Biocryst Pharmaceuticals Inc (BCRX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

219,885,000Shares Outstanding

214,786,830Shares held by institutions

$2,053,362,095Value of institutional holdings

97.68%Institutional ownership %

19.72%Shares Changed QoQ

268No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Biocryst Pharmaceuticals Inc (NASDAQ:BCRX) has 266 institutional investors that have filed 13F reports for the period ending December 2025.

They owned 94.4% of outstanding stock in December 2025, up from 89.9% the prior quarter.
Their total shares held in BCRX increased 16.5% from the prior quarter, while the number of investors in Biocryst Pharmaceuticals increased 4.31% year over year.
Among the 266 funds, 137 bought more Biocryst Pharmaceuticals shares, 98 sold down, and 31 held their ground.
In total, institutional investors held 207.54Mn shares in Biocryst Pharmaceuticals as of December 2025, up by 29.39Mn shares quarter on quarter, and up 36.36Mn shares year over year.
As of December 31, 2025, the biggest holder of Biocryst Pharmaceuticals is RFG Advisory, LLC at 2.87Mn shares, representing 1.31% of shares outstanding.
Top purchasers of BCRX stock for the quarter ending December 2025 included RFG Advisory, LLC (2.87Mn), OP Asset Management Ltd (2.37Mn), Capricorn Fund Managers Ltd (202.9K), Janney Montgomery Scott LLC (137.13K), DOLIVER ADVISORS, LP (100.0K).
Leading sellers of Biocryst Pharmaceuticals shares for the quarter ending December 2025 were Pictet Asset Management Holding SA (268.94K), Assenagon Asset Management S.A. (126.63K), SG Americas Securities, LLC (106.04K), Bayforest Capital Ltd (8.48K), Inspire Investing, LLC (6.17K).
Business Quant data shows the 10 biggest positions in Biocryst Pharmaceuticals as of December 2025 are held by RFG Advisory, LLC (2.87Mn), OP Asset Management Ltd (2.51Mn), Pictet Asset Management Holding SA (471.57K), DOLIVER ADVISORS, LP (374.33K), Assenagon Asset Management S.A. (232.95K), Capricorn Fund Managers Ltd (202.9K), Janney Montgomery Scott LLC (163.27K), QTR Family Wealth, LLC (157.06K), Inspire Investing, LLC (53.88K), E Fund Management Co., Ltd. (44.53K).

272 Institutional Holders

214,786,830 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	22,273,375	482,494	2.21%	$173,732,325.00
BlackRock, Inc.	31 Dec, 2025	21,137,791	-108,085	-0.51%	$164,874,767.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	15,827,186	15,827,186	0.00%	$123,452,051.00
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	14,341,000	2,172,000	17.85%	$111,859,800.00
State Street Corp	31 Dec, 2025	11,073,211	1,265,773	12.91%	$86,371,046.00
Kynam Capital Management, LP	31 Dec, 2025	9,366,526	-23,744	-0.25%	$73,058,903.00
Janus Henderson Group Plc	31 Dec, 2025	7,404,386	7,310,745	7,807.21%	$57,791,233.00
Goldman Sachs Group Inc	31 Dec, 2025	6,425,570	3,713,764	136.95%	$50,119,446.00
UBS Group AG	31 Dec, 2025	5,263,914	-703,823	-11.79%	$41,058,529.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	5,053,786	1,479	0.03%	$39,426,800.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	4,515,317	95,688	2.17%	$35,219,473.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	4,089,112	-151,600	-3.57%	$31,895,074.00
Royalty Pharma Sub-Manager, LLC	31 Dec, 2025	3,846,154	3,846,154	0.00%	$30,000,001.00
Nuveen, LLC	31 Dec, 2025	3,612,366	-5,516	-0.15%	$28,176,454.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	3,162,529	3,162,529	0.00%	$24,667,726.00
GW&K Investment Management, LLC	31 Dec, 2025	3,160,924	963,159	43.82%	$24,655.00
Eversept Partners, LP	31 Dec, 2025	2,992,895	1,619,270	117.88%	$23,344,581.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	2,822,727	2,822,727	0.00%	$22,017,271.00
BNP PARIBAS FINANCIAL MARKETS	31 Dec, 2025	2,542,714	448,436	21.41%	$19,833,169.00
Fisher Asset Management, LLC	31 Dec, 2025	2,467,567	-165,129	-6.27%	$19,247,022.00

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