Zymeworks (ZYME) Return on Equity [ROE] (2022 - 2026)
Zymeworks (ZYME) posted Return on Equity [ROE] of -122.97% for Q2 2026, down 100.62 percentage points from -22.34% a year earlier and down 75.45 percentage points from the prior quarter.
Zymeworks (ZYME) Return on Equity [ROE] (2022 - 2026) Analysis & Trends
For FY2025, Zymeworks' Return on Equity [ROE] came in at -26.72%, up 3.82 percentage points from FY2024.
- Annual Return on Equity [ROE] shows a four-year change of +37.57 percentage points (FY2021 to FY2025).
- In prior years, Zymeworks' Return on Equity [ROE] was -30.54% in FY2024 (-5.76 pp), -24.78% in FY2023 (-58.29 pp), 33.51% in FY2022 (+97.80 pp) and -64.29% in FY2021.
- The Q2 2026 figure stands as the lowest quarterly Return on Equity [ROE] in data going back to Q2 2022.
- On a year-over-year basis, Return on Equity [ROE] increased in three of the last eight quarters, with an average year-over-year change of -22.90 percentage points.
- The strongest year-over-year quarter for Return on Equity [ROE] in the past five years was Q3 2023, with a gain of 158.56 percentage points; the weakest was Q2 2026, with a drop of 100.62 percentage points.
- According to Business Quant data, Return on Equity [ROE] for the three prior quarters was -47.52% (Q1 2026), -27.57% (Q4 2025) and -19.38% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Zymeworks | 1.89 Bn | 775.55 Mn | - | -122.97% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -122.97% |
| Mar 31, 2026 | -47.52% |
| Dec 31, 2025 | -27.57% |
| Sep 30, 2025 | -19.38% |
| Jun 30, 2025 | -22.34% |
| Mar 31, 2025 | -34.25% |
| Dec 31, 2024 | -34.77% |
| Sep 30, 2024 | -29.41% |
| Jun 30, 2024 | -26.66% |
| Mar 31, 2024 | -27.91% |
| Dec 31, 2023 | -26.69% |
| Sep 30, 2023 | 47.01% |
| Jun 30, 2023 | 40.34% |
| Mar 31, 2023 | 35.72% |
| Dec 31, 2022 | 36.97% |
| Sep 30, 2022 | -111.55% |
| Jun 30, 2022 | -93.90% |
Zymeworks Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ZYME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();