111 (YI) Operating Expenses (2017 - 2025)

111's (YI) quarterly Operating Expenses came in at -$403.3 million in Q4 2025, up 23.63% year-on-year from -$326.2 million in Q4 2024, and up 4.39% quarter-over-quarter from -$421.8 million in Q3 2025.

111 (YI) Operating Expenses (2017 - 2025) Analysis & Trends

111 has disclosed Operating Expenses across 9 years of filings, most recently posting -$403.3 million for Q4 2025.

  • Operating Expenses for Q4 2025 came in at -$403.3 million, up 23.63% year-over-year; the trailing twelve-month figure through Dec 2025 was -$1.8 billion (up 12.04% YoY), and the FY2025 annual result was $1.8 billion, down 8.96% from the prior year.
  • Operating Expenses came in at -$403.3 million for Q4 2025 at 111, up from -$421.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$403.3 million in Q4 2025 to a low of -$617.2 million in Q4 2022.
  • The 5-year median for Operating Expenses is -$487.4 million (2022), against an average of -$499.2 million.
  • Across the five-year window, Operating Expenses slumped 105.05% in 2021 and rose 23.63% in 2025, its largest moves.
  • 111's Operating Expenses stood at -$559.5 million in 2021, then slipped by 10.3% to -$617.2 million in 2022, then climbed by 1.52% to -$607.8 million in 2023, then grew by 13.1% to -$528.1 million in 2024, then gained by 23.63% to -$403.3 million in 2025.
  • The last three Operating Expenses figures came in at -$403.3 million (Q4 2025), -$421.8 million (Q3 2025), and -$447.5 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Akso Health 2,315,158.81 Bn 2,315,158.63 Bn - -
2 Mckesson 92.76 Bn 89.18 Bn 4.04 Bn 1.89 Bn
3 Cencora 52.82 Bn 50.83 Bn 3.59 Bn 2.11 Bn
4 Cardinal Health 52.17 Bn 48.39 Bn 2.50 Bn 1.57 Bn
5 Henry Schein 9.19 Bn 9.71 Bn 1.07 Bn 162.00 Mn
6 Accendra Health 246.88 Mn -90.00 Mn 312.39 Mn 610.66 Mn
7 Edap Tms 161.92 Mn 146.92 Mn 8.15 Mn 8.39 Mn
8 111 107.47 Mn 25.61 Mn 23.58 Mn -403.32 Mn
9 Cosmos Health 9.42 Mn 7.26 Mn 1.38 Mn 3.57 Mn
10 Cellyan Biotechnology 5.69 -2.48 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -403.32 Mn
Sep 30, 2025 -421.84 Mn
Jun 30, 2025 -447.49 Mn
Mar 31, 2025 -486.33 Mn
Dec 31, 2024 -528.15 Mn
Sep 30, 2024 -512.76 Mn
Jun 30, 2024 -470.75 Mn
Mar 31, 2024 -488.17 Mn
Dec 31, 2023 -607.78 Mn
Sep 30, 2023 -513.39 Mn
Jun 30, 2023 -485.28 Mn
Mar 31, 2023 -541.45 Mn
Dec 31, 2022 -617.16 Mn
Sep 30, 2022 -482.10 Mn
Jun 30, 2022 -465.34 Mn
Mar 31, 2022 -486.61 Mn
Dec 31, 2021 -559.51 Mn
Sep 30, 2021 -546.54 Mn
Jun 30, 2021 -497.61 Mn
Mar 31, 2021 -422.48 Mn