As of August 04, 2026, the three largest insider holders of EYPT are Asset Management, Lp Cormorant (TenPercentOwner, 8.32Mn shares), Asset Management, Lp Cormorant (Other, 8.27Mn shares), Healthcare Partners, L.P. Ew (TenPercentOwner, 7.14Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Asset Management, Lp Cormorant | Other | 0 | 8,265,000 | 8,265,000 | 51.3% | 08 Dec, 2025 |
| 2 | Healthcare Partners, L.P. Ew | TenPercentOwner, Other | 0 | 7,141,313 | 7,141,313 | 44.3% | 06 Sep, 2023 |
| 3 | Jay S. Duker | President And Ceo | 986 | 177,431 | 178,417 | 1.1% | 24 Mar, 2026 |
| 4 | George Elston | Chief Financial Officer | 87,818 | 30,000 | 117,818 | 0.7% | 06 Mar, 2026 |
| 5 | Therapeutics Ocumension | Director | 100,221 | 0 | 100,221 | 0.6% | 16 Jan, 2024 |
| 6 | Ye Liu | Director | 0 | 100,221 | 100,221 | 0.6% | 16 Jan, 2024 |
| 7 | Dario A. Paggiarino | Chief Medical Officer | 67,080 | 0 | 67,080 | 0.4% | 02 Apr, 2024 |
| 8 | David Scott Jones | Svp Chief Commercial Officer | 44,916 | 0 | 44,916 | 0.3% | 13 Feb, 2024 |
| 9 | Karen L. Zaderej | Director | 38,500 | 0 | 38,500 | 0.2% | 11 Jul, 2025 |
| 10 | John B. Landis | Director | 21,400 | 0 | 21,400 | 0.1% | 07 Jan, 2025 |
| 11 | Michael Craig Pine | Chief Corp Dev.Strat. Officer | 13,662 | 0 | 13,662 | 0.1% | 09 Jan, 2024 |
| 12 | Goran Ando | Director | 13,150 | 0 | 13,150 | 0.1% | 21 Aug, 2024 |
| 13 | Wendy F Dicicco | Director | 9,967 | 0 | 9,967 | 0.1% | 21 Aug, 2024 |
| 14 | Anthony P Adamis | Director | 4,000 | 0 | 4,000 | 0.0% | 25 Jun, 2024 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 17 Apr, 2026 | Ramiro Ribeiro | Chief Medical Officer | Acquired M | 2,437 | $8.26 | $20.13K | 2,437 | Direct |
| 17 Apr, 2026 | Ramiro Ribeiro | Chief Medical Officer | Disposed S | 2,437 | $15.00 | $36.56K | 0 | Direct |
| 17 Apr, 2026 | Ramiro Ribeiro | Chief Medical Officer | Disposed M | 2,437 | $0.00 | $0 | 80,438 | Direct |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Disposed J | 76,766 | $13.11 | $1.01Mn | 986 | Direct |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Acquired J | 76,766 | $13.11 | $1.01Mn | 177,431 | Indirect |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Disposed J | 52,500 | $8.75 | $459.38K | 7,800 | Direct |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Acquired J | 52,500 | $8.75 | $459.38K | 52,500 | Indirect |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Disposed J | 97,500 | $9.57 | $933.08K | 82,500 | Direct |
| 23 Mar, 2026 | Jay S. Duker | President And Ceo | Acquired J | 97,500 | $9.57 | $933.08K | 97,500 | Indirect |
| 16 Mar, 2026 | Jay S. Duker | President And Ceo | Acquired P | 1,500 | $13.15 | $19.72K | 100,665 | Indirect |
| 02 Mar, 2026 | George Elston | Chief Financial Officer | Disposed G | 5,000 | $0.00 | $0 | 87,818 | Direct |
| 02 Mar, 2026 | George Elston | Chief Financial Officer | Acquired G | 5,000 | $0.00 | $0 | 30,000 | Indirect |
| 06 Jan, 2026 | George Elston | Chief Financial Officer | Acquired M | 15,285 | $0.00 | $0 | 96,339 | Direct |
| 06 Jan, 2026 | Jay S. Duker | President And Ceo | Acquired M | 20,793 | $0.00 | $0 | 87,806 | Direct |
| 06 Jan, 2026 | George Elston | Chief Financial Officer | Disposed F | 4,487 | $16.86 | $75.65K | 91,852 | Direct |
| 06 Jan, 2026 | Jay S. Duker | President And Ceo | Disposed F | 10,054 | $16.86 | $169.51K | 77,752 | Direct |
| 06 Jan, 2026 | Jay S. Duker | President And Ceo | Disposed M | 20,793 | $0.00 | $0 | 0 | Direct |
| 06 Jan, 2026 | George Elston | Chief Financial Officer | Disposed M | 15,285 | $0.00 | $0 | 0 | Direct |
| 02 Jan, 2026 | Reginald J. Sanders | Director | Acquired A | 40,000 | $0.00 | $0 | 40,000 | Direct |
| 02 Jan, 2026 | John B. Landis | Director | Acquired A | 40,000 | $0.00 | $0 | 40,000 | Direct |