111 (YI) Research & Development (2017 - 2025)
111 (YI) posted Research & Development of -$9.0 million for Q4 2025, down 3.32% sequentially from -$8.7 million in Q3 2025, and up 14.02% YoY from -$7.9 million in Q4 2024.
111 (YI) Research & Development (2017 - 2025) Analysis & Trends
111 has reported Research & Development for 9 years, with the latest figure at -$9.0 million in Q4 2025.
- Quarterly Research & Development rose 14.02% year-over-year to -$9.0 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$36.3 million (up 16.85% YoY) and the FY2025 annual result came in at $8.6 million, down 9.48% from the prior year.
- Research & Development slipped to -$9.0 million in Q4 2025 per YI's latest filing, from -$8.7 million in the prior quarter.
- Over five years, Research & Development peaked at -$8.7 million in Q3 2025 and troughed at -$24.4 million in Q4 2023.
- A 5-year average of -$14.5 million and a median of -$13.0 million in 2023 frame the typical range for Research & Development.
- The sharpest annual moves came in 2021 and 2024: Research & Development sank 79.96% in 2021, then jumped 57.3% in 2024.
- Over 5 years, Research & Development stood at -$19.7 million in 2021, then grew by 1.18% to -$19.4 million in 2022, then decreased by 25.74% to -$24.4 million in 2023, then surged by 57.3% to -$10.4 million in 2024, then advanced by 14.02% to -$9.0 million in 2025.
- According to Business Quant data, Research & Development over the past three periods registered -$9.0 million, -$8.7 million, and -$9.2 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Mckesson | 100.02 Bn | 94.85 Bn | 3.69 Bn | - |
| 2 | Cencora | 60.88 Bn | 58.06 Bn | 3.61 Bn | - |
| 3 | Cardinal Health | 54.14 Bn | 49.29 Bn | 2.56 Bn | - |
| 4 | Henry Schein | 10.05 Bn | 9.90 Bn | 1.10 Bn | - |
| 5 | Akso Health | 737.16 Mn | 736.96 Mn | - | - |
| 6 | Edap Tms | 159.12 Mn | 137.58 Mn | 7.34 Mn | 7.54 Mn |
| 7 | Accendra Health | 100.85 Mn | 93.20 Mn | 263.41 Mn | - |
| 8 | 111 | 32.10 Mn | -26.65 Mn | 18.18 Mn | -8.41 Mn |
| 9 | Cosmos Health | 12.73 Mn | 10.29 Mn | 1.51 Mn | 98,226.00 |
| 10 | VitaNova Life Sciences | 11.51 Mn | 9.91 Mn | 264,662.00 | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -8.97 Mn |
| Sep 30, 2025 | -8.69 Mn |
| Jun 30, 2025 | -9.24 Mn |
| Mar 31, 2025 | -9.36 Mn |
| Dec 31, 2024 | -10.44 Mn |
| Sep 30, 2024 | -10.97 Mn |
| Jun 30, 2024 | -11.07 Mn |
| Mar 31, 2024 | -11.13 Mn |
| Dec 31, 2023 | -24.44 Mn |
| Sep 30, 2023 | -13.09 Mn |
| Jun 30, 2023 | -12.43 Mn |
| Mar 31, 2023 | -12.99 Mn |
| Dec 31, 2022 | -19.44 Mn |
| Sep 30, 2022 | -15.15 Mn |
| Jun 30, 2022 | -15.11 Mn |
| Mar 31, 2022 | -18.12 Mn |
| Dec 31, 2021 | -19.67 Mn |
| Sep 30, 2021 | -20.46 Mn |
| Jun 30, 2021 | -20.68 Mn |
| Mar 31, 2021 | -18.69 Mn |