Xilio Therapeutics (XLO) Return on Assets [ROA] (2021 - 2026)
Xilio Therapeutics' Return on Assets [ROA] was -19.74% in Q2 2026, up 27.92 percentage points from -47.66% a year earlier and up 6.81 percentage points from the prior quarter.
Powered by 
Analysis
Xilio Therapeutics (XLO) Return on Assets [ROA] (2021 - 2026) Analysis & Trends
For FY2025, Return on Assets [ROA] at Xilio Therapeutics came in at -37.19%, up 54.60 percentage points from FY2024.
- Return on Assets [ROA] shows a four-year change of +21.81 percentage points (FY2021 to FY2025).
- In earlier years, Return on Assets [ROA] was -91.79% in FY2024 (-12.69 pp), -79.10% in FY2023 (-29.19 pp), -49.91% in FY2022 (+9.09 pp) and -59.00% in FY2021.
- The Q2 2026 figure marks the highest quarterly Return on Assets [ROA] in data going back to Q4 2021.
- Compared with a year earlier, Return on Assets [ROA] has increased for nine straight quarters, with an average year-over-year change of +35.64 percentage points over the last eight quarters.
- The best year-over-year quarter for Return on Assets [ROA] over five years was Q4 2025 (a gain of 54.03 percentage points); the worst was Q4 2023 (a drop of 53.93 percentage points).
- Per Business Quant data, XLO's Return on Assets [ROA] in the three quarters before Q2 2026 was -26.55% (Q1 2026), -29.12% (Q4 2025) and -32.73% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,137.66 Bn | 1,106.24 Bn | 19.71 Bn | 20.64% |
| 2 | Johnson & Johnson | 636.13 Bn | 556.00 Bn | 17.30 Bn | 8.08% |
| 3 | AbbVie | 505.28 Bn | 478.39 Bn | 12.70 Bn | 4.65% |
| 4 | Merck | 358.10 Bn | 312.48 Bn | 12.21 Bn | 2.45% |
| 5 | Novartis Ag | 292.59 Bn | 256.58 Bn | 11.24 Bn | 10.60% |
| 6 | Astrazeneca | 265.81 Bn | 239.50 Bn | 12.86 Bn | 9.10% |
| 7 | Amgen | 237.53 Bn | 192.93 Bn | 7.24 Bn | 9.29% |
| 8 | Gilead Sciences | 194.67 Bn | 168.86 Bn | 6.22 Bn | -6.13% |
| 9 | Pfizer | 171.17 Bn | 117.82 Bn | 10.94 Bn | 2.14% |
| 10 | Xilio Therapeutics | 153.30 Mn | -374.37 Mn | - | -19.74% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -19.74% |
| Mar 31, 2026 | -26.55% |
| Dec 31, 2025 | -29.12% |
| Sep 30, 2025 | -32.73% |
| Jun 30, 2025 | -47.66% |
| Mar 31, 2025 | -65.16% |
| Dec 31, 2024 | -83.14% |
| Sep 30, 2024 | -79.11% |
| Jun 30, 2024 | -78.48% |
| Mar 31, 2024 | -101.85% |
| Dec 31, 2023 | -114.05% |
| Sep 30, 2023 | -98.91% |
| Jun 30, 2023 | -85.37% |
| Mar 31, 2023 | -72.97% |
| Dec 31, 2022 | -60.12% |
| Sep 30, 2022 | -50.99% |
| Jun 30, 2022 | -43.42% |
| Mar 31, 2022 | -38.49% |
| Dec 31, 2021 | -44.30% |
API Access
Xilio Therapeutics Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();