X4 Pharmaceuticals (XFOR) Return on Equity [ROE] (2019 - 2026)
X4 Pharmaceuticals (XFOR) recorded Return on Equity [ROE] of -55.66% in Q2 2026, up 702.11 percentage points from -757.76% a year earlier and up 0.57 percentage points from the prior quarter.
X4 Pharmaceuticals (XFOR) Return on Equity [ROE] (2019 - 2026) Analysis & Trends
For FY2025, X4 Pharmaceuticals reported Return on Equity [ROE] of -75.99%, up 26.26 percentage points from FY2024.
- Annual Return on Equity [ROE] has a five-year change of -14.48 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -102.26% in FY2024 (+59.42 pp), -161.67% in FY2023 (-26.09 pp), -135.58% in FY2022 (-6.30 pp) and -129.28% in FY2021 (-67.77 pp).
- The Q2 2026 figure is the highest quarterly Return on Equity [ROE] since Q1 2025.
- On a year-over-year basis, Return on Equity [ROE] rose in five of the last eight quarters, with an average year-over-year change of +40.85 percentage points.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 702.11 percentage points in Q2 2026, against a drop of 794.69 percentage points in Q2 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -56.22% (Q1 2026), -63.89% (Q4 2025) and -289.97% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | X4 Pharmaceuticals | 366.40 Mn | -332.29 Mn | 7.19 Mn | -55.66% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -55.66% |
| Mar 31, 2026 | -56.22% |
| Dec 31, 2025 | -63.89% |
| Sep 30, 2025 | -289.97% |
| Jun 30, 2025 | -757.76% |
| Mar 31, 2025 | 64.75% |
| Dec 31, 2024 | -91.60% |
| Sep 30, 2024 | -21.75% |
| Jun 30, 2024 | 36.93% |
| Mar 31, 2024 | -494.54% |
| Dec 31, 2023 | -170.47% |
| Sep 30, 2023 | -164.50% |
| Jun 30, 2023 | -218.81% |
| Mar 31, 2023 | -152.59% |
| Dec 31, 2022 | -138.14% |
| Sep 30, 2022 | -206.63% |
| Jun 30, 2022 | -234.52% |
| Mar 31, 2022 | -161.20% |
| Dec 31, 2021 | -133.29% |
| Sep 30, 2021 | -98.56% |
X4 Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XFOR&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XFOR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XFOR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();