10x Genomics (TXG) Operating Margin (2018 - 2026)

10x Genomics (TXG) posted Operating Margin of 11.3% for Q1 2026, up 3.99% sequentially from 11.77% in Q4 2025, and up 1409.0% YoY from 0.75% in Q1 2025.

10x Genomics (TXG) Operating Margin (2018 - 2026) Analysis & Trends

10x Genomics has reported Operating Margin for 9 years, with the latest figure at 11.3% in Q1 2026.

  • Quarterly Operating Margin rose 1409.0% year-over-year to 11.3% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 6.06% (up 2154.0% YoY) and the FY2025 annual result came in at 9.49%, up 2237.0% from the prior year.
  • Operating Margin advanced to 11.3% in Q1 2026 per TXG's latest filing, from 11.77% in the prior quarter.
  • Over five years, Operating Margin peaked at 17.42% in Q2 2025 and troughed at 61.7% in Q3 2023.
  • A 5-year average of 28.91% and a median of 30.0% in 2023 frame the typical range for Operating Margin.
  • The sharpest annual moves came in 2022 and 2025: Operating Margin plunged 4616 bps in 2022, then surged 4468 bps in 2025.
  • Over 5 years, Operating Margin stood at 14.78% in 2022, then slumped by 103 bps to 30.0% in 2023, then declined by 1 bps to 30.2% in 2024, then surged by 61 bps to 11.77% in 2025, then increased by 4 bps to 11.3% in 2026.
  • According to Business Quant data, Operating Margin over the past three periods registered 11.3%, 11.77%, and 21.64% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Veeva Systems 39.72 Bn 32.40 Bn 662.02 Mn 30.93%
2 BrightSpring Health Services 12.19 Bn 11.64 Bn 492.75 Mn 3.37%
3 Healthequity 8.79 Bn 8.52 Bn 256.31 Mn 29.03%
4 10x Genomics 7.31 Bn 6.76 Bn 112.50 Mn -12.95%
5 Hinge Health 7.10 Bn 6.71 Bn 183.95 Mn 19.00%
6 MiniMed 5.66 Bn 5.36 Bn 480.00 Mn -11.11%
7 Waystar Holding 4.76 Bn 4.56 Bn 221.99 Mn 23.79%
8 Doximity 4.46 Bn 3.77 Bn 132.93 Mn 21.48%
9 Heartflow 3.66 Bn 3.28 Bn 53.19 Mn -27.93%
10 Privia Health 2.78 Bn 2.42 Bn - 1.86%

Historic Data

Download Data
DateValue
Jun 30, 2026 -12.95%
Mar 31, 2026 -11.30%
Dec 31, 2025 -11.77%
Sep 30, 2025 -21.64%
Jun 30, 2025 17.42%
Mar 31, 2025 -25.39%
Dec 31, 2024 -30.20%
Sep 30, 2024 -27.36%
Jun 30, 2024 -27.26%
Mar 31, 2024 -43.61%
Dec 31, 2023 -30.00%
Sep 30, 2023 -61.70%
Jun 30, 2023 -43.15%
Mar 31, 2023 -38.71%
Dec 31, 2022 -14.78%
Sep 30, 2022 -30.51%
Jun 30, 2022 -55.07%
Mar 31, 2022 -36.45%
Dec 31, 2021 -11.03%
Sep 30, 2021 -12.67%