Entrada Therapeutics (TRDA) Operating Income (2020 - 2026)

Entrada Therapeutics' (TRDA) quarterly Operating Income came in at -$42.3 million in Q1 2026, down 94.14% year-on-year from -$721.8 million in Q1 2025, and little changed quarter-over-quarter from -$42.2 million in Q4 2025.

Entrada Therapeutics (TRDA) Operating Income (2020 - 2026) Analysis & Trends

Entrada Therapeutics' Operating Income history runs 7 years deep, the most recent figure standing at -$42.3 million for Q1 2026.

  • On a quarterly basis, Operating Income fell 94.14% year-over-year to -$42.3 million in Q1 2026; TTM through Mar 2026 was -$178.4 million, a 4443.01% decrease from a year earlier, with the FY2025 full-year figure at -$157.9 million, down 435.87% from the prior year.
  • Operating Income held at -$42.3 million in Q1 2026 per TRDA's latest filing, from -$42.2 million in the prior quarter.
  • Across five years, Operating Income topped out at $53.4 million in Q2 2024 and bottomed at -$47.1 million in Q3 2025.
  • The 5-year median for Operating Income is -$21.8 million (2025), against an average of -$14.9 million.
  • Across the five-year window, Operating Income jumped 465.28% in 2024 and sank 619.41% in 2025, its largest moves.
  • Year by year, Operating Income stood at -$25.6 million in 2022, then surged by 119.18% to $4.9 million in 2023, then slumped by 219.61% to -$5.9 million in 2024, then sank by 619.41% to -$42.2 million in 2025, then fell by 0.23% to -$42.3 million in 2026.
  • Per Business Quant, the three latest TRDA Operating Income figures stand at -$42.3 million (Q1 2026), -$42.2 million (Q4 2025), and -$47.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Entrada Therapeutics 245.16 Mn 245.16 Mn - -42.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -42.30 Mn
Dec 31, 2025 -42.21 Mn
Sep 30, 2025 -47.05 Mn
Jun 30, 2025 -46.85 Mn
Mar 31, 2025 -21.79 Mn
Dec 31, 2024 -5.87 Mn
Sep 30, 2024 -21.66 Mn
Jun 30, 2024 53.42 Mn
Mar 31, 2024 21.11 Mn
Dec 31, 2023 4.91 Mn
Sep 30, 2023 14.01 Mn
Jun 30, 2023 -16.30 Mn
Mar 31, 2023 -5.78 Mn
Dec 31, 2022 -25.58 Mn
Sep 30, 2022 -25.94 Mn
Jun 30, 2022 -23.58 Mn
Mar 31, 2022 -22.15 Mn
Dec 31, 2021 -18.46 Mn
Sep 30, 2021 -14.36 Mn
Jun 30, 2021 -9.91 Mn