111 (YI) Operating Expenses (2017 - 2025)

111 (YI) reported Operating Expenses of -$403.3 million for Q4 2025, up 23.63% on a YoY basis from -$326.2 million in Q4 2024, and up 4.39% sequentially from -$421.8 million in Q3 2025.

111 (YI) Operating Expenses (2017 - 2025) Analysis & Trends

111 (YI) has 9 years of Operating Expenses data on file, last reported at -$403.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses rose 23.63% year-over-year to -$403.3 million; the trailing twelve-month figure through Dec 2025 stood at -$1.8 billion (up 12.04% YoY), and the FY2025 full-year result was $1.8 billion, down 8.96% from the prior year.
  • Operating Expenses improved to -$403.3 million in Q4 2025, from -$421.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$403.3 million in Q4 2025 to a low of -$617.2 million in Q4 2022.
  • A 5-year average of -$499.2 million and a median of -$487.4 million in 2022 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses plunged 105.05% in 2021 and rose 23.63% in 2025, its largest moves.
  • Tracing YI's Operating Expenses over 5 years: stood at -$559.5 million in 2021, then decreased by 10.3% to -$617.2 million in 2022, then advanced by 1.52% to -$607.8 million in 2023, then climbed by 13.1% to -$528.1 million in 2024, then rose by 23.63% to -$403.3 million in 2025.
  • Business Quant data shows YI's Operating Expenses at -$403.3 million in Q4 2025, -$421.8 million in Q3 2025, and -$447.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Mckesson 105.72 Bn 101.75 Bn 4.04 Bn 1.89 Bn
2 Cencora 60.96 Bn 58.79 Bn 3.59 Bn 2.11 Bn
3 Cardinal Health 53.93 Bn 49.99 Bn 2.50 Bn 1.57 Bn
4 Henry Schein 9.78 Bn 9.65 Bn 1.07 Bn 73.00 Mn
5 Akso Health 3.06 Bn 3.06 Bn - -
6 111 651.73 Mn 572.63 Mn 23.58 Mn -403.32 Mn
7 Accendra Health 247.26 Mn -89.62 Mn 278.03 Mn 610.66 Mn
8 Edap Tms 230.14 Mn 215.14 Mn 8.15 Mn 8.39 Mn
9 VitaNova Life Sciences 11.51 Mn 11.01 Mn 316,343.00 269,612.00
10 Cosmos Health 9.29 Mn 7.13 Mn 1.38 Mn 3.57 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -403.32 Mn
Sep 30, 2025 -421.84 Mn
Jun 30, 2025 -447.49 Mn
Mar 31, 2025 -486.33 Mn
Dec 31, 2024 -528.15 Mn
Sep 30, 2024 -512.76 Mn
Jun 30, 2024 -470.75 Mn
Mar 31, 2024 -488.17 Mn
Dec 31, 2023 -607.78 Mn
Sep 30, 2023 -513.39 Mn
Jun 30, 2023 -485.28 Mn
Mar 31, 2023 -541.45 Mn
Dec 31, 2022 -617.16 Mn
Sep 30, 2022 -482.10 Mn
Jun 30, 2022 -465.34 Mn
Mar 31, 2022 -486.61 Mn
Dec 31, 2021 -559.51 Mn
Sep 30, 2021 -546.54 Mn
Jun 30, 2021 -497.61 Mn
Mar 31, 2021 -422.48 Mn