As of September 29, 2026, Eton Pharmaceuticals's top three insider holders are Management Inc. Opaleye (TenPercentOwner, 2.71Mn shares), Sean Brynjelsen (President Ceo, 961.19K shares), James R. Gruber (Chief Financial Officer, 213.42K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Management Inc. Opaleye | TenPercentOwner | 0 | 2,705,000 | 2,705,000 | 66.7% | 17 Jul, 2026 |
| 2 | Sean Brynjelsen | President Ceo | 961,194 | 0 | 961,194 | 23.7% | 20 Aug, 2026 |
| 3 | James R. Gruber | Chief Financial Officer | 213,420 | 0 | 213,420 | 5.3% | 14 Jan, 2026 |
| 4 | Paul V Maier | Director | 72,245 | 0 | 72,245 | 1.8% | 31 Aug, 2026 |
| 5 | Norbert G Riedel | Director | 67,155 | 0 | 67,155 | 1.7% | 22 Apr, 2026 |
| 6 | David Krempa | Chief Business Officer | 37,025 | 0 | 37,025 | 0.9% | 24 Aug, 2026 |
| 7 | Ipek Erdogan-Trinkaus | Chief Commercial Officer | 2,403 | 0 | 2,403 | 0.1% | 12 Dec, 2025 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 28 Aug, 2026 | Paul V Maier | Director | Acquired M | 50,000 | $3.78 | $189.00K | 109,745 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 36,387 | $58.64 | $2.13Mn | 73,358 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 13,485 | $60.21 | $811.93K | 59,873 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 128 | $61.77 | $7.91K | 59,745 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Acquired M | 12,500 | $7.31 | $91.38K | 72,245 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed M | 50,000 | $0.00 | $0 | 0 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Acquired M | 12,500 | $0.00 | $0 | 0 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Acquired M | 50,000 | $3.78 | $189.00K | 109,745 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 36,387 | $58.64 | $2.13Mn | 73,358 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 13,485 | $60.21 | $811.93K | 59,873 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed S | 128 | $61.77 | $7.91K | 59,745 | Direct |
| 28 Aug, 2026 | Paul V Maier | Director | Disposed M | 50,000 | $0.00 | $0 | 0 | Direct |
| 24 Aug, 2026 | David Krempa | Chief Business Officer | Acquired M | 25,000 | $7.31 | $182.75K | 62,025 | Direct |
| 24 Aug, 2026 | David Krempa | Chief Business Officer | Disposed S | 25,000 | $65.07 | $1.63Mn | 37,025 | Direct |
| 24 Aug, 2026 | David Krempa | Chief Business Officer | Disposed M | 25,000 | $0.00 | $0 | 70,000 | Direct |
| 19 Aug, 2026 | Sean Brynjelsen | President Ceo | Disposed S | 8,978 | $62.65 | $562.47K | 1,052,216 | Direct |
| 20 Aug, 2026 | Sean Brynjelsen | President Ceo | Disposed S | 47,307 | $60.17 | $2.85Mn | 1,004,909 | Direct |
| 20 Aug, 2026 | Sean Brynjelsen | President Ceo | Disposed S | 36,373 | $61.11 | $2.22Mn | 968,536 | Direct |
| 20 Aug, 2026 | Sean Brynjelsen | President Ceo | Disposed S | 7,342 | $62.12 | $456.09K | 961,194 | Direct |
| 31 Jul, 2026 | Sean Brynjelsen | President Ceo | Acquired A | 128,985 | $0.00 | $0 | 128,985 | Direct |