Zymeworks (ZYME) EBT (2021 - 2026)

Zymeworks' (ZYME) quarterly EBT came in at -$46.4 million in Q1 2026, down 109.36% year-on-year from $495.1 million in Q1 2025, and down 11.75% quarter-over-quarter from -$41.5 million in Q4 2025.

Zymeworks (ZYME) EBT (2021 - 2026) Analysis & Trends

Zymeworks has disclosed EBT across 6 years of filings, most recently posting -$46.4 million for Q1 2026.

  • EBT for Q1 2026 came in at -$46.4 million, down 109.36% year-over-year; the trailing twelve-month figure through Mar 2026 was -$104.0 million (up 2.99% YoY), and the FY2025 annual result was -$79.8 million, up 31.61% from the prior year.
  • EBT came in at -$46.4 million for Q1 2026 at Zymeworks, down from -$41.5 million in the prior quarter.
  • In the past five years, EBT ranged from a high of $320.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
  • The 5-year median for EBT is -$29.6 million (2024), against an average of -$13.3 million.
  • Across the five-year window, EBT jumped 890.75% in 2022 and tumbled 133.15% in 2025, its largest moves.
  • Zymeworks' EBT stood at $320.4 million in 2022, then plunged by 105.99% to -$19.2 million in 2023, then rose by 7.36% to -$17.8 million in 2024, then sank by 133.15% to -$41.5 million in 2025, then decreased by 11.75% to -$46.4 million in 2026.
  • The last three EBT figures came in at -$46.4 million (Q1 2026), -$41.5 million (Q4 2025), and -$18.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 19.60 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -15.31 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.18 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -1.50 Mn
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.25 Bn
9 Abivax 90.15 Bn 90.15 Bn - -56.48 Mn
10 Zymeworks 1.71 Bn 1.35 Bn - -46.35 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -46.35 Mn
Dec 31, 2025 -41.48 Mn
Sep 30, 2025 -18.27 Mn
Jun 30, 2025 2.13 Mn
Mar 31, 2025 -22.14 Mn
Dec 31, 2024 -17.79 Mn
Sep 30, 2024 -29.62 Mn
Jun 30, 2024 -37.62 Mn
Mar 31, 2024 -31.58 Mn
Dec 31, 2023 -19.20 Mn
Sep 30, 2023 -27.58 Mn
Jun 30, 2023 -49.50 Mn
Mar 31, 2023 -22.96 Mn
Dec 31, 2022 320.44 Mn
Sep 30, 2022 -47.88 Mn
Jun 30, 2022 -64.63 Mn
Mar 31, 2022 -72.70 Mn
Dec 31, 2021 -40.52 Mn
Sep 30, 2021 -59.82 Mn