X4 Pharmaceuticals (XFOR) EBIT (2017 - 2025)
X4 Pharmaceuticals (XFOR) reported EBIT of -$23.7 million for Q4 2025, up 33.64% on a YoY basis from -$17.7 million in Q4 2024, and up 13.85% quarter-over-quarter from -$27.5 million in Q3 2025.
X4 Pharmaceuticals (XFOR) EBIT (2017 - 2025) Analysis & Trends
X4 Pharmaceuticals has reported EBIT for 9 years, with the latest figure at -$23.7 million in Q4 2025.
- For the quarter ending Q4 2025, EBIT rose 33.64% year-over-year to -$23.7 million; the trailing twelve-month figure through Dec 2025 stood at -$86.9 million (down 138.68% YoY), and the FY2025 full-year result was -$86.9 million, down 138.68% from the prior year.
- EBIT for Q4 2025 stood at -$23.7 million, up from -$27.5 million in the prior quarter.
- The five-year high for EBIT was $71.1 million in Q2 2024, with the low at -$37.3 million in Q1 2024.
- Historically, EBIT has averaged -$20.2 million across 5 years, with a median of -$25.4 million in 2022.
- Annual changes were most pronounced in 2024 — EBIT surged 375.54% — and 2025, when it slumped 136.89%.
- X4 Pharmaceuticals' EBIT stood at -$29.1 million in 2021, then grew by 11.97% to -$25.6 million in 2022, then grew by 1.48% to -$25.2 million in 2023, then sank by 41.73% to -$35.7 million in 2024, then soared by 33.64% to -$23.7 million in 2025.
- The last three EBIT figures came in at -$23.7 million (Q4 2025), -$27.5 million (Q3 2025), and -$26.2 million (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | -15.76 Mn |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | -1.51 Mn |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | -65.83 Mn |
| 10 | X4 Pharmaceuticals | 166.63 Mn | 166.63 Mn | 2.20 Mn | -23.70 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -23.70 Mn |
| Sep 30, 2025 | -27.51 Mn |
| Jun 30, 2025 | -26.23 Mn |
| Mar 31, 2025 | -9.44 Mn |
| Dec 31, 2024 | -35.72 Mn |
| Sep 30, 2024 | -34.50 Mn |
| Jun 30, 2024 | 71.10 Mn |
| Mar 31, 2024 | -37.29 Mn |
| Dec 31, 2023 | -25.20 Mn |
| Sep 30, 2023 | -27.21 Mn |
| Jun 30, 2023 | -25.81 Mn |
| Mar 31, 2023 | -29.30 Mn |
| Dec 31, 2022 | -25.58 Mn |
| Sep 30, 2022 | -20.15 Mn |
| Jun 30, 2022 | -20.57 Mn |
| Mar 31, 2022 | -21.27 Mn |
| Dec 31, 2021 | -29.06 Mn |
| Sep 30, 2021 | -19.12 Mn |
| Jun 30, 2021 | -19.00 Mn |
| Mar 31, 2021 | -17.94 Mn |