Tyra Biosciences (TYRA) Free Cash Flow (2020 - 2026)

Quarterly Free Cash Flow fell 27.95% to -$32.6 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was -$102.3 million through Mar 2026, down 40.02% year-over-year, with the annual reading at -$95.2 million for FY2025, 36.45% down from the prior year.

Tyra Biosciences filings provide 7 years of Free Cash Flow readings, the most recent being -$32.6 million for Q1 2026.

  • Free Cash Flow hit -$32.6 million in Q1 2026 for Tyra Biosciences, down from -$23.7 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$9.2 million in Q1 2022 and bottomed at -$32.6 million in Q1 2026.
  • Average Free Cash Flow over 5 years is -$17.5 million, with a median of -$17.2 million recorded in 2023.
  • The largest annual shift saw Free Cash Flow plummeted 274.6% in 2022 before it skyrocketed 43.05% in 2023.
  • Tyra Biosciences' Free Cash Flow stood at -$12.0 million in 2022, then decreased by 12.69% to -$13.5 million in 2023, then plummeted by 40.34% to -$18.9 million in 2024, then fell by 25.01% to -$23.7 million in 2025, then plummeted by 37.71% to -$32.6 million in 2026.
  • Per Business Quant, the three most recent readings for TYRA's Free Cash Flow are -$32.6 million (Q1 2026), -$23.7 million (Q4 2025), and -$22.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -1.67 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.29 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 848.30 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 48.67 Mn
10 Tyra Biosciences 2.03 Bn 2.03 Bn - -32.59 Mn

Historic Data

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DateValue
Mar 31, 2026 -32.59 Mn
Mar 31, 2026 -32.59 Mn
Dec 31, 2025 -23.67 Mn
Dec 31, 2025 -23.67 Mn
Sep 30, 2025 -22.36 Mn
Sep 30, 2025 -22.36 Mn
Jun 30, 2025 -23.71 Mn
Jun 30, 2025 -23.71 Mn
Mar 31, 2025 -25.47 Mn
Mar 31, 2025 -25.47 Mn
Dec 31, 2024 -18.93 Mn
Dec 31, 2024 -18.93 Mn
Sep 30, 2024 -17.95 Mn
Sep 30, 2024 -17.95 Mn
Jun 30, 2024 -10.73 Mn
Jun 30, 2024 -10.73 Mn
Mar 31, 2024 -22.16 Mn
Mar 31, 2024 -22.16 Mn
Dec 31, 2023 -13.49 Mn
Dec 31, 2023 -13.49 Mn
Sep 30, 2023 -17.23 Mn
Sep 30, 2023 -17.23 Mn
Jun 30, 2023 -9.66 Mn
Jun 30, 2023 -9.66 Mn
Mar 31, 2023 -9.89 Mn
Mar 31, 2023 -9.89 Mn
Dec 31, 2022 -11.97 Mn
Dec 31, 2022 -11.97 Mn
Sep 30, 2022 -12.19 Mn
Sep 30, 2022 -12.19 Mn
Jun 30, 2022 -16.96 Mn
Jun 30, 2022 -16.96 Mn
Mar 31, 2022 -9.16 Mn
Mar 31, 2022 -9.16 Mn
Dec 31, 2021 -9.67 Mn
Dec 31, 2021 -9.67 Mn
Sep 30, 2021 -5.47 Mn
Sep 30, 2021 -5.47 Mn
Jun 30, 2021 -4.53 Mn
Jun 30, 2021 -4.53 Mn
Mar 31, 2021 -4.74 Mn
Mar 31, 2021 -4.74 Mn
Dec 31, 2020 -2.29 Mn
Dec 31, 2020 -2.29 Mn