X4 Pharmaceuticals (XFOR) Net Income (2017 - 2025)

X4 Pharmaceuticals posted quarterly Net Income of -$23.9 million for Q4 2025, up 39.92% year-on-year from -$17.1 million in Q4 2024, and up 19.76% on a QoQ basis from -$29.8 million in Q3 2025.

X4 Pharmaceuticals (XFOR) has 9 years of Net Income data on file, last reported at -$23.9 million in Q4 2025.

  • For the quarter ending Q4 2025, Net Income rose 39.92% year-over-year to -$23.9 million; the trailing twelve-month figure through Dec 2025 stood at -$79.2 million (down 111.48% YoY), and the FY2025 full-year result was -$79.2 million, down 111.48% from the prior year.
  • Net Income for Q4 2025 stood at -$23.9 million, up from -$29.8 million in the prior quarter.
  • Across five years, Net Income topped out at $90.8 million in Q2 2024 and bottomed at -$55.7 million in Q2 2023.
  • The 5-year median for Net Income is -$22.9 million (2022), against an average of -$20.0 million.
  • Peak annual rise in Net Income reached 263.04% in 2024, while the deepest fall reached 1492.02% in 2024.
  • A 5-year view of Net Income shows it stood at -$30.2 million in 2021, then grew by 3.65% to -$29.1 million in 2022, then soared by 34.27% to -$19.1 million in 2023, then plunged by 108.16% to -$39.8 million in 2024, then soared by 39.92% to -$23.9 million in 2025.
  • The last three Net Income figures came in at -$23.9 million (Q4 2025), -$29.8 million (Q3 2025), and -$25.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.99 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -8.40 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.40 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 205.99 Mn
10 X4 Pharmaceuticals 182.28 Mn 182.28 Mn 2.20 Mn -23.93 Mn

Historic Data

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DateValue
Dec 31, 2025 -23.93 Mn
Sep 30, 2025 -29.82 Mn
Jun 30, 2025 -25.74 Mn
Mar 31, 2025 282,000.00
Dec 31, 2024 -39.82 Mn
Sep 30, 2024 -36.70 Mn
Jun 30, 2024 90.83 Mn
Mar 31, 2024 -51.77 Mn
Dec 31, 2023 -19.13 Mn
Sep 30, 2023 -2.31 Mn
Jun 30, 2023 -55.71 Mn
Mar 31, 2023 -24.02 Mn
Dec 31, 2022 -29.10 Mn
Sep 30, 2022 -21.59 Mn
Jun 30, 2022 -21.21 Mn
Mar 31, 2022 -21.97 Mn
Dec 31, 2021 -30.21 Mn
Sep 30, 2021 -20.18 Mn
Jun 30, 2021 -19.64 Mn
Mar 31, 2021 -18.68 Mn
Dec 31, 2020 -18.40 Mn
Sep 30, 2020 -17.45 Mn
Jun 30, 2020 -15.14 Mn
Mar 31, 2020 -11.14 Mn
Dec 31, 2019 -10.84 Mn
Sep 30, 2019 -17.71 Mn
Jun 30, 2019 -13.38 Mn
Mar 31, 2019 -10.87 Mn
Dec 31, 2018 -8.24 Mn
Sep 30, 2018 -8.64 Mn
Jun 30, 2018 -6.48 Mn
Mar 31, 2018 -6.21 Mn
Dec 31, 2017 3.57 Mn
Sep 30, 2017 -13.31 Mn
Jun 30, 2017 -6.09 Mn
Mar 31, 2017 -6.85 Mn