Zymeworks ZYME
NASDAQ ZYME
$29.48 -0.42 (-1.40%)
As of: Sep 4, 2026 · 2:19 PM EDT

Zymeworks (ZYME) EBITDA (2021 - 2026)

Zymeworks (ZYME) posted EBITDA of -$47.1 million for Q1 2026, down 6.72% sequentially from -$44.2 million in Q4 2025, and down 83.96% YoY from -$293.8 million in Q1 2025.

Analysis

Zymeworks (ZYME) EBITDA (2021 - 2026) Analysis & Trends

Zymeworks has reported EBITDA for 6 years, with the latest figure at -$47.1 million in Q1 2026.

  • Quarterly EBITDA fell 83.96% year-over-year to -$47.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$114.1 million (up 8.7% YoY) and the FY2025 annual result came in at -$92.5 million, up 32.5% from the prior year.
  • EBITDA fell to -$47.1 million in Q1 2026 per ZYME's latest filing, from -$44.2 million in the prior quarter.
  • Over five years, EBITDA peaked at $319.4 million in Q4 2022 and troughed at -$72.7 million in Q1 2022.
  • A 5-year average of -$16.7 million and a median of -$34.2 million in 2024 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2022 and 2023: EBITDA soared 881.89% in 2022, then tumbled 107.33% in 2023.
  • Over 5 years, EBITDA stood at $319.4 million in 2022, then plunged by 107.33% to -$23.4 million in 2023, then advanced by 5.14% to -$22.2 million in 2024, then slumped by 98.73% to -$44.2 million in 2025, then slipped by 6.72% to -$47.1 million in 2026.
  • According to Business Quant data, EBITDA over the past three periods registered -$47.1 million, -$44.2 million, and -$22.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 138.92 Bn 131.07 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.55 Bn 77.56 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.55 Bn 58.37 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.26 Bn 53.13 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.08 Bn 44.08 Bn - -505.13 Mn
6 BeOne Medicines 39.98 Bn 34.89 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.32 Bn 32.01 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.42 Bn 27.59 Bn - 133.12 Mn
9 Insmed 27.41 Bn 26.25 Bn 358.27 Mn -1.55 Mn
10 Zymeworks 2.15 Bn 1.88 Bn - -42.18 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -42.18 Mn
Mar 31, 2026 -47.12 Mn
Dec 31, 2025 -44.15 Mn
Sep 30, 2025 -22.11 Mn
Jun 30, 2025 -674,000.00
Mar 31, 2025 -25.61 Mn
Dec 31, 2024 -22.22 Mn
Sep 30, 2024 -34.21 Mn
Jun 30, 2024 -42.89 Mn
Mar 31, 2024 -37.80 Mn
Dec 31, 2023 -23.42 Mn
Sep 30, 2023 -33.24 Mn
Jun 30, 2023 -54.11 Mn
Mar 31, 2023 -27.28 Mn
Dec 31, 2022 319.40 Mn
Sep 30, 2022 -50.36 Mn
Jun 30, 2022 -65.82 Mn
Mar 31, 2022 -72.69 Mn
Dec 31, 2021 -40.85 Mn
Sep 30, 2021 -60.96 Mn