Sutro Biopharma (STRO) Operating Income (2017 - 2025)
Sutro Biopharma (STRO) reported Operating Income of -$38.0 million for Q4 2025, up 41.69% on a YoY basis from -$26.9 million in Q4 2024, and up 21.48% sequentially from -$48.5 million in Q3 2025.
Sutro Biopharma (STRO) Operating Income (2017 - 2025) Analysis & Trends
Sutro Biopharma (STRO) has 9 years of Operating Income data on file, last reported at -$38.0 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Income rose 41.69% year-over-year to -$38.0 million; the trailing twelve-month figure through Dec 2025 stood at -$158.4 million (up 33.59% YoY), and the FY2025 full-year result was -$158.4 million, up 33.59% from the prior year.
- Operating Income advanced to -$38.0 million in Q4 2025, from -$48.5 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $43.2 million in Q4 2023 to a low of -$68.5 million in Q1 2025.
- A 5-year average of -$35.7 million and a median of -$40.7 million in 2022 frame the typical range for Operating Income.
- Across the five-year window, Operating Income soared 187.67% in 2023 and tumbled 251.23% in 2024, its largest moves.
- Tracing STRO's Operating Income over 5 years: stood at -$35.0 million in 2021, then plunged by 40.49% to -$49.2 million in 2022, then soared by 187.67% to $43.2 million in 2023, then plunged by 251.23% to -$65.3 million in 2024, then surged by 41.69% to -$38.0 million in 2025.
- Business Quant data shows STRO's Operating Income at -$38.0 million in Q4 2025, -$48.5 million in Q3 2025, and -$3.3 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Sutro Biopharma | 192.86 Mn | 51.43 Mn | - | -38.05 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -38.05 Mn |
| Sep 30, 2025 | -48.46 Mn |
| Jun 30, 2025 | -3.35 Mn |
| Mar 31, 2025 | -68.51 Mn |
| Dec 31, 2024 | -65.26 Mn |
| Sep 30, 2024 | -67.92 Mn |
| Jun 30, 2024 | -48.69 Mn |
| Mar 31, 2024 | -56.59 Mn |
| Dec 31, 2023 | 43.15 Mn |
| Sep 30, 2023 | -44.01 Mn |
| Jun 30, 2023 | -46.18 Mn |
| Mar 31, 2023 | -42.24 Mn |
| Dec 31, 2022 | -49.22 Mn |
| Sep 30, 2022 | -21.21 Mn |
| Jun 30, 2022 | -19.38 Mn |
| Mar 31, 2022 | -39.13 Mn |
| Dec 31, 2021 | -35.04 Mn |
| Sep 30, 2021 | -34.67 Mn |
| Jun 30, 2021 | -9.81 Mn |
| Mar 31, 2021 | -19.01 Mn |