111 (YI) Gross Margin (2017 - 2025)
111's (YI) quarterly Gross Margin came in at 5.85% in Q4 2025, up 58.0% year-on-year from 3.7% in Q4 2024, and down 0.92% quarter-over-quarter from 5.9% in Q3 2025.
111 (YI) Gross Margin (2017 - 2025) Analysis & Trends
111 has disclosed Gross Margin across 9 years of filings, most recently posting 5.85% for Q4 2025.
- Gross Margin for Q4 2025 came in at 5.85%, up 58.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 5.74% (down 2.0% YoY), and the FY2025 annual result was 95.31%, up 8955.0% from the prior year.
- Gross Margin came in at 5.85% for Q4 2025 at 111, down from 5.9% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 99.2% in Q4 2021 to a low of 4.45% in Q2 2021.
- The 5-year median for Gross Margin is 5.88% (2025), against an average of 10.34%.
- Across the five-year window, Gross Margin surged 368 bps in 2021 and tumbled 9308 bps in 2022, its largest moves.
- 111's Gross Margin stood at 99.2% in 2021, then slumped by 94 bps to 6.11% in 2022, then declined by 15 bps to 5.21% in 2023, then gained by 1 bps to 5.26% in 2024, then rose by 11 bps to 5.85% in 2025.
- The last three Gross Margin figures came in at 5.85% (Q4 2025), 5.9% (Q3 2025), and 5.73% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Akso Health | 2,315,158.81 Bn | 2,315,158.63 Bn | - | - |
| 2 | Mckesson | 92.76 Bn | 89.18 Bn | 4.04 Bn | 4.20% |
| 3 | Cencora | 52.82 Bn | 50.83 Bn | 3.59 Bn | 4.58% |
| 4 | Cardinal Health | 52.17 Bn | 48.39 Bn | 2.50 Bn | 4.10% |
| 5 | Henry Schein | 9.19 Bn | 9.71 Bn | 1.07 Bn | 31.77% |
| 6 | Accendra Health | 246.88 Mn | -90.00 Mn | 312.39 Mn | 49.76% |
| 7 | Edap Tms | 161.92 Mn | 146.92 Mn | 8.15 Mn | 45.73% |
| 8 | 111 | 107.47 Mn | 25.61 Mn | 23.58 Mn | 5.85% |
| 9 | Cosmos Health | 9.42 Mn | 7.26 Mn | 1.38 Mn | 7.70% |
| 10 | Cellyan Biotechnology | 5.69 | -2.48 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 5.85% |
| Sep 30, 2025 | 5.90% |
| Jun 30, 2025 | 5.73% |
| Mar 31, 2025 | 5.52% |
| Dec 31, 2024 | 5.26% |
| Sep 30, 2024 | 5.85% |
| Jun 30, 2024 | 6.06% |
| Mar 31, 2024 | 5.91% |
| Dec 31, 2023 | 5.21% |
| Sep 30, 2023 | 5.20% |
| Jun 30, 2023 | 5.98% |
| Mar 31, 2023 | 6.39% |
| Dec 31, 2022 | 6.11% |
| Sep 30, 2022 | 6.03% |
| Jun 30, 2022 | 6.32% |
| Mar 31, 2022 | 6.45% |
| Dec 31, 2021 | 99.20% |
| Sep 30, 2021 | 4.96% |
| Jun 30, 2021 | 4.45% |
| Mar 31, 2021 | 4.51% |