Zymeworks (ZYME) Return on Assets [ROA] (2022 - 2026)
Zymeworks' Return on Assets [ROA] came in at -34.28% for Q2 2026, down 16.61 percentage points from -17.67% a year earlier and down 9.38 percentage points from the prior quarter.
Zymeworks (ZYME) Return on Assets [ROA] (2022 - 2026) Analysis & Trends
For FY2025, Zymeworks' Return on Assets [ROA] was -20.04%, up 3.46 percentage points from FY2024.
- Return on Assets [ROA] carries a three-year change of -44.00 percentage points (FY2022 to FY2025).
- Going back by year, Return on Assets [ROA] was -23.51% in FY2024 (-4.20 pp), -19.30% in FY2023 (-43.26 pp) and 23.96% in FY2022.
- The Q2 2026 figure represents the lowest quarterly Return on Assets [ROA] in data going back to Q4 2022.
- Year-over-year, Return on Assets [ROA] increased in four of the last eight quarters, with an average year-over-year change of -8.51 percentage points.
- The fastest year-over-year change in Return on Assets [ROA] over five years came in Q3 2025 (a gain of 6.93 percentage points), and the weakest in Q3 2024 (a drop of 58.11 percentage points).
- Business Quant data shows ZYME's Return on Assets [ROA] at -24.89% (Q1 2026), -21.82% (Q4 2025) and -15.75% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 10.47% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 4.65% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 2.45% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 28.37% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 9.10% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 9.29% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -6.13% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 2.14% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 16.34% |
| 10 | Zymeworks | 1.89 Bn | 775.55 Mn | - | -34.28% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -34.28% |
| Mar 31, 2026 | -24.89% |
| Dec 31, 2025 | -21.82% |
| Sep 30, 2025 | -15.75% |
| Jun 30, 2025 | -17.67% |
| Mar 31, 2025 | -25.59% |
| Dec 31, 2024 | -25.82% |
| Sep 30, 2024 | -22.67% |
| Jun 30, 2024 | -21.04% |
| Mar 31, 2024 | -22.21% |
| Dec 31, 2023 | -20.87% |
| Sep 30, 2023 | 35.43% |
| Jun 30, 2023 | 30.94% |
| Mar 31, 2023 | 27.63% |
| Dec 31, 2022 | 26.20% |
Zymeworks Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "ZYME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=ZYME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();