 6.05Mn shares year over year.
MARSHALL WACE, LLP's holding of 1.66Mn shares as of December 31, 2025 makes it the primary institutional investor in Gain Therapeutics, owning 4.72% of the stock.
Among the most significant buyers of Gain Therapeutics during December 2025 were MARSHALL WACE, LLP (1.49Mn), Potomac Capital Management, Inc. (1.01Mn), SUSQUEHANNA INTERNATIONAL GROUP, LLP (603.91K), Cambridge Investment Research Advisors, Inc. (250.00K), JANE STREET GROUP, LLC (169.88K).
Leading sellers of Gain Therapeutics stock in December 2025 included RENAISSANCE TECHNOLOGIES LLC (108.70K), UBS Group AG (59.56K), MORGAN STANLEY (8.08K).
The top 10 institutional holders of Gain Therapeutics for the quarter ending December 2025 included MARSHALL WACE, LLP (1.66Mn), Potomac Capital Management, Inc. (1.01Mn), JONES FINANCIAL COMPANIES LLLP (702.21K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (684.35K), VANGUARD GROUP INC (569.90K), Cambridge Investment Research Advisors, Inc. (568.64K), DME Capital Management, LP (566.13K), GEODE CAPITAL MANAGEMENT, LLC (397.94K), JANE STREET GROUP, LLC (242.33K), BlackRock, Inc. (209.58K).

45 Institutional Holders

651,014 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
MARSHALL WACE, LLP	31 Dec, 2025	1,662,293	1,487,186	849.30%	$5,352,582.00
Potomac Capital Management, Inc.	31 Dec, 2025	1,010,000	1,010,000	0.00%	$3,252,200.00
JONES FINANCIAL COMPANIES LLLP	31 Dec, 2025	702,213	25,391	3.75%	$2,261,126.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	684,349	603,914	750.81%	$2,203,604.00
VANGUARD GROUP INC	31 Dec, 2025	569,901	35,549	6.65%	$1,835,082.00
Cambridge Investment Research Advisors, Inc.	31 Dec, 2025	568,645	250,000	78.46%	$1,831.00
DME Capital Management, LP	31 Dec, 2025	566,130	0	0.00%	$1,822,939.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	397,942	53,796	15.63%	$1,282,455.00
JANE STREET GROUP, LLC	31 Dec, 2025	242,328	169,878	234.48%	$780,296.00
BlackRock, Inc.	31 Dec, 2025	209,579	93,395	80.39%	$674,844.00
Cresset Asset Management, LLC	31 Dec, 2025	160,000	160,000	0.00%	$515,200.00
STATE STREET CORP	31 Dec, 2025	157,537	66,400	72.86%	$507,269.00
MORGAN STANLEY	31 Dec, 2025	147,591	-8,084	-5.19%	$475,244.00
LPL Financial LLC	31 Dec, 2025	106,550	106,550	0.00%	$343,091.00
NORTHERN TRUST CORP	31 Dec, 2025	102,001	13,602	15.39%	$328,443.00
UBS Group AG	31 Dec, 2025	81,121	-59,556	-42.34%	$261,210.00
Focus Partners Wealth	31 Dec, 2025	77,855	77,855	0.00%	$250,693.00
HRT FINANCIAL LP	31 Dec, 2025	55,679	35,962	182.39%	$179.00
GROUP ONE TRADING LLC	31 Dec, 2025	54,159	37,384	222.86%	$174,392.00
SIMPLEX TRADING, LLC	31 Dec, 2025	47,946	47,946	0.00%	$154,386.00

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