Zenas BioPharma (ZBIO) EBITDA (2023 - 2026)
Zenas BioPharma's (ZBIO) quarterly EBITDA came in at -$77.4 million in Q1 2026, down 107.21% year-on-year from $1.1 billion in Q1 2025, and up 67.5% quarter-over-quarter from -$238.0 million in Q4 2025.
Zenas BioPharma (ZBIO) EBITDA (2023 - 2026) Analysis & Trends
Zenas BioPharma's EBITDA history runs 4 years deep, the most recent figure standing at -$77.4 million for Q1 2026.
- On a quarterly basis, EBITDA fell 107.21% year-over-year to -$77.4 million in Q1 2026; TTM through Mar 2026 was -$423.1 million, a 143.65% decrease from a year earlier, with the FY2025 full-year figure at -$383.1 million, down 133.73% from the prior year.
- EBITDA climbed to -$77.4 million in Q1 2026 per ZBIO's latest filing, from -$238.0 million in the prior quarter.
- Across five years, EBITDA topped out at $35.6 million in Q3 2023 and bottomed at -$238.0 million in Q4 2025.
- The 4-year median for EBITDA is -$41.0 million (2024), against an average of -$55.8 million.
- Biggest YoY gain for EBITDA was 28.29% in 2025; the steepest drop was 327.85% in 2025.
- Year by year, EBITDA stood at -$24.8 million in 2023, then tumbled by 124.48% to -$55.6 million in 2024, then slumped by 327.85% to -$238.0 million in 2025, then jumped by 67.5% to -$77.4 million in 2026.
- Per Business Quant, the three latest ZBIO EBITDA figures stand at -$77.4 million (Q1 2026), -$238.0 million (Q4 2025), and -$52.6 million (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Zenas BioPharma | 1.72 Bn | 1.72 Bn | - | -77.35 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -77.35 Mn |
| Dec 31, 2025 | -237.98 Mn |
| Sep 30, 2025 | -52.58 Mn |
| Jun 30, 2025 | -55.16 Mn |
| Mar 31, 2025 | -37.33 Mn |
| Dec 31, 2024 | -55.62 Mn |
| Sep 30, 2024 | -40.98 Mn |
| Jun 30, 2024 | -39.70 Mn |
| Mar 31, 2024 | -27.58 Mn |
| Dec 31, 2023 | -24.78 Mn |
| Sep 30, 2023 | 35.62 Mn |