Zenas BioPharma (ZBIO) EBITDA (2023 - 2026)

Zenas BioPharma (ZBIO) recorded quarterly EBITDA of -$81.3 million in Q1 2026, up 66.19% quarter-over-quarter from -$240.4 million in Q4 2025, and down 141.78% on a YoY basis from $194.6 million in Q1 2025.

Zenas BioPharma (ZBIO) EBITDA (2023 - 2026) Analysis & Trends

Zenas BioPharma's EBITDA history runs 4 years deep, the most recent figure standing at -$81.3 million for Q1 2026.

  • In Q1 2026, EBITDA fell 141.78% year-over-year to -$81.3 million; the TTM figure through Mar 2026 stood at -$425.7 million (down 161.64% YoY), while the FY2025 annual figure was -$378.0 million, down 141.02% from the prior year.
  • EBITDA was -$81.3 million for Q1 2026 at Zenas BioPharma, up from -$240.4 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $35.6 million in Q3 2023 to a low of -$240.4 million in Q4 2025.
  • Historically, EBITDA has averaged -$55.0 million across 4 years, with a median of -$38.7 million in 2024.
  • Biggest YoY gain for EBITDA was 21.12% in 2025; the steepest drop was 358.3% in 2025.
  • A 4-year view of EBITDA shows it stood at -$24.7 million in 2023, then sank by 112.62% to -$52.5 million in 2024, then tumbled by 358.3% to -$240.4 million in 2025, then soared by 66.19% to -$81.3 million in 2026.
  • The last three EBITDA figures came in at -$81.3 million (Q1 2026), -$240.4 million (Q4 2025), and -$51.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Zenas BioPharma 1.10 Bn 379.43 Mn - -81.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -81.30 Mn
Dec 31, 2025 -240.44 Mn
Sep 30, 2025 -51.47 Mn
Jun 30, 2025 -52.46 Mn
Mar 31, 2025 -33.63 Mn
Dec 31, 2024 -52.46 Mn
Sep 30, 2024 -38.66 Mn
Jun 30, 2024 -37.95 Mn
Mar 31, 2024 -27.76 Mn
Dec 31, 2023 -24.67 Mn
Sep 30, 2023 35.62 Mn