Acadia Pharmaceuticals Inc (ACAD) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

170,902,381Shares Outstanding

51,023,553Shares held by institutions

$1,170,990,541Value of institutional holdings

96.42%Institutional ownership %

0.62%Shares Changed QoQ

318No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Acadia Pharmaceuticals Inc (NASDAQ:ACAD) includes 318 filers as of the latest reporting cycle ending December 2025.

The collective stake of institutional investors in Acadia Pharmaceuticals moved to 96.4% in December 2025, a shift down from the 98.8% reported for September 2025.
Institutional share ownership changed by 0.62% QoQ, while the number of institutional owners saw an increase of 8.53% YoY.
Of these 318 institutional investors, 166 increased their holdings in Acadia Pharmaceuticals, while 111 of them reduced positions, and 41 investors maintained their exposure.
The total number of shares held by institutions in Acadia Pharmaceuticals increased to 164.79Mn as of December 2025, a net change of up by 1.01Mn shares quarter on quarter, and up 1.70Mn shares year over year.
With 42.90Mn shares, BAKER BROS. ADVISORS LP commands the largest institutional position in Acadia Pharmaceuticals as of December 31, 2025, equating to 25.10% of the company.
Among the most significant buyers of Acadia Pharmaceuticals during December 2025 were Point72 Asset Management, L.P. (1.89Mn), NORGES BANK (1.51Mn), Trails Edge Capital Partners, LP (1.42Mn), CITADEL ADVISORS LLC (1.04Mn), Logos Global Management LP (850.00K).
Leading sellers of Acadia Pharmaceuticals stock in December 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (2.48Mn), MARSHALL WACE, LLP (1.87Mn), CITIGROUP INC (1.49Mn), TANG CAPITAL MANAGEMENT LLC (1.20Mn), MILLENNIUM MANAGEMENT LLC (929.56K).
The top 10 institutional holders of Acadia Pharmaceuticals for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (42.90Mn), BlackRock, Inc. (20.76Mn), VANGUARD GROUP INC (15.15Mn), STATE STREET CORP (7.91Mn), RTW INVESTMENTS, LP (7.14Mn), Point72 Asset Management, L.P. (3.38Mn), GEODE CAPITAL MANAGEMENT, LLC (3.24Mn), DIMENSIONAL FUND ADVISORS LP (2.92Mn), Palo Alto Investors LP (2.48Mn), FIRST TRUST ADVISORS LP (2.27Mn).

318 Institutional Holders

51,023,553 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	42,896,690	0	0.00%	$1,145,770,590.00
BlackRock, Inc.	31 Dec, 2025	20,755,452	486,808	2.40%	$554,378,124.00
VANGUARD GROUP INC	31 Dec, 2025	15,153,957	-25,414	-0.17%	$404,762,192.00
STATE STREET CORP	31 Dec, 2025	7,910,733	655,257	9.03%	$211,295,678.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,144,524	0	0.00%	$190,830,236.00
Point72 Asset Management, L.P.	31 Dec, 2025	3,377,311	1,890,954	127.22%	$90,207,977.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,239,451	106,807	3.41%	$86,539,034.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	2,920,974	122,840	4.39%	$78,018,583.00
Palo Alto Investors LP	31 Dec, 2025	2,484,031	17,347	0.70%	$66,348,468.00
FIRST TRUST ADVISORS LP	31 Dec, 2025	2,270,034	326,882	16.82%	$60,632,608.00
BRAIDWELL LP	31 Dec, 2025	2,032,021	-346,634	-14.57%	$54,275,281.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,570,051	-622,199	-28.38%	$41,936,063.00
FRED ALGER MANAGEMENT, LLC	31 Dec, 2025	1,559,962	-7,073	-0.45%	$41,666,585.00
Pictet Asset Management Holding SA	31 Dec, 2025	1,547,103	84,055	5.75%	$41,493,266.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,532,596	83,063	5.73%	$40,935,639.00
NORGES BANK	31 Dec, 2025	1,507,527	1,507,527	0.00%	$40,266,046.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	1,502,617	-146,247	-8.87%	$40,134,900.00
Trails Edge Capital Partners, LP	31 Dec, 2025	1,419,406	1,419,406	0.00%	$37,912,334.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,367,459	1,043,939	322.68%	$36,524,830.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	1,297,198	683,361	111.33%	$34,648,159.00

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