Eton Pharmaceuticals, Inc. (ETON) Institutional Ownership

Institutions by Trading Activity

26,893,000Shares Outstanding

19,099,708Shares held by institutions

$572,991,240Value of institutional holdings

71.02%Institutional ownership %

10.94%Shares Changed QoQ

101No. of institutional investors

Eton Pharmaceuticals, Inc. (NASDAQ:ETON) showed up in the 13F filings of 101 institutional investors as of December 2025.

These investors collectively held 59.7% of Eton Pharmaceuticals's outstanding shares in December 2025, down from 67.3% in September 2025.
Their total shares held in ETON decreased -6.61% from the prior quarter, while the number of investors in Eton Pharmaceuticals increased 42.25% year over year.
Of these 101 funds, 48 grew their exposure to Eton Pharmaceuticals, 37 cut back, and 16 maintained positions.
The aggregate institutional position in Eton Pharmaceuticals amounted to 16.04Mn shares as of December 2025, down by 1.14Mn shares quarter on quarter, and up 2.86Mn shares year over year.
As of December 31, 2025, the biggest holder of Eton Pharmaceuticals is JUNCTURE WEALTH STRATEGIES, LLC at 19.18K shares, representing 0.07% of shares outstanding.
Leading buyers of Eton Pharmaceuticals shares for the quarter ending December 2025 were JUNCTURE WEALTH STRATEGIES, LLC (185), GF FUND MANAGEMENT CO. LTD. (70).
The largest sales of ETON for the quarter ending December 2025 came from Farther Finance Advisors, LLC (23), GAMMA Investing LLC (2).
Eton Pharmaceuticals's 7 largest shareholders as of December 2025 include JUNCTURE WEALTH STRATEGIES, LLC (19.18K), CHICAGO TRUST Co NA (16.7K), State of Alaska, Department of Revenue (6.94K), GF FUND MANAGEMENT CO. LTD. (597), Sterling Capital Management LLC (167), Farther Finance Advisors, LLC (123), GAMMA Investing LLC (21) per Business Quant data.

19,099,708 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Opaleye Management Inc.	31 Dec, 2025	5,720,000	2,860,000	100.00%	$96,725,200.00
EcoR1 Capital, LLC	31 Dec, 2025	2,030,544	0	0.00%	$34,336,499.00
BlackRock, Inc.	31 Dec, 2025	1,738,907	34,546	2.03%	$29,404,917.00
VANGUARD GROUP INC	31 Dec, 2025	1,348,668	4,553	0.34%	$22,805,976.00
Nantahala Capital Management, LLC	31 Dec, 2025	1,175,951	0	0.00%	$19,885,331.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	565,051	-8,979	-1.56%	$9,557,084.00
State Street Corp	31 Dec, 2025	501,925	63,480	14.48%	$8,487,552.00
Morgan Stanley	31 Dec, 2025	493,914	-92,132	-15.72%	$8,352,085.00
Westside Investment Management, Inc.	31 Dec, 2025	470,940	-1,600	-0.34%	$7,963,285.00
OBERWEIS ASSET MANAGEMENT INC/	31 Dec, 2025	431,300	238,940	124.22%	$7,293,283.00
THOMPSON SIEGEL & WALMSLEY LLC	31 Dec, 2025	408,541	-10,025	-2.40%	$6,908.00
Goldman Sachs Group Inc	31 Dec, 2025	392,526	202,362	106.41%	$6,637,614.00
Aristides Capital LLC	31 Dec, 2025	322,872	155,285	92.66%	$5,459,766.00
BNP PARIBAS FINANCIAL MARKETS	31 Dec, 2025	277,458	47,668	20.74%	$4,691,815.00
Northern Trust Corp	31 Dec, 2025	231,849	-13,202	-5.39%	$3,920,566.00
CANNELL CAPITAL LLC	31 Dec, 2025	216,917	-238,488	-52.37%	$3,668,066.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	205,700	-118,921	-36.63%	$3,478,387.00
Diametric Capital, LP	31 Dec, 2025	193,155	93,846	94.50%	$3,266,251.00
Jpmorgan Chase & Co	31 Dec, 2025	185,439	-517,395	-73.62%	$3,135,773.00
Lumbard & Kellner, LLC	31 Dec, 2025	174,944	-1,356	-0.77%	$2,958,303.00

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