Zymeworks (ZYME) EBT (2021 - 2026)

Zymeworks (ZYME) reported EBT of -$46.4 million for Q1 2026, down 109.36% on a YoY basis from $495.1 million in Q1 2025, and down 11.75% sequentially from -$41.5 million in Q4 2025.

Zymeworks (ZYME) EBT (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of EBT data on file, last reported at -$46.4 million in Q1 2026.

  • For the quarter ending Q1 2026, EBT fell 109.36% year-over-year to -$46.4 million; the trailing twelve-month figure through Mar 2026 stood at -$104.0 million (up 2.99% YoY), and the FY2025 full-year result was -$79.8 million, up 31.61% from the prior year.
  • EBT declined to -$46.4 million in Q1 2026, from -$41.5 million in the prior quarter.
  • In the past five years, EBT ranged from a high of $320.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
  • A 5-year average of -$13.3 million and a median of -$29.6 million in 2024 frame the typical range for EBT.
  • Across the five-year window, EBT jumped 890.75% in 2022 and sank 133.15% in 2025, its largest moves.
  • Tracing ZYME's EBT over 5 years: stood at $320.4 million in 2022, then sank by 105.99% to -$19.2 million in 2023, then increased by 7.36% to -$17.8 million in 2024, then slumped by 133.15% to -$41.5 million in 2025, then retreated by 11.75% to -$46.4 million in 2026.
  • Business Quant data shows ZYME's EBT at -$46.4 million in Q1 2026, -$41.5 million in Q4 2025, and -$18.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Zymeworks 1.70 Bn 1.34 Bn - -46.35 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -46.35 Mn
Dec 31, 2025 -41.48 Mn
Sep 30, 2025 -18.27 Mn
Jun 30, 2025 2.13 Mn
Mar 31, 2025 -22.14 Mn
Dec 31, 2024 -17.79 Mn
Sep 30, 2024 -29.62 Mn
Jun 30, 2024 -37.62 Mn
Mar 31, 2024 -31.58 Mn
Dec 31, 2023 -19.20 Mn
Sep 30, 2023 -27.58 Mn
Jun 30, 2023 -49.50 Mn
Mar 31, 2023 -22.96 Mn
Dec 31, 2022 320.44 Mn
Sep 30, 2022 -47.88 Mn
Jun 30, 2022 -64.63 Mn
Mar 31, 2022 -72.70 Mn
Dec 31, 2021 -40.52 Mn
Sep 30, 2021 -59.82 Mn