10x Genomics (TXG) Operating Margin (2018 - 2026)

10x Genomics' (TXG) quarterly Operating Margin came in at 11.3% in Q1 2026, up 1409.0% year-on-year from 0.75% in Q1 2025, and up 3.99% quarter-over-quarter from 11.77% in Q4 2025.

10x Genomics (TXG) Operating Margin (2018 - 2026) Analysis & Trends

10x Genomics has disclosed Operating Margin across 9 years of filings, most recently posting 11.3% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 11.3%, up 1409.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 6.06% (up 2154.0% YoY), and the FY2025 annual result was 9.49%, up 2237.0% from the prior year.
  • Operating Margin came in at 11.3% for Q1 2026 at 10x Genomics, up from 11.77% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 17.42% in Q2 2025 to a low of 61.7% in Q3 2023.
  • The 5-year median for Operating Margin is 30.0% (2023), against an average of 28.91%.
  • Across the five-year window, Operating Margin plunged 4616 bps in 2022 and soared 4468 bps in 2025, its largest moves.
  • 10x Genomics' Operating Margin stood at 14.78% in 2022, then slumped by 103 bps to 30.0% in 2023, then slipped by 1 bps to 30.2% in 2024, then soared by 61 bps to 11.77% in 2025, then climbed by 4 bps to 11.3% in 2026.
  • The last three Operating Margin figures came in at 11.3% (Q1 2026), 11.77% (Q4 2025), and 21.64% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 30.93%
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 3.36%
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 29.03%
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 17.59%
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn -11.30%
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 17.08%
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 25.64%
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 1.23%
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 5.44%
10 Teladoc Health 1.45 Bn 696.57 Mn 562.57 Mn -10.06%

Historic Data

Download Data
DateValue
Mar 31, 2026 -11.30%
Dec 31, 2025 -11.77%
Sep 30, 2025 -21.64%
Jun 30, 2025 17.42%
Mar 31, 2025 -25.39%
Dec 31, 2024 -30.20%
Sep 30, 2024 -27.36%
Jun 30, 2024 -27.26%
Mar 31, 2024 -43.61%
Dec 31, 2023 -30.00%
Sep 30, 2023 -61.70%
Jun 30, 2023 -43.15%
Mar 31, 2023 -38.71%
Dec 31, 2022 -14.78%
Sep 30, 2022 -30.51%
Jun 30, 2022 -55.07%
Mar 31, 2022 -36.45%
Dec 31, 2021 -11.03%
Sep 30, 2021 -12.67%
Jun 30, 2021 -8.92%