Zymeworks (ZYME) EBIT (2021 - 2026)
Zymeworks' (ZYME) quarterly EBIT came in at -$47.1 million in Q1 2026, down 83.96% year-on-year from -$293.8 million in Q1 2025, and down 6.72% quarter-over-quarter from -$44.2 million in Q4 2025.
Zymeworks (ZYME) EBIT (2021 - 2026) Analysis & Trends
Zymeworks has disclosed EBIT across 6 years of filings, most recently posting -$47.1 million for Q1 2026.
- EBIT for Q1 2026 came in at -$47.1 million, down 83.96% year-over-year; the trailing twelve-month figure through Mar 2026 was -$114.1 million (up 8.7% YoY), and the FY2025 annual result was -$92.5 million, up 32.5% from the prior year.
- EBIT came in at -$47.1 million for Q1 2026 at Zymeworks, down from -$44.2 million in the prior quarter.
- In the past five years, EBIT ranged from a high of $319.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
- The 5-year median for EBIT is -$34.2 million (2024), against an average of -$16.7 million.
- Across the five-year window, EBIT jumped 881.89% in 2022 and tumbled 107.33% in 2023, its largest moves.
- Zymeworks' EBIT stood at $319.4 million in 2022, then plunged by 107.33% to -$23.4 million in 2023, then rose by 5.14% to -$22.2 million in 2024, then slumped by 98.73% to -$44.2 million in 2025, then retreated by 6.72% to -$47.1 million in 2026.
- The last three EBIT figures came in at -$47.1 million (Q1 2026), -$44.2 million (Q4 2025), and -$22.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -1.51 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -47.12 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -47.12 Mn |
| Dec 31, 2025 | -44.15 Mn |
| Sep 30, 2025 | -22.11 Mn |
| Jun 30, 2025 | -674,000.00 |
| Mar 31, 2025 | -25.61 Mn |
| Dec 31, 2024 | -22.22 Mn |
| Sep 30, 2024 | -34.21 Mn |
| Jun 30, 2024 | -42.89 Mn |
| Mar 31, 2024 | -37.80 Mn |
| Dec 31, 2023 | -23.42 Mn |
| Sep 30, 2023 | -33.24 Mn |
| Jun 30, 2023 | -54.11 Mn |
| Mar 31, 2023 | -27.28 Mn |
| Dec 31, 2022 | 319.40 Mn |
| Sep 30, 2022 | -50.36 Mn |
| Jun 30, 2022 | -65.82 Mn |
| Mar 31, 2022 | -72.69 Mn |
| Dec 31, 2021 | -40.85 Mn |
| Sep 30, 2021 | -60.96 Mn |