Zenas BioPharma (ZBIO) EBITDA (2023 - 2026)
Zenas BioPharma (ZBIO) recorded quarterly EBITDA of -$81.3 million in Q1 2026, up 66.19% quarter-over-quarter from -$240.4 million in Q4 2025, and down 141.78% on a YoY basis from $194.6 million in Q1 2025.
Zenas BioPharma (ZBIO) EBITDA (2023 - 2026) Analysis & Trends
Zenas BioPharma's EBITDA history runs 4 years deep, the most recent figure standing at -$81.3 million for Q1 2026.
- In Q1 2026, EBITDA fell 141.78% year-over-year to -$81.3 million; the TTM figure through Mar 2026 stood at -$425.7 million (down 161.64% YoY), while the FY2025 annual figure was -$378.0 million, down 141.02% from the prior year.
- EBITDA was -$81.3 million for Q1 2026 at Zenas BioPharma, up from -$240.4 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of $35.6 million in Q3 2023 to a low of -$240.4 million in Q4 2025.
- Historically, EBITDA has averaged -$55.0 million across 4 years, with a median of -$38.7 million in 2024.
- Biggest YoY gain for EBITDA was 21.12% in 2025; the steepest drop was 358.3% in 2025.
- A 4-year view of EBITDA shows it stood at -$24.7 million in 2023, then sank by 112.62% to -$52.5 million in 2024, then tumbled by 358.3% to -$240.4 million in 2025, then soared by 66.19% to -$81.3 million in 2026.
- The last three EBITDA figures came in at -$81.3 million (Q1 2026), -$240.4 million (Q4 2025), and -$51.5 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Zenas BioPharma | 1.10 Bn | 379.43 Mn | - | -81.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -81.30 Mn |
| Dec 31, 2025 | -240.44 Mn |
| Sep 30, 2025 | -51.47 Mn |
| Jun 30, 2025 | -52.46 Mn |
| Mar 31, 2025 | -33.63 Mn |
| Dec 31, 2024 | -52.46 Mn |
| Sep 30, 2024 | -38.66 Mn |
| Jun 30, 2024 | -37.95 Mn |
| Mar 31, 2024 | -27.76 Mn |
| Dec 31, 2023 | -24.67 Mn |
| Sep 30, 2023 | 35.62 Mn |