111 (YI) Gross Profit (2017 - 2025)

111's (YI) quarterly Gross Profit came in at $23.6 million in Q4 2025, down 15.0% year-on-year from $27.7 million in Q4 2024, and down 5.2% quarter-over-quarter from $24.9 million in Q3 2025.

111 (YI) Gross Profit (2017 - 2025) Analysis & Trends

111 has disclosed Gross Profit across 9 years of filings, most recently posting $23.6 million for Q4 2025.

  • Gross Profit for Q4 2025 came in at $23.6 million, down 15.0% year-over-year; the trailing twelve-month figure through Dec 2025 was $100.9 million (down 12.39% YoY), and the FY2025 annual result was $1.7 billion, up 1406.3% from the prior year.
  • Gross Profit came in at $23.6 million for Q4 2025 at 111, down from $24.9 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $62.8 billion in Q4 2021 to a low of $17.9 million in Q1 2021.
  • The 5-year median for Gross Profit is $28.5 million (2022), against an average of $3.2 billion.
  • Across the five-year window, Gross Profit jumped 16129.36% in 2021 and tumbled 99.94% in 2022, its largest moves.
  • 111's Gross Profit stood at $62.8 billion in 2021, then sank by 99.94% to $36.8 million in 2022, then declined by 17.89% to $30.2 million in 2023, then retreated by 8.08% to $27.7 million in 2024, then dropped by 15.0% to $23.6 million in 2025.
  • The last three Gross Profit figures came in at $23.6 million (Q4 2025), $24.9 million (Q3 2025), and $25.6 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Akso Health 2,315,158.81 Bn 2,315,158.63 Bn -
2 Mckesson 92.76 Bn 89.18 Bn 4.04 Bn
3 Cencora 52.82 Bn 50.83 Bn 3.59 Bn
4 Cardinal Health 52.17 Bn 48.39 Bn 2.50 Bn
5 Henry Schein 9.19 Bn 9.71 Bn 1.07 Bn
6 Accendra Health 246.88 Mn -90.00 Mn 312.39 Mn
7 Edap Tms 161.92 Mn 146.92 Mn 8.15 Mn
8 111 107.47 Mn 25.61 Mn 23.58 Mn
9 Cosmos Health 9.42 Mn 7.26 Mn 1.38 Mn
10 Cellyan Biotechnology 5.69 -2.48 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 23.58 Mn
Dec 31, 2025 23.58 Mn
Sep 30, 2025 24.87 Mn
Sep 30, 2025 24.87 Mn
Jun 30, 2025 25.63 Mn
Jun 30, 2025 25.63 Mn
Mar 31, 2025 26.84 Mn
Mar 31, 2025 26.84 Mn
Dec 31, 2024 27.74 Mn
Dec 31, 2024 27.74 Mn
Sep 30, 2024 30.01 Mn
Sep 30, 2024 30.01 Mn
Jun 30, 2024 28.57 Mn
Jun 30, 2024 28.57 Mn
Mar 31, 2024 28.88 Mn
Mar 31, 2024 28.88 Mn
Dec 31, 2023 30.18 Mn
Dec 31, 2023 30.18 Mn
Sep 30, 2023 26.13 Mn
Sep 30, 2023 26.13 Mn