111 (YI) Net Margin (2017 - 2025)

111 (YI) posted Net Margin of 0.58% for Q4 2025, down 33.17% sequentially from 0.43% in Q3 2025, and down 6.0% YoY from 0.61% in Q4 2024.

111 (YI) Net Margin (2017 - 2025) Analysis & Trends

111 has reported Net Margin for 9 years, with the latest figure at 0.58% in Q4 2025.

Quarterly Net Margin fell 6.0% year-over-year to 0.58% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.53% (down 8.0% YoY) and the FY2025 annual result came in at 0.53%, down 8.0% from the prior year.
Net Margin slipped to 0.58% in Q4 2025 per YI's latest filing, from 0.43% in the prior quarter.
Over five years, Net Margin peaked at 0.39% in Q1 2024 and troughed at 7.53% in Q3 2021.
A 5-year average of 2.41% and a median of 2.1% in 2023 frame the typical range for Net Margin.
The sharpest annual moves came in 2021 and 2022: Net Margin slumped 293 bps in 2021, then jumped 463 bps in 2022.
Over 5 years, Net Margin stood at 3.23% in 2021, then advanced by 15 bps to 2.76% in 2022, then plunged by 86 bps to 5.12% in 2023, then soared by 90 bps to 0.52% in 2024, then decreased by 12 bps to 0.58% in 2025.
According to Business Quant data, Net Margin over the past three periods registered 0.58%, 0.43%, and 0.61% for Q4 2025, Q3 2025, and Q2 2025 respectively.

#	Company	Market Cap	Enterprise Value	Gross Profit (Qtr)	Net Margin (Qtr)
1	Mckesson	100.02 Bn	94.85 Bn	3.69 Bn	0.98%
2	Cencora	60.88 Bn	58.06 Bn	3.61 Bn	0.92%
3	Cardinal Health	54.14 Bn	49.29 Bn	2.56 Bn	0.63%
4	Henry Schein	10.05 Bn	9.90 Bn	1.10 Bn	2.98%
5	Akso Health	737.16 Mn	736.96 Mn	-	-
6	Edap Tms	159.12 Mn	137.58 Mn	7.34 Mn	-109.73%
7	Accendra Health	100.85 Mn	93.20 Mn	263.41 Mn	-14.52%
8	111	32.10 Mn	-26.65 Mn	18.18 Mn	-1.57%
9	Cosmos Health	12.73 Mn	10.29 Mn	1.51 Mn	-32.06%
10	VitaNova Life Sciences	11.51 Mn	9.91 Mn	264,662.00	0.98%

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