111 (YI) Research & Development (2017 - 2025)
111's (YI) quarterly Research & Development came in at -$2.1 million in Q4 2025, little changed year-on-year from -$2.1 million in Q4 2024, and up 1.68% quarter-over-quarter from -$2.1 million in Q3 2025.
111 (YI) Research & Development (2017 - 2025) Analysis & Trends
111 has disclosed Research & Development across 9 years of filings, most recently posting -$2.1 million for Q4 2025.
- Research & Development for Q4 2025 came in at -$2.1 million, changed 0.05% year-over-year; the trailing twelve-month figure through Dec 2025 was -$8.5 million (up 12.5% YoY), and the FY2025 annual result was $8.6 million, down 9.48% from the prior year.
- Research & Development came in at -$2.1 million for Q4 2025 at 111, up from -$2.1 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of -$2.1 million in Q2 2025 to a low of -$8.7 million in Q3 2021.
- The 5-year median for Research & Development is -$3.6 million (2023), against an average of -$4.3 million.
- Across the five-year window, Research & Development plunged 212.98% in 2021 and surged 69.47% in 2024, its largest moves.
- 111's Research & Development stood at -$4.8 million in 2021, then dropped by 11.39% to -$5.4 million in 2022, then retreated by 28.1% to -$6.9 million in 2023, then soared by 69.47% to -$2.1 million in 2024, then decreased by 0.05% to -$2.1 million in 2025.
- The last three Research & Development figures came in at -$2.1 million (Q4 2025), -$2.1 million (Q3 2025), and -$2.1 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Akso Health | 2,315,158.81 Bn | 2,315,158.63 Bn | - | - |
| 2 | Mckesson | 92.76 Bn | 89.18 Bn | 4.04 Bn | - |
| 3 | Cencora | 52.82 Bn | 50.83 Bn | 3.59 Bn | - |
| 4 | Cardinal Health | 52.17 Bn | 48.39 Bn | 2.50 Bn | - |
| 5 | Henry Schein | 9.19 Bn | 9.71 Bn | 1.07 Bn | - |
| 6 | Accendra Health | 246.88 Mn | -90.00 Mn | 312.39 Mn | - |
| 7 | Edap Tms | 161.92 Mn | 146.92 Mn | 8.15 Mn | 2.60 Mn |
| 8 | 111 | 107.47 Mn | 25.61 Mn | 23.58 Mn | -2.11 Mn |
| 9 | Cosmos Health | 9.42 Mn | 7.26 Mn | 1.38 Mn | - |
| 10 | Cellyan Biotechnology | 5.69 | -2.48 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -2.11 Mn |
| Sep 30, 2025 | -2.15 Mn |
| Jun 30, 2025 | -2.08 Mn |
| Mar 31, 2025 | -2.13 Mn |
| Dec 31, 2024 | -2.11 Mn |
| Sep 30, 2024 | -2.50 Mn |
| Jun 30, 2024 | -2.53 Mn |
| Mar 31, 2024 | -2.54 Mn |
| Dec 31, 2023 | -6.92 Mn |
| Sep 30, 2023 | -3.48 Mn |
| Jun 30, 2023 | -3.38 Mn |
| Mar 31, 2023 | -3.69 Mn |
| Dec 31, 2022 | -5.40 Mn |
| Sep 30, 2022 | -4.15 Mn |
| Jun 30, 2022 | -5.03 Mn |
| Mar 31, 2022 | -6.16 Mn |
| Dec 31, 2021 | -4.85 Mn |
| Sep 30, 2021 | -8.70 Mn |
| Jun 30, 2021 | -8.15 Mn |
| Mar 31, 2021 | -7.59 Mn |