4D Molecular Therapeutics, Inc. (FDMT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

55,780,533Shares Outstanding

5,019,397Shares held by institutions

$47,583,884Value of institutional holdings

93.66%Institutional ownership %

35.54%Shares Changed QoQ

145No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 145 institutional investors hold a position in 4D Molecular Therapeutics, Inc. (NASDAQ:FDMT).

Institutional ownership in 4D Molecular Therapeutics edged up to 93.7% in December 2025, compared to 70.9% in September 2025.
Quarterly data indicates a 35.54% shift in institutional share volume, and the annual owner count reflects a decrease of 2.03%.
The latest 13F cycle for 4D Molecular Therapeutics reveals that of 145 total investors, 84 funds grew their exposure, whereas 36 reduced theirs and 25 made no changes.
This class of investors increased its holdings in 4D Molecular Therapeutics to 52.25Mn shares for the 13F-cycle ending December 2025, up by 13.70Mn shares quarter on quarter, and up 5.40Mn shares year over year.
As of December 31, 2025, RA CAPITAL MANAGEMENT, L.P. held 4D Molecular Therapeutics's largest shareholding position with over 5.65Mn shares, representing 10.13% of total outstanding shares.
Among the most significant buyers of 4D Molecular Therapeutics during December 2025 were JANUS HENDERSON GROUP PLC (2.88Mn), STATE STREET CORP (1.79Mn), Novo Holdings A/S (1.65Mn), Point72 Asset Management, L.P. (1.54Mn), RA CAPITAL MANAGEMENT, L.P. (1.09Mn).
Leading sellers of 4D Molecular Therapeutics stock in December 2025 included MILLENNIUM MANAGEMENT LLC (1.05Mn), Assenagon Asset Management S.A. (367.46K), TWO SIGMA ADVISERS, LP (274.40K), JPMORGAN CHASE & CO (234.01K), ROYAL BANK OF CANADA (169.85K).
The top 10 institutional holders of 4D Molecular Therapeutics for the quarter ending December 2025 included RA CAPITAL MANAGEMENT, L.P. (5.65Mn), JANUS HENDERSON GROUP PLC (4.64Mn), BVF INC/IL (4.63Mn), GOLDMAN SACHS GROUP INC (4.30Mn), BlackRock, Inc. (4.06Mn), Novo Holdings A/S (3.65Mn), VANGUARD GROUP INC (3.09Mn), STATE STREET CORP (2.69Mn), ARMISTICE CAPITAL, LLC (1.94Mn), FEDERATED HERMES, INC. (1.61Mn).

145 Institutional Holders

5,019,397 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	5,653,211	1,090,000	23.89%	$42,399,083.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	4,635,875	2,882,508	164.40%	$34,726,165.00
BVF INC/IL	31 Dec, 2025	4,629,289	0	0.00%	$34,719,668.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	4,302,905	174,489	4.23%	$32,271,789.00
BlackRock, Inc.	31 Dec, 2025	4,064,876	195,746	5.06%	$30,486,573.00
Novo Holdings A/S	31 Dec, 2025	3,650,737	1,650,737	82.54%	$27,380,528.00
VANGUARD GROUP INC	31 Dec, 2025	3,093,527	518,405	20.13%	$23,201,453.00
STATE STREET CORP	31 Dec, 2025	2,688,880	1,785,106	197.52%	$20,166,600.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	1,936,000	840,000	76.64%	$14,520,000.00
FEDERATED HERMES, INC.	31 Dec, 2025	1,609,482	14,650	0.92%	$12,071,116.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,539,860	1,539,860	0.00%	$11,548,950.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,235,156	1,060,156	605.80%	$9,263,670.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,012,025	98,506	10.78%	$7,591,665.00
Evergreen Quality Fund GP, Ltd.	31 Dec, 2025	951,474	951,474	0.00%	$7,136,055.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	832,591	13,325	1.63%	$6,244,433.00
DEUTSCHE BANK AG\	31 Dec, 2025	704,207	160,876	29.61%	$5,281,553.00
MORGAN STANLEY	31 Dec, 2025	672,695	-163,216	-19.53%	$5,045,215.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	512,900	199,714	63.77%	$3,846,750.00
ArrowMark Colorado Holdings LLC	31 Dec, 2025	485,389	-18,726	-3.71%	$3,640,418.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	475,737	475,737	0.00%	$3,568,028.00

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