Zymeworks (ZYME) EBT (2021 - 2026)
Zymeworks' (ZYME) quarterly EBT came in at -$46.4 million in Q1 2026, down 109.36% year-on-year from $495.1 million in Q1 2025, and down 11.75% quarter-over-quarter from -$41.5 million in Q4 2025.
Zymeworks (ZYME) EBT (2021 - 2026) Analysis & Trends
Zymeworks has disclosed EBT across 6 years of filings, most recently posting -$46.4 million for Q1 2026.
- EBT for Q1 2026 came in at -$46.4 million, down 109.36% year-over-year; the trailing twelve-month figure through Mar 2026 was -$104.0 million (up 2.99% YoY), and the FY2025 annual result was -$79.8 million, up 31.61% from the prior year.
- EBT came in at -$46.4 million for Q1 2026 at Zymeworks, down from -$41.5 million in the prior quarter.
- In the past five years, EBT ranged from a high of $320.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
- The 5-year median for EBT is -$29.6 million (2024), against an average of -$13.3 million.
- Across the five-year window, EBT jumped 890.75% in 2022 and tumbled 133.15% in 2025, its largest moves.
- Zymeworks' EBT stood at $320.4 million in 2022, then plunged by 105.99% to -$19.2 million in 2023, then rose by 7.36% to -$17.8 million in 2024, then sank by 133.15% to -$41.5 million in 2025, then decreased by 11.75% to -$46.4 million in 2026.
- The last three EBT figures came in at -$46.4 million (Q1 2026), -$41.5 million (Q4 2025), and -$18.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.94 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | 19.60 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -15.31 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.18 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -1.50 Mn |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.25 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -56.48 Mn |
| 10 | Zymeworks | 1.71 Bn | 1.35 Bn | - | -46.35 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -46.35 Mn |
| Dec 31, 2025 | -41.48 Mn |
| Sep 30, 2025 | -18.27 Mn |
| Jun 30, 2025 | 2.13 Mn |
| Mar 31, 2025 | -22.14 Mn |
| Dec 31, 2024 | -17.79 Mn |
| Sep 30, 2024 | -29.62 Mn |
| Jun 30, 2024 | -37.62 Mn |
| Mar 31, 2024 | -31.58 Mn |
| Dec 31, 2023 | -19.20 Mn |
| Sep 30, 2023 | -27.58 Mn |
| Jun 30, 2023 | -49.50 Mn |
| Mar 31, 2023 | -22.96 Mn |
| Dec 31, 2022 | 320.44 Mn |
| Sep 30, 2022 | -47.88 Mn |
| Jun 30, 2022 | -64.63 Mn |
| Mar 31, 2022 | -72.70 Mn |
| Dec 31, 2021 | -40.52 Mn |
| Sep 30, 2021 | -59.82 Mn |