Tyra Biosciences (TYRA) Free Cash Flow (2020 - 2026)

Tyra Biosciences (TYRA) posted Free Cash Flow of -$32.7 million for Q1 2026, down 37.99% on a QoQ basis from -$23.7 million in Q4 2025, and down 28.29% year-over-year from -$45.5 million in Q1 2025.

Tyra Biosciences (TYRA) Free Cash Flow (2020 - 2026) Analysis & Trends

Tyra Biosciences' Free Cash Flow history runs 7 years deep, the most recent figure standing at -$32.7 million for Q1 2026.

  • Quarterly Free Cash Flow fell 28.29% year-over-year to -$32.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$102.4 million (down 38.9% YoY) and the FY2025 annual result came in at -$95.2 million, down 35.17% from the prior year.
  • Free Cash Flow was -$32.7 million for Q1 2026 at Tyra Biosciences, down from -$23.7 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$9.2 million in Q1 2022 and bottomed at -$32.7 million in Q1 2026.
  • A 5-year average of -$17.6 million and a median of -$17.3 million in 2023 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2022 — Free Cash Flow sank 274.6% — and 2023, when it soared 43.01%.
  • Tyra Biosciences' Free Cash Flow stood at -$12.0 million in 2022, then fell by 18.08% to -$14.1 million in 2023, then plunged by 38.63% to -$19.6 million in 2024, then retreated by 20.77% to -$23.7 million in 2025, then slumped by 37.99% to -$32.7 million in 2026.
  • Business Quant data shows TYRA's Free Cash Flow at -$32.7 million in Q1 2026, -$23.7 million in Q4 2025, and -$22.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Tyra Biosciences 1.90 Bn 1.90 Bn - -32.66 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -32.66 Mn
Mar 31, 2026 -32.66 Mn
Dec 31, 2025 -23.67 Mn
Dec 31, 2025 -23.67 Mn
Sep 30, 2025 -22.36 Mn
Sep 30, 2025 -22.36 Mn
Jun 30, 2025 -23.73 Mn
Jun 30, 2025 -23.73 Mn
Mar 31, 2025 -25.46 Mn
Mar 31, 2025 -25.46 Mn
Dec 31, 2024 -19.60 Mn
Dec 31, 2024 -19.60 Mn
Sep 30, 2024 -18.52 Mn
Sep 30, 2024 -18.52 Mn
Jun 30, 2024 -10.16 Mn
Jun 30, 2024 -10.16 Mn
Mar 31, 2024 -22.16 Mn
Mar 31, 2024 -22.16 Mn
Dec 31, 2023 -14.14 Mn
Dec 31, 2023 -14.14 Mn