Anaptysbio, Inc (ANAB) Institutional Ownership

Ownership Summary

A total of 164 institutions have reported a stake in Anaptysbio, Inc (NASDAQ:ANAB) as of September 2025, according to recent 13F filings with the SEC.

• Anaptysbio saw its institutional ownership percentage fell to 113.3% in September 2025 from 124.8% in June 2025.
• On a quarter-over-quarter basis, institutional holdings shifted by -15.25%, with a year-over-year an increase of 1.86% in the count of filers.
• Of these 164 institutional investors, 62 increased their holdings in Anaptysbio, while 72 of them reduced positions, and 30 investors maintained their exposure.
• The aggregate institutional position in Anaptysbio now stands at 31.71Mn shares as of September 2025, after investors decreased their holdings (down by 5.71Mn shares quarter on quarter which is down 2.14Mn shares year over year).
• EcoR1 Capital, LLC continues to be the largest institutional holder of Anaptysbio as of September 30, 2025, with a position of 7.88Mn shares, representing 28.15% of the company's outstanding stock.
• Among the most significant buyers of Anaptysbio during September 2025 were MILLENNIUM MANAGEMENT LLC (1.33Mn), Assenagon Asset Management S.A. (822.98K), Soleus Capital Management, L.P. (305.00K), D. E. Shaw & Co., Inc. (237.01K), ARROWSTREET CAPITAL, LIMITED PARTNERSHIP (219.65K).
• Leading sellers of Anaptysbio stock in September 2025 included First Light Asset Management, LLC (2.55Mn), UBS Group AG (1.20Mn), CITIGROUP INC (975.95K), BANK OF AMERICA CORP /DE/ (949.56K), Sofinnova Investments, Inc. (778.09K).
• The top 10 institutional holders of Anaptysbio for the quarter ending September 2025 included EcoR1 Capital, LLC (7.88Mn), Point72 Asset Management, L.P. (2.27Mn), BlackRock, Inc. (1.72Mn), MORGAN STANLEY (1.56Mn), MILLENNIUM MANAGEMENT LLC (1.53Mn), VANGUARD GROUP INC (1.48Mn), TANG CAPITAL MANAGEMENT LLC (1.33Mn), First Light Asset Management, LLC (990.16K), STATE STREET CORP (873.43K), Assenagon Asset Management S.A. (839.93K).