Zymeworks (ZYME) EBIT (2021 - 2026)

Zymeworks' (ZYME) quarterly EBIT came in at -$47.1 million in Q1 2026, down 83.96% year-on-year from -$293.8 million in Q1 2025, and down 6.72% quarter-over-quarter from -$44.2 million in Q4 2025.

Zymeworks (ZYME) EBIT (2021 - 2026) Analysis & Trends

Zymeworks has disclosed EBIT across 6 years of filings, most recently posting -$47.1 million for Q1 2026.

  • EBIT for Q1 2026 came in at -$47.1 million, down 83.96% year-over-year; the trailing twelve-month figure through Mar 2026 was -$114.1 million (up 8.7% YoY), and the FY2025 annual result was -$92.5 million, up 32.5% from the prior year.
  • EBIT came in at -$47.1 million for Q1 2026 at Zymeworks, down from -$44.2 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of $319.4 million in Q4 2022 to a low of -$72.7 million in Q1 2022.
  • The 5-year median for EBIT is -$34.2 million (2024), against an average of -$16.7 million.
  • Across the five-year window, EBIT jumped 881.89% in 2022 and tumbled 107.33% in 2023, its largest moves.
  • Zymeworks' EBIT stood at $319.4 million in 2022, then plunged by 107.33% to -$23.4 million in 2023, then rose by 5.14% to -$22.2 million in 2024, then slumped by 98.73% to -$44.2 million in 2025, then retreated by 6.72% to -$47.1 million in 2026.
  • The last three EBIT figures came in at -$47.1 million (Q1 2026), -$44.2 million (Q4 2025), and -$22.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.51 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - -47.12 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -47.12 Mn
Dec 31, 2025 -44.15 Mn
Sep 30, 2025 -22.11 Mn
Jun 30, 2025 -674,000.00
Mar 31, 2025 -25.61 Mn
Dec 31, 2024 -22.22 Mn
Sep 30, 2024 -34.21 Mn
Jun 30, 2024 -42.89 Mn
Mar 31, 2024 -37.80 Mn
Dec 31, 2023 -23.42 Mn
Sep 30, 2023 -33.24 Mn
Jun 30, 2023 -54.11 Mn
Mar 31, 2023 -27.28 Mn
Dec 31, 2022 319.40 Mn
Sep 30, 2022 -50.36 Mn
Jun 30, 2022 -65.82 Mn
Mar 31, 2022 -72.69 Mn
Dec 31, 2021 -40.85 Mn
Sep 30, 2021 -60.96 Mn