10x Genomics (TXG) Operating Margin (2018 - 2026)

10x Genomics (TXG) reported Operating Margin of 11.3% for Q1 2026, up 1409.0% on a YoY basis from 0.75% in Q1 2025, and up 3.99% sequentially from 11.77% in Q4 2025.

10x Genomics (TXG) Operating Margin (2018 - 2026) Analysis & Trends

10x Genomics (TXG) has 9 years of Operating Margin data on file, last reported at 11.3% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin rose 1409.0% year-over-year to 11.3%; the trailing twelve-month figure through Mar 2026 stood at 6.06% (up 2154.0% YoY), and the FY2025 full-year result was 9.49%, up 2237.0% from the prior year.
  • Operating Margin advanced to 11.3% in Q1 2026, from 11.77% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 17.42% in Q2 2025 to a low of 61.7% in Q3 2023.
  • A 5-year average of 28.91% and a median of 30.0% in 2023 frame the typical range for Operating Margin.
  • Across the five-year window, Operating Margin slumped 4616 bps in 2022 and soared 4468 bps in 2025, its largest moves.
  • Tracing TXG's Operating Margin over 5 years: stood at 14.78% in 2022, then tumbled by 103 bps to 30.0% in 2023, then decreased by 1 bps to 30.2% in 2024, then surged by 61 bps to 11.77% in 2025, then advanced by 4 bps to 11.3% in 2026.
  • Business Quant data shows TXG's Operating Margin at 11.3% in Q1 2026, 11.77% in Q4 2025, and 21.64% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Veeva Systems 29.34 Bn 22.03 Bn 662.02 Mn 30.93%
2 BrightSpring Health Services 13.49 Bn 12.59 Bn 482.22 Mn 3.36%
3 Healthequity 7.96 Bn 7.70 Bn 256.31 Mn 29.03%
4 10x Genomics 6.17 Bn 5.63 Bn 106.18 Mn -11.30%
5 Hinge Health 6.02 Bn 5.70 Bn 154.23 Mn 17.59%
6 MiniMed 4.19 Bn 3.89 Bn 480.00 Mn -11.11%
7 Waystar Holding 4.14 Bn 4.07 Bn 216.84 Mn 25.64%
8 Doximity 3.82 Bn 3.08 Bn 125.97 Mn 17.08%
9 Privia Health 3.10 Bn 2.73 Bn - 1.23%
10 Omnicell 1.81 Bn 1.57 Bn 140.36 Mn 5.44%

Historic Data

Download Data
DateValue
Mar 31, 2026 -11.30%
Dec 31, 2025 -11.77%
Sep 30, 2025 -21.64%
Jun 30, 2025 17.42%
Mar 31, 2025 -25.39%
Dec 31, 2024 -30.20%
Sep 30, 2024 -27.36%
Jun 30, 2024 -27.26%
Mar 31, 2024 -43.61%
Dec 31, 2023 -30.00%
Sep 30, 2023 -61.70%
Jun 30, 2023 -43.15%
Mar 31, 2023 -38.71%
Dec 31, 2022 -14.78%
Sep 30, 2022 -30.51%
Jun 30, 2022 -55.07%
Mar 31, 2022 -36.45%
Dec 31, 2021 -11.03%
Sep 30, 2021 -12.67%
Jun 30, 2021 -8.92%