CytomX Therapeutics, Inc. (CTMX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

158,100,000Shares Outstanding

43,776,099Shares held by institutions

$230,700,042Value of institutional holdings

89.00%Institutional ownership %

24.89%Shares Changed QoQ

117No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 117 institutional investors hold a position in CytomX Therapeutics, Inc. (NASDAQ:CTMX).

CytomX Therapeutics saw its institutional ownership percentage rose to 89.0% in December 2025 from 87.2% in September 2025.
Institutional share ownership changed by 24.89% QoQ, while the number of institutional owners saw an increase of 69.57% YoY.
The latest 13F cycle for CytomX Therapeutics reveals that of 117 total investors, 74 funds grew their exposure, whereas 24 reduced theirs and 19 made no changes.
Collectively, institutional investors increased their stake in CytomX Therapeutics to 140.71Mn shares as of December 2025, a change that is up by 28.04Mn shares quarter on quarter and up 94.03Mn shares year over year.
As of December 31, 2025, FMR LLC held CytomX Therapeutics's largest shareholding position with over 24.69Mn shares, representing 15.62% of total outstanding shares.
Among the most significant buyers of CytomX Therapeutics during December 2025 were FMR LLC (9.29Mn), Kynam Capital Management, LP (5.32Mn), STATE STREET CORP (4.50Mn), Eversept Partners, LP (2.51Mn), Financial Engines Advisors L.L.C. (2.45Mn).
Leading sellers of CytomX Therapeutics stock in December 2025 included ORBIMED ADVISORS LLC (4.94Mn), CITADEL ADVISORS LLC (1.46Mn), MILLENNIUM MANAGEMENT LLC (1.10Mn), Inspire Investing, LLC (522.47K), VANGUARD GROUP INC (472.22K).
The top 10 institutional holders of CytomX Therapeutics for the quarter ending December 2025 included FMR LLC (24.69Mn), VR Adviser, LLC (15.56Mn), PERCEPTIVE ADVISORS LLC (9.68Mn), Kynam Capital Management, LP (8.97Mn), VANGUARD GROUP INC (8.48Mn), Commodore Capital LP (7.69Mn), Point72 Asset Management, L.P. (5.19Mn), STATE STREET CORP (5.14Mn), ADAR1 Capital Management, LLC (4.28Mn), BAKER BROS. ADVISORS LP (4.25Mn).

117 Institutional Holders

43,776,099 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	24,688,109	9,291,909	60.35%	$105,171,344.00
VR Adviser, LLC	31 Dec, 2025	15,561,500	0	0.00%	$66,291,990.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	9,680,185	0	0.00%	$41,237,588.00
Kynam Capital Management, LP	31 Dec, 2025	8,966,077	5,319,574	145.88%	$38,195,488.00
VANGUARD GROUP INC	31 Dec, 2025	8,475,584	-472,223	-5.28%	$36,105,988.00
Commodore Capital LP	31 Dec, 2025	7,692,300	0	0.00%	$32,769,198.00
Point72 Asset Management, L.P.	31 Dec, 2025	5,189,538	1,120,963	27.55%	$22,107,432.00
STATE STREET CORP	31 Dec, 2025	5,140,931	4,495,949	697.07%	$21,900,366.00
ADAR1 Capital Management, LLC	31 Dec, 2025	4,282,769	237,355	5.87%	$18,244,596.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	4,250,826	0	0.00%	$18,108,519.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	3,872,202	-40,879	-1.04%	$16,495,581.00
Financial Engines Advisors L.L.C.	31 Dec, 2025	3,828,717	2,447,360	177.17%	$16,310,334.00
BlackRock, Inc.	31 Dec, 2025	3,669,393	1,287,481	54.05%	$15,631,615.00
ORBIMED ADVISORS LLC	31 Dec, 2025	3,525,650	-4,935,850	-58.33%	$15,019,269.00
Vivo Capital, LLC	31 Dec, 2025	2,884,615	0	0.00%	$12,288,460.00
Eversept Partners, LP	31 Dec, 2025	2,507,090	2,507,090	0.00%	$10,680,203.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	2,460,944	2,013,191	449.62%	$10,483,622.00
Woodline Partners LP	31 Dec, 2025	2,337,005	0	0.00%	$9,955,641.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	1,560,755	831,057	113.89%	$6,648,816.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,525,666	-43,632	-2.78%	$6,502,652.00

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