Cytokinetics Inc (CYTK) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

119,545,946Shares Outstanding

6,550,953Shares held by institutions

$436,424,489Value of institutional holdings

107.94%Institutional ownership %

-4.71%Shares Changed QoQ

403No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 403 institutional investors hold a position in Cytokinetics Inc (NASDAQ:CYTK).

Institutional ownership in Cytokinetics edged down to 107.9% in December 2025, compared to 124.1% in September 2025.
The company experienced a -4.71% quarterly change in institutional shares held, alongside an increase of 17.84% in total owners annually.
A review of institutional activity for Cytokinetics shows 231 of 403 filers increasing their positions, while 125 reduced their stake, and 47 remained unchanged.
The total number of shares held by institutions in Cytokinetics decreased to 129.03Mn as of December 2025, a net change of down by 6.37Mn shares quarter on quarter, and down 3.39Mn shares year over year.
With 16.40Mn shares, BlackRock, Inc. commands the largest institutional position in Cytokinetics as of December 31, 2025, equating to 13.71% of the company.
Among the most significant buyers of Cytokinetics during December 2025 were GOLDMAN SACHS GROUP INC (928.32K), BlackRock, Inc. (869.38K), NORGES BANK (807.07K), WELLINGTON MANAGEMENT GROUP LLP (528.50K), Qube Research & Technologies Ltd (528.24K).
Leading sellers of Cytokinetics stock in December 2025 included T. Rowe Price Investment Management, Inc. (9.69Mn), Deep Track Capital, LP (963.00K), UBS Group AG (671.79K), Aberdeen Group plc (444.77K), Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. (444.50K).
The top 10 institutional holders of Cytokinetics for the quarter ending December 2025 included BlackRock, Inc. (16.40Mn), FMR LLC (12.81Mn), VANGUARD GROUP INC (12.05Mn), T. Rowe Price Investment Management, Inc. (9.39Mn), WELLINGTON MANAGEMENT GROUP LLP (7.94Mn), STATE STREET CORP (5.83Mn), Deep Track Capital, LP (3.34Mn), GEODE CAPITAL MANAGEMENT, LLC (3.06Mn), BANK OF AMERICA CORP /DE/ (2.94Mn), RTW INVESTMENTS, LP (2.72Mn).

403 Institutional Holders

6,550,953 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	16,395,123	869,376	5.60%	$1,041,746,107.00
FMR LLC	31 Dec, 2025	12,807,752	-283,895	-2.17%	$813,804,582.00
VANGUARD GROUP INC	31 Dec, 2025	12,048,131	191,336	1.61%	$765,538,243.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	9,390,404	-9,690,092	-50.79%	$596,667.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	7,937,063	528,502	7.13%	$504,320,984.00
STATE STREET CORP	31 Dec, 2025	5,825,295	207,961	3.70%	$370,139,244.00
Deep Track Capital, LP	31 Dec, 2025	3,336,998	-963,002	-22.40%	$212,032,853.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,056,017	15,815	0.52%	$194,213,741.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	2,941,152	-120,644	-3.94%	$186,880,798.00
RTW INVESTMENTS, LP	31 Dec, 2025	2,721,158	0	0.00%	$172,902,379.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	2,593,047	928,324	55.76%	$164,762,207.00
Polar Capital Holdings Plc	31 Dec, 2025	2,422,612	-360,318	-12.95%	$153,932,766.00
Woodline Partners LP	31 Dec, 2025	1,648,428	703	0.04%	$104,741,115.00
JPMORGAN CHASE & CO	31 Dec, 2025	1,412,797	-130,060	-8.43%	$89,769,121.00
Integral Health Asset Management, LLC	31 Dec, 2025	1,400,000	0	0.00%	$88,956,000.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,383,437	9,554	0.70%	$87,903,587.00
NORTHERN TRUST CORP	31 Dec, 2025	1,380,787	-26,045	-1.85%	$87,735,208.00
MORGAN STANLEY	31 Dec, 2025	1,265,301	-255,885	-16.82%	$80,397,317.00
Capital International Investors	31 Dec, 2025	1,178,780	0	0.00%	$74,899,681.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,178,125	468,425	66.00%	$74,858,062.00

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