Synlogic (SYBX) EBITDA (2016 - 2025)
Synlogic (SYBX) recorded EBITDA of -$1.34 million in Q4 2025, compared with -$1.78 million a year earlier.
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Analysis
Synlogic (SYBX) EBITDA (2016 - 2025) Analysis & Trends
For FY2025, Synlogic reported EBITDA of -$4.01 million.
- Across earlier years, EBITDA came in at -$40.6 million in FY2024, -$53.16 million in FY2023, -$64.9 million in FY2022 and -$58.32 million in FY2021.
- Quarterly EBITDA has ranged from -$38.5 million in Q1 2024 to $419,000 in Q2 2024 over the past five years.
- Per Business Quant, the preceding three quarters came in at -$991,000 (Q3 2025), -$777,000 (Q2 2025) and -$898,000 (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,165.22 Bn | 1,133.81 Bn | 19.71 Bn | 12.29 Bn |
| 2 | Johnson & Johnson | 646.28 Bn | 566.14 Bn | 17.30 Bn | 8.30 Bn |
| 3 | AbbVie | 503.17 Bn | 476.28 Bn | 12.70 Bn | 8.33 Bn |
| 4 | Merck | 365.23 Bn | 319.60 Bn | 12.21 Bn | 999.00 Mn |
| 5 | Novartis Ag | 302.66 Bn | 266.65 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 267.39 Bn | 241.08 Bn | 12.86 Bn | 5.09 Bn |
| 7 | Amgen | 241.61 Bn | 197.01 Bn | 7.24 Bn | 4.63 Bn |
| 8 | Gilead Sciences | 194.67 Bn | 168.86 Bn | 6.22 Bn | -9.70 Bn |
| 9 | Pfizer | 172.91 Bn | 119.55 Bn | 10.94 Bn | 5.89 Bn |
| 10 | Synlogic | 12.42 Mn | -48.05 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -1.34 Mn |
| Sep 30, 2025 | -991,000.00 |
| Jun 30, 2025 | -777,000.00 |
| Mar 31, 2025 | -898,000.00 |
| Dec 31, 2024 | -1.78 Mn |
| Sep 30, 2024 | -748,000.00 |
| Jun 30, 2024 | 419,000.00 |
| Mar 31, 2024 | -38.50 Mn |
| Dec 31, 2023 | -10.20 Mn |
| Sep 30, 2023 | -12.17 Mn |
| Jun 30, 2023 | -15.12 Mn |
| Mar 31, 2023 | -15.67 Mn |
| Dec 31, 2022 | -16.69 Mn |
| Sep 30, 2022 | -17.68 Mn |
| Jun 30, 2022 | -15.36 Mn |
| Mar 31, 2022 | -15.16 Mn |
| Dec 31, 2021 | -14.53 Mn |
| Sep 30, 2021 | -15.46 Mn |
| Jun 30, 2021 | -13.93 Mn |
| Mar 31, 2021 | -14.41 Mn |
API Access
Synlogic EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=SYBX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "SYBX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=SYBX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();