Xilio Therapeutics (XLO) Return on Capital Employed [ROCE] (2021 - 2026)
Xilio Therapeutics (XLO) recorded Return on Capital Employed [ROCE] of -25.16% in Q2 2026, up 61.26 percentage points from -86.42% a year earlier and up 11.22 percentage points from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) Return on Capital Employed [ROCE] (2021 - 2026) Analysis & Trends
For FY2025, Xilio Therapeutics reported Return on Capital Employed [ROCE] of -74.16%, up 82.22 percentage points from FY2024.
- Annual Return on Capital Employed [ROCE] has a four-year change of -8.57 percentage points (FY2021 to FY2025).
- Across earlier years, Return on Capital Employed [ROCE] came in at -156.38% in FY2024 (-62.28 pp), -94.11% in FY2023 (-37.50 pp), -56.60% in FY2022 (+8.99 pp) and -65.59% in FY2021.
- The Q2 2026 figure is the highest quarterly Return on Capital Employed [ROCE] in data going back to Q4 2021.
- On a year-over-year basis, Return on Capital Employed [ROCE] has increased for seven consecutive quarters, with an average year-over-year change of +53.72 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Capital Employed [ROCE] in the last five years was a gain of 106.85 percentage points in Q1 2026, against a drop of 98.10 percentage points in Q1 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -36.38% (Q1 2026), -47.75% (Q4 2025) and -56.59% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,199.50 Bn | 1,168.08 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 635.17 Bn | 555.03 Bn | 17.30 Bn | 17.52% |
| 3 | AbbVie | 504.69 Bn | 477.85 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 358.43 Bn | 312.86 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 288.36 Bn | 252.75 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 265.78 Bn | 239.54 Bn | 12.86 Bn | 16.76% |
| 7 | Amgen | 237.46 Bn | 192.86 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 193.65 Bn | 167.76 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 171.05 Bn | 118.00 Bn | 10.94 Bn | 11.86% |
| 10 | Xilio Therapeutics | 146.89 Mn | -380.77 Mn | - | -25.16% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -25.16% |
| Mar 31, 2026 | -36.38% |
| Dec 31, 2025 | -47.75% |
| Sep 30, 2025 | -56.59% |
| Jun 30, 2025 | -86.42% |
| Mar 31, 2025 | -143.23% |
| Dec 31, 2024 | -132.84% |
| Sep 30, 2024 | -147.10% |
| Jun 30, 2024 | -142.19% |
| Mar 31, 2024 | -181.89% |
| Dec 31, 2023 | -148.11% |
| Sep 30, 2023 | -123.47% |
| Jun 30, 2023 | -101.61% |
| Mar 31, 2023 | -83.79% |
| Dec 31, 2022 | -70.10% |
| Sep 30, 2022 | -56.67% |
| Jun 30, 2022 | -47.97% |
| Mar 31, 2022 | -40.90% |
| Dec 31, 2021 | -47.92% |
API Access
Xilio Therapeutics Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();