Zymeworks (ZYME) Operating Income (2021 - 2026)
Zymeworks (ZYME) reported Operating Income of -$47.1 million for Q1 2026, down 83.96% on a YoY basis from -$293.8 million in Q1 2025, and down 6.72% sequentially from -$44.2 million in Q4 2025.
Zymeworks (ZYME) Operating Income (2021 - 2026) Analysis & Trends
Zymeworks (ZYME) has 6 years of Operating Income data on file, last reported at -$47.1 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Income fell 83.96% year-over-year to -$47.1 million; the trailing twelve-month figure through Mar 2026 stood at -$114.1 million (up 8.7% YoY), and the FY2025 full-year result was -$92.5 million, up 32.5% from the prior year.
- Operating Income fell to -$47.1 million in Q1 2026, from -$44.2 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $319.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
- A 5-year average of -$16.7 million and a median of -$34.2 million in 2024 frame the typical range for Operating Income.
- Across the five-year window, Operating Income jumped 881.89% in 2022 and sank 107.33% in 2023, its largest moves.
- Tracing ZYME's Operating Income over 5 years: stood at $319.4 million in 2022, then sank by 107.33% to -$23.4 million in 2023, then increased by 5.14% to -$22.2 million in 2024, then tumbled by 98.73% to -$44.2 million in 2025, then fell by 6.72% to -$47.1 million in 2026.
- Business Quant data shows ZYME's Operating Income at -$47.1 million in Q1 2026, -$44.2 million in Q4 2025, and -$22.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -47.12 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -47.12 Mn |
| Dec 31, 2025 | -44.15 Mn |
| Sep 30, 2025 | -22.11 Mn |
| Jun 30, 2025 | -674,000.00 |
| Mar 31, 2025 | -25.61 Mn |
| Dec 31, 2024 | -22.22 Mn |
| Sep 30, 2024 | -34.21 Mn |
| Jun 30, 2024 | -42.89 Mn |
| Mar 31, 2024 | -37.80 Mn |
| Dec 31, 2023 | -23.42 Mn |
| Sep 30, 2023 | -33.24 Mn |
| Jun 30, 2023 | -54.11 Mn |
| Mar 31, 2023 | -27.28 Mn |
| Dec 31, 2022 | 319.40 Mn |
| Sep 30, 2022 | -50.36 Mn |
| Jun 30, 2022 | -65.82 Mn |
| Mar 31, 2022 | -72.69 Mn |
| Dec 31, 2021 | -40.85 Mn |
| Sep 30, 2021 | -60.96 Mn |