Tyra Biosciences (TYRA) Enterprise Value (2020 - 2026)

Tyra Biosciences (TYRA) posted Enterprise Value of -$85.0 million for Q1 2026, down 9.78% on a QoQ basis from -$77.4 million in Q4 2025, and up 15.65% year-over-year from -$73.5 million in Q1 2025.

Tyra Biosciences (TYRA) Enterprise Value (2020 - 2026) Analysis & Trends

Tyra Biosciences' Enterprise Value history runs 7 years deep, the most recent figure standing at -$85.0 million for Q1 2026.

  • Quarterly Enterprise Value rose 15.65% year-over-year to -$85.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$85.0 million (up 15.65% YoY) and the FY2025 annual result came in at -$77.4 million, up 15.85% from the prior year.
  • Enterprise Value was -$85.0 million for Q1 2026 at Tyra Biosciences, down from -$77.4 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$58.0 million in Q4 2023 and bottomed at -$292.5 million in Q1 2022.
  • A 5-year average of -$164.9 million and a median of -$103.9 million in 2024 frame the typical range for Enterprise Value.
  • Annual changes were most pronounced in 2022 — Enterprise Value sank 107.98% — and 2023, when it surged 76.91%.
  • Tyra Biosciences' Enterprise Value stood at -$251.2 million in 2022, then jumped by 76.91% to -$58.0 million in 2023, then sank by 58.55% to -$92.0 million in 2024, then gained by 15.85% to -$77.4 million in 2025, then retreated by 9.78% to -$85.0 million in 2026.
  • Business Quant data shows TYRA's Enterprise Value at -$85.0 million in Q1 2026, -$77.4 million in Q4 2025, and -$62.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Tyra Biosciences 1.90 Bn 1.90 Bn - -84.96 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -84.96 Mn
Dec 31, 2025 -77.39 Mn
Sep 30, 2025 -61.95 Mn
Jun 30, 2025 -98.49 Mn
Mar 31, 2025 -100.72 Mn
Dec 31, 2024 -91.97 Mn
Sep 30, 2024 -103.89 Mn
Jun 30, 2024 -99.49 Mn
Mar 31, 2024 -254.37 Mn
Dec 31, 2023 -58.01 Mn
Sep 30, 2023 -215.65 Mn
Jun 30, 2023 -232.41 Mn
Mar 31, 2023 -241.70 Mn
Dec 31, 2022 -251.21 Mn
Sep 30, 2022 -263.21 Mn
Jun 30, 2022 -275.11 Mn
Mar 31, 2022 -292.50 Mn
Dec 31, 2021 -302.18 Mn
Sep 30, 2021 -312.82 Mn
Jun 30, 2021 -135.20 Mn