Zymeworks (ZYME) EBIT (2021 - 2026)

Zymeworks (ZYME) reported EBIT of -$47.1 million for Q1 2026, down 83.96% on a YoY basis from -$293.8 million in Q1 2025, and down 6.72% sequentially from -$44.2 million in Q4 2025.

Zymeworks (ZYME) EBIT (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of EBIT data on file, last reported at -$47.1 million in Q1 2026.

  • For the quarter ending Q1 2026, EBIT fell 83.96% year-over-year to -$47.1 million; the trailing twelve-month figure through Mar 2026 stood at -$114.1 million (up 8.7% YoY), and the FY2025 full-year result was -$92.5 million, up 32.5% from the prior year.
  • EBIT fell to -$47.1 million in Q1 2026, from -$44.2 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of $319.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
  • A 5-year average of -$16.7 million and a median of -$34.2 million in 2024 frame the typical range for EBIT.
  • Across the five-year window, EBIT jumped 881.89% in 2022 and sank 107.33% in 2023, its largest moves.
  • Tracing ZYME's EBIT over 5 years: stood at $319.4 million in 2022, then sank by 107.33% to -$23.4 million in 2023, then increased by 5.14% to -$22.2 million in 2024, then tumbled by 98.73% to -$44.2 million in 2025, then fell by 6.72% to -$47.1 million in 2026.
  • Business Quant data shows ZYME's EBIT at -$47.1 million in Q1 2026, -$44.2 million in Q4 2025, and -$22.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Zymeworks 1.70 Bn 1.34 Bn - -47.12 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -47.12 Mn
Dec 31, 2025 -44.15 Mn
Sep 30, 2025 -22.11 Mn
Jun 30, 2025 -674,000.00
Mar 31, 2025 -25.61 Mn
Dec 31, 2024 -22.22 Mn
Sep 30, 2024 -34.21 Mn
Jun 30, 2024 -42.89 Mn
Mar 31, 2024 -37.80 Mn
Dec 31, 2023 -23.42 Mn
Sep 30, 2023 -33.24 Mn
Jun 30, 2023 -54.11 Mn
Mar 31, 2023 -27.28 Mn
Dec 31, 2022 319.40 Mn
Sep 30, 2022 -50.36 Mn
Jun 30, 2022 -65.82 Mn
Mar 31, 2022 -72.69 Mn
Dec 31, 2021 -40.85 Mn
Sep 30, 2021 -60.96 Mn