Tyra Biosciences (TYRA) Free Cash Flow (2020 - 2026)

Tyra Biosciences' (TYRA) quarterly Free Cash Flow came in at -$32.7 million in Q1 2026, down 28.29% YoY from -$45.5 million in Q1 2025, and down 37.99% on a QoQ basis from -$23.7 million in Q4 2025.

Tyra Biosciences (TYRA) Free Cash Flow (2020 - 2026) Analysis & Trends

Tyra Biosciences (TYRA) has 7 years of Free Cash Flow data on file, last reported at -$32.7 million in Q1 2026.

  • Quarterly Free Cash Flow fell 28.29% year-over-year to -$32.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$102.4 million (down 38.9% YoY) and the FY2025 annual result came in at -$95.2 million, down 35.17% from the prior year.
  • Free Cash Flow slipped to -$32.7 million in Q1 2026, from -$23.7 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of -$9.2 million in Q1 2022 to a low of -$32.7 million in Q1 2026.
  • A 5-year average of -$17.6 million and a median of -$17.3 million in 2023 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2022 — Free Cash Flow slumped 274.6% — and 2023, when it soared 43.01%.
  • Tracing TYRA's Free Cash Flow over 5 years: stood at -$12.0 million in 2022, then dropped by 18.08% to -$14.1 million in 2023, then slumped by 38.63% to -$19.6 million in 2024, then declined by 20.77% to -$23.7 million in 2025, then plunged by 37.99% to -$32.7 million in 2026.
  • The last three Free Cash Flow figures came in at -$32.7 million (Q1 2026), -$23.7 million (Q4 2025), and -$22.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Tyra Biosciences 1.51 Bn 1.51 Bn - -31.14 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -31.14 Mn
Jun 30, 2026 -31.14 Mn
Mar 31, 2026 -32.66 Mn
Mar 31, 2026 -32.66 Mn
Dec 31, 2025 -23.67 Mn
Dec 31, 2025 -23.67 Mn
Sep 30, 2025 -22.36 Mn
Sep 30, 2025 -22.36 Mn
Jun 30, 2025 -23.73 Mn
Jun 30, 2025 -23.73 Mn
Mar 31, 2025 -25.46 Mn
Mar 31, 2025 -25.46 Mn
Dec 31, 2024 -19.60 Mn
Dec 31, 2024 -19.60 Mn
Sep 30, 2024 -18.52 Mn
Sep 30, 2024 -18.52 Mn
Jun 30, 2024 -10.16 Mn
Jun 30, 2024 -10.16 Mn
Mar 31, 2024 -22.16 Mn
Mar 31, 2024 -22.16 Mn