111 (YI) Gross Margin (2017 - 2025)
111 (YI) reported Gross Margin of 5.85% for Q4 2025, up 58.0% on a YoY basis from 3.7% in Q4 2024, and down 0.92% sequentially from 5.9% in Q3 2025.
111 (YI) Gross Margin (2017 - 2025) Analysis & Trends
111 (YI) has 9 years of Gross Margin data on file, last reported at 5.85% in Q4 2025.
- For the quarter ending Q4 2025, Gross Margin rose 58.0% year-over-year to 5.85%; the trailing twelve-month figure through Dec 2025 stood at 5.74% (down 1.0% YoY), and the FY2025 full-year result was 5.61%, down 15.0% from the prior year.
- Gross Margin fell to 5.85% in Q4 2025, from 5.9% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 6.46% in Q1 2022 to a low of 4.45% in Q2 2021.
- A 5-year average of 5.7% and a median of 5.87% in 2025 frame the typical range for Gross Margin.
- Peak annual rise in Gross Margin reached 200 bps in 2021, while the deepest fall reached 113 bps in 2021.
- Tracing YI's Gross Margin over 5 years: stood at 5.91% in 2021, then climbed by 3 bps to 6.11% in 2022, then dropped by 15 bps to 5.21% in 2023, then rose by 1 bps to 5.26% in 2024, then increased by 11 bps to 5.85% in 2025.
- Business Quant data shows YI's Gross Margin at 5.85% in Q4 2025, 5.9% in Q3 2025, and 5.73% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Mckesson | 105.45 Bn | 101.48 Bn | 4.04 Bn | 4.20% |
| 2 | Cencora | 60.61 Bn | 58.43 Bn | 3.59 Bn | 4.58% |
| 3 | Cardinal Health | 53.92 Bn | 49.99 Bn | 2.50 Bn | 4.10% |
| 4 | Henry Schein | 9.73 Bn | 9.59 Bn | 1.07 Bn | 31.77% |
| 5 | Akso Health | 3.28 Bn | 3.28 Bn | - | - |
| 6 | 111 | 651.73 Mn | 572.63 Mn | 23.58 Mn | 5.85% |
| 7 | Accendra Health | 246.88 Mn | -90.00 Mn | 278.03 Mn | 44.29% |
| 8 | Edap Tms | 228.64 Mn | 213.64 Mn | 8.15 Mn | 45.73% |
| 9 | VitaNova Life Sciences | 11.51 Mn | 11.01 Mn | 316,343.00 | 44.58% |
| 10 | Cosmos Health | 9.58 Mn | 7.42 Mn | 1.38 Mn | 7.70% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 5.85% |
| Sep 30, 2025 | 5.90% |
| Jun 30, 2025 | 5.73% |
| Mar 31, 2025 | 5.52% |
| Dec 31, 2024 | 5.26% |
| Sep 30, 2024 | 5.73% |
| Jun 30, 2024 | 6.09% |
| Mar 31, 2024 | 5.97% |
| Dec 31, 2023 | 5.21% |
| Sep 30, 2023 | 5.25% |
| Jun 30, 2023 | 5.98% |
| Mar 31, 2023 | 6.39% |
| Dec 31, 2022 | 6.11% |
| Sep 30, 2022 | 6.27% |
| Jun 30, 2022 | 6.42% |
| Mar 31, 2022 | 6.46% |
| Dec 31, 2021 | 5.91% |
| Sep 30, 2021 | 4.96% |
| Jun 30, 2021 | 4.45% |
| Mar 31, 2021 | 4.51% |