XORTX Therapeutics (XRTX) Return on Equity [ROE] (2021 - 2026)
XORTX Therapeutics' Return on Equity [ROE] was 10.54% in the quarter ended Jun 30, 2026, up 152.60 percentage points from -142.06% a year earlier but down 58.25 percentage points from the prior quarter.
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Analysis
XORTX Therapeutics (XRTX) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Return on Equity [ROE] at XORTX Therapeutics came in at -98.00%, down 14.94 percentage points from the prior year.
- Return on Equity [ROE] shows a five-year change of -408.63 percentage points (years ended Dec 2020 to Dec 2025).
- In earlier years, Return on Equity [ROE] was -83.06% in the year ended Dec 31, 2024 (-45.97 pp), -37.08% in the year ended Dec 31, 2023 (+39.34 pp), -76.43% in the year ended Dec 31, 2022 (-57.84 pp) and -18.58% in the year ended Dec 31, 2021 (-329.22 pp).
- Quarterly Return on Equity [ROE] has moved between -142.06% (the quarter ended Jun 30, 2025) and 68.79% (the quarter ended Mar 31, 2026) over five years.
- Compared with a year earlier, Return on Equity [ROE] has increased for three straight quarters, with an average year-over-year change of +32.74 percentage points over the last eight quarters.
- The best year-over-year quarter for Return on Equity [ROE] over five years was the quarter ended Jun 30, 2026 (a gain of 152.60 percentage points); the worst was the quarter ended Dec 31, 2022 (a drop of 102.07 percentage points).
- Per Business Quant data, XRTX's Return on Equity [ROE] in the three quarters before the quarter ended Jun 30, 2026 was 68.79% (quarter ended Mar 31, 2026), -30.23% (quarter ended Dec 31, 2025) and -93.16% (quarter ended Sep 30, 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | XORTX Therapeutics | 1.60 Mn | -1.70 Mn | - | 10.54% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 10.54% |
| Mar 31, 2026 | 68.79% |
| Dec 31, 2025 | -30.23% |
| Sep 30, 2025 | -93.16% |
| Jun 30, 2025 | -142.06% |
| Mar 31, 2025 | -76.65% |
| Dec 31, 2024 | -131.00% |
| Sep 30, 2024 | -37.30% |
| Jun 30, 2024 | -52.39% |
| Mar 31, 2024 | -90.36% |
| Dec 31, 2023 | -52.91% |
| Sep 30, 2023 | -110.30% |
| Jun 30, 2023 | -88.72% |
| Mar 31, 2023 | -103.08% |
| Dec 31, 2022 | -122.58% |
| Sep 30, 2022 | -89.86% |
| Jun 30, 2022 | -70.63% |
| Mar 31, 2022 | -39.33% |
| Dec 31, 2021 | -20.51% |
API Access
XORTX Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XRTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();