Sutro Biopharma (STRO) Operating Income (2017 - 2025)

Sutro Biopharma's (STRO) quarterly Operating Income came in at -$38.0 million in Q4 2025, up 41.69% year-on-year from -$26.9 million in Q4 2024, and up 21.48% quarter-over-quarter from -$48.5 million in Q3 2025.

Sutro Biopharma (STRO) Operating Income (2017 - 2025) Analysis & Trends

Sutro Biopharma has disclosed Operating Income across 9 years of filings, most recently posting -$38.0 million for Q4 2025.

  • Operating Income for Q4 2025 came in at -$38.0 million, up 41.69% year-over-year; the trailing twelve-month figure through Dec 2025 was -$158.4 million (up 33.59% YoY), and the FY2025 annual result was -$158.4 million, up 33.59% from the prior year.
  • Operating Income came in at -$38.0 million for Q4 2025 at Sutro Biopharma, up from -$48.5 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $43.2 million in Q4 2023 to a low of -$68.5 million in Q1 2025.
  • The 5-year median for Operating Income is -$40.7 million (2022), against an average of -$35.7 million.
  • Across the five-year window, Operating Income soared 187.67% in 2023 and sank 251.23% in 2024, its largest moves.
  • Sutro Biopharma's Operating Income stood at -$35.0 million in 2021, then tumbled by 40.49% to -$49.2 million in 2022, then jumped by 187.67% to $43.2 million in 2023, then tumbled by 251.23% to -$65.3 million in 2024, then soared by 41.69% to -$38.0 million in 2025.
  • The last three Operating Income figures came in at -$38.0 million (Q4 2025), -$48.5 million (Q3 2025), and -$3.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Sutro Biopharma 252.04 Mn 252.04 Mn - -38.05 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -38.05 Mn
Sep 30, 2025 -48.46 Mn
Jun 30, 2025 -3.35 Mn
Mar 31, 2025 -68.51 Mn
Dec 31, 2024 -65.26 Mn
Sep 30, 2024 -67.92 Mn
Jun 30, 2024 -48.69 Mn
Mar 31, 2024 -56.59 Mn
Dec 31, 2023 43.15 Mn
Sep 30, 2023 -44.01 Mn
Jun 30, 2023 -46.18 Mn
Mar 31, 2023 -42.24 Mn
Dec 31, 2022 -49.22 Mn
Sep 30, 2022 -21.21 Mn
Jun 30, 2022 -19.38 Mn
Mar 31, 2022 -39.13 Mn
Dec 31, 2021 -35.04 Mn
Sep 30, 2021 -34.67 Mn
Jun 30, 2021 -9.81 Mn
Mar 31, 2021 -19.01 Mn