Cogent Biosciences, Inc. (COGT) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

152,285,648Shares Outstanding

9,277,524Shares held by institutions

$349,020,453Value of institutional holdings

111.66%Institutional ownership %

10.80%Shares Changed QoQ

255No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Cogent Biosciences, Inc. (NASDAQ:COGT) includes 255 filers as of the latest reporting cycle ending December 2025.

These investors collectively held 111.7% of the company's total shares outstanding in December 2025, up from 98.9% in September 2025.
Quarterly data indicates a 10.80% shift in institutional share volume, and the annual owner count reflects an increase of 44.07%.
Of these 255 institutional investors, 175 increased their holdings in Cogent Biosciences, while 66 of them reduced positions, and 14 investors maintained their exposure.
The aggregate institutional position in Cogent Biosciences now stands at 170.05Mn shares as of December 2025, after investors increased their holdings (up by 16.58Mn shares quarter on quarter which is up 47.95Mn shares year over year).
As of December 31, 2025, FMR LLC held Cogent Biosciences's largest shareholding position with over 23.09Mn shares, representing 15.16% of total outstanding shares.
Among the most significant buyers of Cogent Biosciences during December 2025 were RTW INVESTMENTS, LP (4.12Mn), VANGUARD GROUP INC (3.76Mn), BlackRock, Inc. (2.61Mn), WELLINGTON MANAGEMENT GROUP LLP (2.31Mn), LORD, ABBETT & CO. LLC (1.87Mn).
Leading sellers of Cogent Biosciences stock in December 2025 included Commodore Capital LP (5.05Mn), VR Adviser, LLC (2.00Mn), Kynam Capital Management, LP (1.72Mn), UBS Group AG (1.59Mn), Nantahala Capital Management, LLC (1.26Mn).
The top 10 institutional holders of Cogent Biosciences for the quarter ending December 2025 included FMR LLC (23.09Mn), BlackRock, Inc. (12.97Mn), VANGUARD GROUP INC (11.51Mn), DEERFIELD MANAGEMENT COMPANY, L.P. (9.04Mn), Fairmount Funds Management LLC (9.00Mn), RTW INVESTMENTS, LP (7.59Mn), Kynam Capital Management, LP (6.17Mn), TCG Crossover Management, LLC (5.87Mn), STATE STREET CORP (4.94Mn), JANUS HENDERSON GROUP PLC (4.54Mn).

255 Institutional Holders

9,277,524 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	23,086,967	678,704	3.03%	$820,049,063.00
BlackRock, Inc.	31 Dec, 2025	12,974,591	2,605,056	25.12%	$460,857,474.00
VANGUARD GROUP INC	31 Dec, 2025	11,514,326	3,756,664	48.43%	$408,988,860.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	9,043,903	-9,215	-0.10%	$321,239,435.00
Fairmount Funds Management LLC	31 Dec, 2025	9,003,418	0	0.00%	$319,801,407.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,592,241	4,124,755	118.96%	$269,676,400.00
Kynam Capital Management, LP	31 Dec, 2025	6,165,223	-1,720,949	-21.82%	$218,988,721.00
TCG Crossover Management, LLC	31 Dec, 2025	5,868,162	-930,000	-13.68%	$208,437,114.00
STATE STREET CORP	31 Dec, 2025	4,940,300	164,881	3.45%	$175,479,456.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	4,537,408	1,359,365	42.77%	$161,114,684.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,514,562	240,407	7.34%	$124,861,950.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	2,712,336	2,305,437	566.59%	$96,342,176.00
Vivo Capital, LLC	31 Dec, 2025	2,398,993	-390,144	-13.99%	$85,212,231.00
Octagon Capital Advisors LP	31 Dec, 2025	2,350,000	-524,111	-18.24%	$83,472,000.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,247,804	716,879	46.83%	$79,841,998.00
Duquesne Family Office LLC	31 Dec, 2025	2,214,470	1,154,890	109.00%	$78,658.00
Commodore Capital LP	31 Dec, 2025	2,196,845	-5,053,155	-69.70%	$78,031,934.00
VR Adviser, LLC	31 Dec, 2025	2,000,000	-2,000,000	-50.00%	$71,040,000.00
Sofinnova Investments, Inc.	31 Dec, 2025	1,973,625	-154,316	-7.25%	$70,103,160.00
LORD, ABBETT & CO. LLC	31 Dec, 2025	1,870,537	1,870,537	0.00%	$66,441.00

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