Zymeworks ZYME
NASDAQ ZYME
$29.28 -0.62 (-2.07%)
As of: Sep 4, 2026 · 12:45 PM EDT

Zymeworks (ZYME) Operating Income (2021 - 2026)

Zymeworks (ZYME) posted Operating Income of -$47.1 million for Q1 2026, down 6.72% sequentially from -$44.2 million in Q4 2025, and down 83.96% YoY from -$293.8 million in Q1 2025.

Analysis

Zymeworks (ZYME) Operating Income (2021 - 2026) Analysis & Trends

Zymeworks has reported Operating Income for 6 years, with the latest figure at -$47.1 million in Q1 2026.

  • Quarterly Operating Income fell 83.96% year-over-year to -$47.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$114.1 million (up 8.7% YoY) and the FY2025 annual result came in at -$92.5 million, up 32.5% from the prior year.
  • Operating Income fell to -$47.1 million in Q1 2026 per ZYME's latest filing, from -$44.2 million in the prior quarter.
  • Over five years, Operating Income peaked at $319.4 million in Q4 2022 and troughed at -$72.7 million in Q1 2022.
  • A 5-year average of -$16.7 million and a median of -$34.2 million in 2024 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2022 and 2023: Operating Income soared 881.89% in 2022, then tumbled 107.33% in 2023.
  • Over 5 years, Operating Income stood at $319.4 million in 2022, then plunged by 107.33% to -$23.4 million in 2023, then advanced by 5.14% to -$22.2 million in 2024, then slumped by 98.73% to -$44.2 million in 2025, then slipped by 6.72% to -$47.1 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$47.1 million, -$44.2 million, and -$22.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 139.62 Bn 131.77 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.73 Bn 77.73 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.53 Bn 58.35 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.23 Bn 53.09 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.05 Bn 44.05 Bn - -505.13 Mn
6 BeOne Medicines 40.03 Bn 34.93 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.19 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.52 Bn 27.68 Bn - 133.12 Mn
9 Insmed 27.46 Bn 26.30 Bn 358.27 Mn -1.55 Mn
10 Zymeworks 2.14 Bn 1.87 Bn - -42.18 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -42.18 Mn
Mar 31, 2026 -47.12 Mn
Dec 31, 2025 -44.15 Mn
Sep 30, 2025 -22.11 Mn
Jun 30, 2025 -674,000.00
Mar 31, 2025 -25.61 Mn
Dec 31, 2024 -22.22 Mn
Sep 30, 2024 -34.21 Mn
Jun 30, 2024 -42.89 Mn
Mar 31, 2024 -37.80 Mn
Dec 31, 2023 -23.42 Mn
Sep 30, 2023 -33.24 Mn
Jun 30, 2023 -54.11 Mn
Mar 31, 2023 -27.28 Mn
Dec 31, 2022 319.40 Mn
Sep 30, 2022 -50.36 Mn
Jun 30, 2022 -65.82 Mn
Mar 31, 2022 -72.69 Mn
Dec 31, 2021 -40.85 Mn
Sep 30, 2021 -60.96 Mn