111 (YI) Operating Margin (2017 - 2025)

111's (YI) quarterly Operating Margin came in at 0.01% in Q4 2025, up 18.0% year-on-year from 0.01% in Q4 2024, and up 85.02% quarter-over-quarter from 0.08% in Q3 2025.

111 (YI) Operating Margin (2017 - 2025) Analysis & Trends

111 has disclosed Operating Margin across 9 years of filings, most recently posting 0.01% for Q4 2025.

  • Operating Margin for Q4 2025 came in at 0.01%, up 18.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 0.02% (down 3.0% YoY), and the FY2025 annual result was 0.02%, down 3.0% from the prior year.
  • Operating Margin came in at 0.01% for Q4 2025 at 111, up from 0.08% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 0.11% in Q1 2024 to a low of 6.68% in Q1 2021.
  • The 5-year median for Operating Margin is 0.89% (2023), against an average of 1.91%.
  • Across the five-year window, Operating Margin surged 545 bps in 2021 and slumped 259 bps in 2022, its largest moves.
  • 111's Operating Margin stood at 0.03% in 2021, then plunged by 10003 bps to 2.61% in 2022, then slumped by 92 bps to 5.03% in 2023, then surged by 96 bps to 0.19% in 2024, then jumped by 94 bps to 0.01% in 2025.
  • The last three Operating Margin figures came in at 0.01% (Q4 2025), 0.08% (Q3 2025), and 0.0% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Akso Health 2,315,158.81 Bn 2,315,158.63 Bn - -
2 Mckesson 92.76 Bn 89.18 Bn 4.04 Bn 2.23%
3 Cencora 52.82 Bn 50.83 Bn 3.59 Bn 1.46%
4 Cardinal Health 52.17 Bn 48.39 Bn 2.50 Bn 0.84%
5 Henry Schein 9.19 Bn 9.71 Bn 1.07 Bn 5.40%
6 Accendra Health 246.88 Mn -90.00 Mn 312.39 Mn 2.73%
7 Edap Tms 161.92 Mn 146.92 Mn 8.15 Mn -41.35%
8 111 107.47 Mn 25.61 Mn 23.58 Mn -0.01%
9 Cosmos Health 9.42 Mn 7.26 Mn 1.38 Mn -12.18%
10 Cellyan Biotechnology 5.69 -2.48 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.08%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 -0.19%
Sep 30, 2024 0.07%
Jun 30, 2024 0.10%
Mar 31, 2024 0.11%
Dec 31, 2023 -5.03%
Sep 30, 2023 -2.19%
Jun 30, 2023 -1.19%
Mar 31, 2023 -0.59%
Dec 31, 2022 -2.61%
Sep 30, 2022 -2.41%
Jun 30, 2022 -2.63%
Mar 31, 2022 -3.42%
Dec 31, 2021 -0.03%
Sep 30, 2021 -5.24%
Jun 30, 2021 -6.24%
Mar 31, 2021 -6.68%