10x Genomics (TXG) Operating Margin (2018 - 2026)
10x Genomics (TXG) reported Operating Margin of -12.95% for Q2 2026, down 30.37 percentage points from 17.42% a year earlier and down 1.65 percentage points from the prior quarter.
Powered by 
Analysis
10x Genomics (TXG) Operating Margin (2018 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, 10x Genomics' Operating Margin came in at -14.33%, up 1.27 percentage points year-over-year; for FY2025, it came in at -9.49%, up 22.37 percentage points from FY2024.
- Operating Margin has a five-year change of +169.25 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -31.85% in FY2024 (+11.03 pp), -42.88% in FY2023 (-10.36 pp), -32.52% in FY2022 (-21.87 pp) and -10.65% in FY2021 (+168.08 pp).
- Five-year quarterly Operating Margin spans a low of -61.70% in Q3 2023 and a high of 17.42% in Q2 2025.
- Year over year, Operating Margin gained in six of the last eight quarters, with an average year-over-year change of +13.11 percentage points.
- The high point for year-over-year Operating Margin in five years was Q4 2021 (a gain of 353.96 percentage points); the low point was Q2 2022 (a drop of 46.16 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -11.30% (Q1 2026), -11.77% (Q4 2025) and -21.64% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 251.93 Bn | 230.96 Bn | 4.88 Bn | 17.40% |
| 2 | Abbott Laboratories | 181.29 Bn | 151.72 Bn | 7.27 Bn | 13.44% |
| 3 | Danaher | 158.18 Bn | 141.99 Bn | 3.61 Bn | 17.99% |
| 4 | Intuitive Surgical | 153.47 Bn | 132.89 Bn | 1.96 Bn | 33.60% |
| 5 | Medtronic | 118.97 Bn | 84.22 Bn | 6.34 Bn | 18.08% |
| 6 | Stryker | 114.72 Bn | 100.84 Bn | 4.50 Bn | 25.18% |
| 7 | Boston Scientific | 66.18 Bn | 60.95 Bn | 3.85 Bn | 21.65% |
| 8 | Becton Dickinson | 52.49 Bn | 49.64 Bn | 2.32 Bn | 13.31% |
| 9 | Edwards Lifesciences | 50.32 Bn | 34.33 Bn | 1.35 Bn | 29.48% |
| 10 | 10x Genomics | 9.07 Bn | 8.87 Bn | 112.50 Mn | -12.95% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -12.95% |
| Mar 31, 2026 | -11.30% |
| Dec 31, 2025 | -11.77% |
| Sep 30, 2025 | -21.64% |
| Jun 30, 2025 | 17.42% |
| Mar 31, 2025 | -25.39% |
| Dec 31, 2024 | -30.20% |
| Sep 30, 2024 | -27.36% |
| Jun 30, 2024 | -27.26% |
| Mar 31, 2024 | -43.61% |
| Dec 31, 2023 | -30.00% |
| Sep 30, 2023 | -61.70% |
| Jun 30, 2023 | -43.15% |
| Mar 31, 2023 | -38.71% |
| Dec 31, 2022 | -14.78% |
| Sep 30, 2022 | -30.51% |
| Jun 30, 2022 | -55.07% |
| Mar 31, 2022 | -36.45% |
| Dec 31, 2021 | -11.03% |
| Sep 30, 2021 | -12.67% |
API Access
10x Genomics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=TXG&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "TXG", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=TXG&period=max&api_key=YOUR_API_KEY");
const data = await res.json();