Biocryst Pharmaceuticals Inc (BCRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

219,885,000Shares Outstanding

214,647,623Shares held by institutions

$1,841,676,605Value of institutional holdings

97.62%Institutional ownership %

19.65%Shares Changed QoQ

267No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Biocryst Pharmaceuticals Inc (NASDAQ:BCRX) is held by 266 institutional investors per 13F filings through December 2025.

Collectively, these holders controlled 94.4% of Biocryst Pharmaceuticals's outstanding shares in December 2025, up from 89.9% in September 2025.
Their total shares held in BCRX increased 16.5% from the prior quarter, while the number of investors in Biocryst Pharmaceuticals increased 4.31% year over year.
During the quarter, 137 of these 266 funds increased positions in BCRX, 98 reduced exposure, and 31 held steady.
Institutional investors collectively held 207.54Mn shares in Biocryst Pharmaceuticals as of December 2025, up by 29.39Mn shares quarter on quarter, and up 36.36Mn shares year over year.
As of December 31, 2025, the biggest holder of Biocryst Pharmaceuticals is VANGUARD GROUP INC at 22.27Mn shares, representing 10.13% of shares outstanding.
Leading buyers of Biocryst Pharmaceuticals shares for the quarter ending December 2025 were RA CAPITAL MANAGEMENT, L.P. (15.83Mn), Janus Henderson Group Plc (7.31Mn), Royalty Pharma Sub-Manager, LLC (3.85Mn), Goldman Sachs Group Inc (3.71Mn), PERCEPTIVE ADVISORS LLC (3.16Mn).
Top sellers of BCRX stock for the quarter ending December 2025 included ARROWSTREET CAPITAL, LIMITED PARTNERSHIP (5.16Mn), Morgan Stanley (3.46Mn), Assenagon Asset Management S.A. (2.73Mn), Bank Of America Corp /De/ (2.27Mn), Jpmorgan Chase & Co (1.42Mn).
According to Business Quant data, leading holders of BCRX for December 2025 are VANGUARD GROUP INC (22.27Mn), BlackRock, Inc. (21.14Mn), RA CAPITAL MANAGEMENT, L.P. (15.83Mn), DEERFIELD MANAGEMENT COMPANY, L.P. (14.34Mn), State Street Corp (11.07Mn), Kynam Capital Management, LP (9.37Mn), Janus Henderson Group Plc (7.4Mn), Goldman Sachs Group Inc (6.43Mn), UBS Group AG (5.26Mn), GEODE CAPITAL MANAGEMENT, LLC (5.05Mn).

267 Institutional Holders

214,647,623 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	22,273,375	482,494	2.21%	$173,732,325.00
BlackRock, Inc.	31 Dec, 2025	21,137,791	-108,085	-0.51%	$164,874,767.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	15,827,186	15,827,186	0.00%	$123,452,051.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	14,341,000	2,172,000	17.85%	$111,859,800.00
State Street Corp	31 Dec, 2025	11,073,211	1,265,773	12.91%	$86,371,046.00
Kynam Capital Management, LP	31 Dec, 2025	9,366,526	-23,744	-0.25%	$73,058,903.00
Janus Henderson Group Plc	31 Dec, 2025	7,404,386	7,310,745	7,807.21%	$57,791,233.00
Goldman Sachs Group Inc	31 Dec, 2025	6,425,570	3,713,764	136.95%	$50,119,446.00
UBS Group AG	31 Dec, 2025	5,263,914	-703,823	-11.79%	$41,058,529.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	5,053,786	1,479	0.03%	$39,426,800.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	4,515,317	95,688	2.17%	$35,219,473.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	4,089,112	-151,600	-3.57%	$31,895,074.00
Royalty Pharma Sub-Manager, LLC	31 Dec, 2025	3,846,154	3,846,154	0.00%	$30,000,001.00
Nuveen, LLC	31 Dec, 2025	3,612,366	-5,516	-0.15%	$28,176,454.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	3,162,529	3,162,529	0.00%	$24,667,726.00
GW&K Investment Management, LLC	31 Dec, 2025	3,160,924	963,159	43.82%	$24,655.00
Eversept Partners, LP	31 Dec, 2025	2,992,895	1,619,270	117.88%	$23,344,581.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	2,822,727	2,822,727	0.00%	$22,017,271.00
BNP PARIBAS FINANCIAL MARKETS	31 Dec, 2025	2,542,714	448,436	21.41%	$19,833,169.00
Fisher Asset Management, LLC	31 Dec, 2025	2,467,567	-165,129	-6.27%	$19,247,022.00

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