Zymeworks (ZYME) Return on Equity [ROE] (2022 - 2026)
Zymeworks (ZYME) posted Return on Equity [ROE] of -122.97% for Q2 2026, down 100.62 percentage points from -22.34% a year earlier and down 75.45 percentage points from the prior quarter.
Zymeworks (ZYME) Return on Equity [ROE] (2022 - 2026) Analysis & Trends
For FY2025, Zymeworks' Return on Equity [ROE] came in at -26.72%, up 3.82 percentage points from FY2024.
- Annual Return on Equity [ROE] shows a four-year change of +37.57 percentage points (FY2021 to FY2025).
- In prior years, Zymeworks' Return on Equity [ROE] was -30.54% in FY2024 (-5.76 pp), -24.78% in FY2023 (-58.29 pp), 33.51% in FY2022 (+97.80 pp) and -64.29% in FY2021.
- The Q2 2026 figure stands as the lowest quarterly Return on Equity [ROE] in data going back to Q2 2022.
- On a year-over-year basis, Return on Equity [ROE] increased in three of the last eight quarters, with an average year-over-year change of -22.90 percentage points.
- The strongest year-over-year quarter for Return on Equity [ROE] in the past five years was Q3 2023, with a gain of 158.56 percentage points; the weakest was Q2 2026, with a drop of 100.62 percentage points.
- According to Business Quant data, Return on Equity [ROE] for the three prior quarters was -47.52% (Q1 2026), -27.57% (Q4 2025) and -19.38% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Zymeworks | 2.24 Bn | 1.27 Bn | - | 25.20% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 25.20% |
| Jun 30, 2026 | -123.26% |
| Mar 31, 2026 | -47.59% |
| Dec 31, 2025 | -27.27% |
| Sep 30, 2025 | -19.40% |
| Jun 30, 2025 | -21.87% |
| Mar 31, 2025 | -33.86% |
| Dec 31, 2024 | -34.87% |
| Sep 30, 2024 | -28.81% |
| Jun 30, 2024 | -26.68% |
| Mar 31, 2024 | -28.30% |
| Dec 31, 2023 | -26.68% |
| Sep 30, 2023 | 46.63% |
| Jun 30, 2023 | 40.09% |
| Mar 31, 2023 | 35.87% |
| Dec 31, 2022 | 36.97% |
| Sep 30, 2022 | -111.55% |
| Jun 30, 2022 | -93.90% |
Zymeworks Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ZYME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();