X4 Pharmaceuticals, Inc (XFOR) Institutional Ownership

Ownership Summary

According to SEC filings for the period ending December 2025, X4 Pharmaceuticals, Inc (NASDAQ:XFOR) is held by 77 institutional firms.

• The collective stake of institutional investors in X4 Pharmaceuticals moved to 951.4% in December 2025, a shift up from the 172.0% reported for September 2025.
• In percentage terms, this reflects as a holdings change of 501.71% quarter on quarter, and a decrease of 14.44% year over year.
• Of these 77 institutional investors, 58 increased their holdings in X4 Pharmaceuticals, while 8 of them reduced positions, and 11 investors maintained their exposure.
• This class of investors increased its holdings in X4 Pharmaceuticals to 89.40Mn shares for the 13F-cycle ending December 2025, up by 74.55Mn shares quarter on quarter, and up 86.08Mn shares year over year.
• Empery Asset Management, LP continues to be the largest institutional holder of X4 Pharmaceuticals as of December 31, 2025, with a position of 8.95Mn shares, representing 95.26% of the company's outstanding stock.
• Among the most significant buyers of X4 Pharmaceuticals during December 2025 were Empery Asset Management, LP (8.95Mn), FMR LLC (8.50Mn), MORGAN STANLEY (8.20Mn), PERCEPTIVE ADVISORS LLC (6.31Mn), Saturn V Capital Management LP (5.80Mn).
• Leading sellers of X4 Pharmaceuticals stock in December 2025 included Stonepine Capital Management, LLC (462.76K), UBS Group AG (155.71K), Pale Fire Capital SE (13.26K), MILLENNIUM MANAGEMENT LLC (8.82K), ROYAL BANK OF CANADA (2.43K).
• The top 10 institutional holders of X4 Pharmaceuticals for the quarter ending December 2025 included Empery Asset Management, LP (8.95Mn), FMR LLC (8.50Mn), MORGAN STANLEY (8.21Mn), Bain Capital Life Sciences Investors, LLC (7.97Mn), PERCEPTIVE ADVISORS LLC (6.31Mn), Saturn V Capital Management LP (5.80Mn), Deep Track Capital, LP (5.01Mn), Kalehua Capital Management LLC (3.72Mn), VANGUARD GROUP INC (3.42Mn), BRAIDWELL LP (3.37Mn).