X4 Pharmaceuticals (XFOR) Return on Invested Capital (2020 - 2025)

X4 Pharmaceuticals (XFOR) reported Return on Invested Capital of 0.0% for Q4 2025, little changed on a YoY basis from 0.0% in Q4 2024, and up 52.53% quarter-over-quarter from 0.01% in Q3 2025.

X4 Pharmaceuticals (XFOR) Return on Invested Capital (2020 - 2025) Analysis & Trends

X4 Pharmaceuticals has reported Return on Invested Capital for 6 years, with the latest figure at 0.0% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Invested Capital changed 0.0% year-over-year to 0.0%; the trailing twelve-month figure through Dec 2025 stood at 0.0% (changed 0.0% YoY), and the FY2025 full-year result was 0.0%, changed 0.0% from the prior year.
  • Return on Invested Capital for Q4 2025 stood at 0.0%, up from 0.01% in the prior quarter.
  • The five-year high for Return on Invested Capital was 0.0% in Q1 2025, with the low at 0.01% in Q1 2024.
  • Historically, Return on Invested Capital has averaged 0.01% across 5 years, with a median of 0.01% in 2025.
  • Annual changes were most pronounced in 2022 — Return on Invested Capital slipped 1 bps — and 2024, when it gained 1 bps.
  • X4 Pharmaceuticals' Return on Invested Capital stood at 0.01% in 2021, then declined by 1 bps to 0.01% in 2022, then slipped by 8 bps to 0.01% in 2023, then surged by 66 bps to 0.0% in 2024, then slumped by 38 bps to 0.0% in 2025.
  • The last three Return on Invested Capital figures came in at 0.0% (Q4 2025), 0.01% (Q3 2025), and 0.01% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROIC (Qtr)
1 Alterity Therapeutics 788,338.31 Bn 788,338.28 Bn - -
2 Belite Bio 56,560.00 Bn 56,560.00 Bn - -
3 Quantum Biopharma 17,329.30 Bn 17,329.30 Bn - -
4 Legend Biotech 3,341.00 Bn 3,340.71 Bn 242.10 Mn 0.01%
5 Akari Therapeutics 1,727.91 Bn 1,727.91 Bn - -0.01%
6 Evaxion A 1,536.68 Bn 1,536.67 Bn - -0.01%
7 Psyence Biomedical 238.34 Bn 238.33 Bn - -
8 Vertex Pharmaceuticals 113.42 Bn 106.17 Bn 2.59 Bn 0.00%
9 Abivax 95.45 Bn 95.45 Bn - -
10 X4 Pharmaceuticals 166.63 Mn 166.63 Mn 2.20 Mn 0.00%

Historic Data

Download Data
DateValue
Dec 31, 2025 0.00%
Sep 30, 2025 -0.01%
Jun 30, 2025 -0.01%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%
Mar 31, 2024 -0.01%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 -0.01%
Mar 31, 2023 -0.01%
Dec 31, 2022 -0.01%
Sep 30, 2022 -0.01%
Jun 30, 2022 -0.01%
Mar 31, 2022 -0.01%
Dec 31, 2021 -0.01%
Sep 30, 2021 -0.01%
Jun 30, 2021 -0.01%
Mar 31, 2021 -0.01%