Assembly Biosciences, Inc. (ASMB) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

12,772,222Shares Outstanding

7,955,118Shares held by institutions

$221,311,383Value of institutional holdings

104.82%Institutional ownership %

11.58%Shares Changed QoQ

66No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Assembly Biosciences, Inc. (NASDAQ:ASMB) currently has 66 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

The collective stake of institutional investors in Assembly Biosciences moved to 104.8% in December 2025, a shift up from the 100.4% reported for September 2025.
Quarterly data indicates a 11.58% shift in institutional share volume, and the annual owner count reflects an increase of 88.57%.
The latest 13F cycle for Assembly Biosciences reveals that of 66 total investors, 42 funds grew their exposure, whereas 13 reduced theirs and 11 made no changes.
Collectively, institutional investors increased their stake in Assembly Biosciences to 13.39Mn shares as of December 2025, a change that is up by 1.39Mn shares quarter on quarter and up 10.20Mn shares year over year.
GILEAD SCIENCES, INC.'s holding of 4.51Mn shares as of December 31, 2025 makes it the primary institutional investor in Assembly Biosciences, owning 35.27% of the stock.
Among the most significant buyers of Assembly Biosciences during December 2025 were Paradigm Biocapital Advisors LP (665.25K), Point72 Asset Management, L.P. (304.59K), ADAGE CAPITAL PARTNERS GP, L.L.C. (161.00K), Eversept Partners, LP (159.68K), STEMPOINT CAPITAL LP (90.60K).
Leading sellers of Assembly Biosciences stock in December 2025 included Caption Management, LLC (243.21K), RENAISSANCE TECHNOLOGIES LLC (144.37K), Blackstone Inc. (129.03K), Schonfeld Strategic Advisors LLC (67.65K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (50.63K).
The top 10 institutional holders of Assembly Biosciences for the quarter ending December 2025 included GILEAD SCIENCES, INC. (4.51Mn), FARALLON CAPITAL MANAGEMENT LLC (1.23Mn), RA CAPITAL MANAGEMENT, L.P. (1.02Mn), Commodore Capital LP (1.00Mn), JANUS HENDERSON GROUP PLC (837.92K), Paradigm Biocapital Advisors LP (665.25K), Point72 Asset Management, L.P. (600.61K), VANGUARD GROUP INC (572.90K), Blackstone Inc. (318.75K), FRANKLIN RESOURCES INC (210.53K).

66 Institutional Holders

7,955,118 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
GILEAD SCIENCES, INC.	31 Dec, 2025	4,505,391	0	0.00%	$153,228,348.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,227,590	0	0.00%	$41,750,336.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	1,020,410	0	0.00%	$34,704,144.00
Commodore Capital LP	31 Dec, 2025	1,000,000	0	0.00%	$34,010,000.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	837,925	85,299	11.33%	$28,539,726.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	665,251	665,251	0.00%	$22,625,187.00
Point72 Asset Management, L.P.	31 Dec, 2025	600,609	304,592	102.90%	$20,426,712.00
VANGUARD GROUP INC	31 Dec, 2025	572,898	70,786	14.10%	$19,484,260.00
Blackstone Inc.	31 Dec, 2025	318,754	-129,035	-28.82%	$10,840,824.00
FRANKLIN RESOURCES INC	31 Dec, 2025	210,528	-27,641	-11.61%	$7,160,057.00
BlackRock, Inc.	31 Dec, 2025	192,296	22,097	12.98%	$6,539,986.00
B Group, Inc.	31 Dec, 2025	175,706	0	0.00%	$5,975,761.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	161,000	161,000	0.00%	$5,475,610.00
Eversept Partners, LP	31 Dec, 2025	159,676	159,676	0.00%	$5,430,581.00
STEMPOINT CAPITAL LP	31 Dec, 2025	156,728	90,598	137.00%	$5,330,319.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	131,307	1,212	0.93%	$4,467,714.00
MARSHALL WACE, LLP	31 Dec, 2025	129,075	43,860	51.47%	$4,389,840.00
Patient Square Capital LP	31 Dec, 2025	127,000	-8,182	-6.05%	$4,319,270.00
Caption Management, LLC	31 Dec, 2025	106,591	-243,209	-69.53%	$3,625,160.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	98,221	76,613	354.56%	$3,340,496.00

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