X4 Pharmaceuticals (XFOR) Return on Invested Capital (2020 - 2025)
X4 Pharmaceuticals (XFOR) reported Return on Invested Capital of 0.0% for Q4 2025, little changed on a YoY basis from 0.0% in Q4 2024, and up 52.53% quarter-over-quarter from 0.01% in Q3 2025.
X4 Pharmaceuticals (XFOR) Return on Invested Capital (2020 - 2025) Analysis & Trends
X4 Pharmaceuticals has reported Return on Invested Capital for 6 years, with the latest figure at 0.0% in Q4 2025.
- For the quarter ending Q4 2025, Return on Invested Capital changed 0.0% year-over-year to 0.0%; the trailing twelve-month figure through Dec 2025 stood at 0.0% (changed 0.0% YoY), and the FY2025 full-year result was 0.0%, changed 0.0% from the prior year.
- Return on Invested Capital for Q4 2025 stood at 0.0%, up from 0.01% in the prior quarter.
- The five-year high for Return on Invested Capital was 0.0% in Q1 2025, with the low at 0.01% in Q1 2024.
- Historically, Return on Invested Capital has averaged 0.01% across 5 years, with a median of 0.01% in 2025.
- Annual changes were most pronounced in 2022 — Return on Invested Capital slipped 1 bps — and 2024, when it gained 1 bps.
- X4 Pharmaceuticals' Return on Invested Capital stood at 0.01% in 2021, then declined by 1 bps to 0.01% in 2022, then slipped by 8 bps to 0.01% in 2023, then surged by 66 bps to 0.0% in 2024, then slumped by 38 bps to 0.0% in 2025.
- The last three Return on Invested Capital figures came in at 0.0% (Q4 2025), 0.01% (Q3 2025), and 0.01% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | - |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | 0.01% |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | -0.01% |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | -0.01% |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 0.00% |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | - |
| 10 | X4 Pharmaceuticals | 166.63 Mn | 166.63 Mn | 2.20 Mn | 0.00% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 0.00% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | -0.01% |
| Mar 31, 2025 | 0.00% |
| Dec 31, 2024 | 0.00% |
| Sep 30, 2024 | 0.00% |
| Jun 30, 2024 | 0.00% |
| Mar 31, 2024 | -0.01% |
| Dec 31, 2023 | -0.01% |
| Sep 30, 2023 | -0.01% |
| Jun 30, 2023 | -0.01% |
| Mar 31, 2023 | -0.01% |
| Dec 31, 2022 | -0.01% |
| Sep 30, 2022 | -0.01% |
| Jun 30, 2022 | -0.01% |
| Mar 31, 2022 | -0.01% |
| Dec 31, 2021 | -0.01% |
| Sep 30, 2021 | -0.01% |
| Jun 30, 2021 | -0.01% |
| Mar 31, 2021 | -0.01% |