111 (YI) Research & Development (2017 - 2025)
111 (YI) reported Research & Development of -$9.0 million for Q4 2025, up 14.02% on a YoY basis from -$7.9 million in Q4 2024, and down 3.32% sequentially from -$8.7 million in Q3 2025.
111 (YI) Research & Development (2017 - 2025) Analysis & Trends
111 (YI) has 9 years of Research & Development data on file, last reported at -$9.0 million in Q4 2025.
- For the quarter ending Q4 2025, Research & Development rose 14.02% year-over-year to -$9.0 million; the trailing twelve-month figure through Dec 2025 stood at -$36.3 million (up 16.85% YoY), and the FY2025 full-year result was $8.6 million, down 9.48% from the prior year.
- Research & Development slipped to -$9.0 million in Q4 2025, from -$8.7 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of -$8.7 million in Q3 2025 to a low of -$24.4 million in Q4 2023.
- A 5-year average of -$14.5 million and a median of -$13.0 million in 2023 frame the typical range for Research & Development.
- Across the five-year window, Research & Development tumbled 79.96% in 2021 and surged 57.3% in 2024, its largest moves.
- Tracing YI's Research & Development over 5 years: stood at -$19.7 million in 2021, then gained by 1.18% to -$19.4 million in 2022, then declined by 25.74% to -$24.4 million in 2023, then surged by 57.3% to -$10.4 million in 2024, then increased by 14.02% to -$9.0 million in 2025.
- Business Quant data shows YI's Research & Development at -$9.0 million in Q4 2025, -$8.7 million in Q3 2025, and -$9.2 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Mckesson | 105.15 Bn | 101.18 Bn | 4.04 Bn | - |
| 2 | Cencora | 60.58 Bn | 58.40 Bn | 3.59 Bn | - |
| 3 | Cardinal Health | 53.81 Bn | 49.87 Bn | 2.50 Bn | - |
| 4 | Henry Schein | 9.71 Bn | 9.57 Bn | 1.07 Bn | - |
| 5 | Akso Health | 3.28 Bn | 3.28 Bn | - | - |
| 6 | 111 | 651.73 Mn | 572.63 Mn | 23.58 Mn | -8.97 Mn |
| 7 | Accendra Health | 248.02 Mn | -88.86 Mn | 278.03 Mn | - |
| 8 | Edap Tms | 230.14 Mn | 215.14 Mn | 8.15 Mn | 2.60 Mn |
| 9 | VitaNova Life Sciences | 11.51 Mn | 11.01 Mn | 316,343.00 | - |
| 10 | Cosmos Health | 9.57 Mn | 7.41 Mn | 1.38 Mn | 19,352.00 |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -8.97 Mn |
| Sep 30, 2025 | -8.69 Mn |
| Jun 30, 2025 | -9.24 Mn |
| Mar 31, 2025 | -9.36 Mn |
| Dec 31, 2024 | -10.44 Mn |
| Sep 30, 2024 | -10.97 Mn |
| Jun 30, 2024 | -11.07 Mn |
| Mar 31, 2024 | -11.13 Mn |
| Dec 31, 2023 | -24.44 Mn |
| Sep 30, 2023 | -13.09 Mn |
| Jun 30, 2023 | -12.43 Mn |
| Mar 31, 2023 | -12.99 Mn |
| Dec 31, 2022 | -19.44 Mn |
| Sep 30, 2022 | -15.15 Mn |
| Jun 30, 2022 | -15.11 Mn |
| Mar 31, 2022 | -18.12 Mn |
| Dec 31, 2021 | -19.67 Mn |
| Sep 30, 2021 | -20.46 Mn |
| Jun 30, 2021 | -20.68 Mn |
| Mar 31, 2021 | -18.69 Mn |