Sutro Biopharma (STRO) EBITDA (2017 - 2025)
Sutro Biopharma recorded quarterly EBITDA of -$38.0 million in Q4 2025, up 21.48% quarter-over-quarter from -$48.5 million in Q3 2025, and up 41.69% year-over-year from -$26.9 million in Q4 2024.
Sutro Biopharma's EBITDA history runs 9 years deep, the most recent figure standing at -$38.0 million for Q4 2025.
- In Q4 2025, EBITDA rose 41.69% year-over-year to -$38.0 million; the TTM figure through Dec 2025 stood at -$158.4 million (up 33.59% YoY), while the FY2025 annual figure was -$158.4 million, up 33.59% from the prior year.
- EBITDA came in at -$38.0 million for Q4 2025 at Sutro Biopharma, up from -$48.5 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of $43.2 million in Q4 2023 to a low of -$68.5 million in Q1 2025.
- A 5-year average of -$35.7 million and a median of -$40.7 million in 2022 frame the typical range for EBITDA.
- Across the five-year window, EBITDA jumped 187.67% in 2023 and plunged 251.23% in 2024, its largest moves.
- Sutro Biopharma's EBITDA stood at -$35.0 million in 2021, then slumped by 40.49% to -$49.2 million in 2022, then surged by 187.67% to $43.2 million in 2023, then slumped by 251.23% to -$65.3 million in 2024, then jumped by 41.69% to -$38.0 million in 2025.
- According to Business Quant data, EBITDA over the past three periods registered -$38.0 million, -$48.5 million, and -$3.3 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 661.60 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Sutro Biopharma | 242.87 Mn | 242.87 Mn | - | -38.05 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -38.05 Mn |
| Sep 30, 2025 | -48.46 Mn |
| Jun 30, 2025 | -3.35 Mn |
| Mar 31, 2025 | -68.51 Mn |
| Dec 31, 2024 | -65.26 Mn |
| Sep 30, 2024 | -67.92 Mn |
| Jun 30, 2024 | -48.69 Mn |
| Mar 31, 2024 | -56.59 Mn |
| Dec 31, 2023 | 43.15 Mn |
| Sep 30, 2023 | -44.01 Mn |
| Jun 30, 2023 | -46.18 Mn |
| Mar 31, 2023 | -42.24 Mn |
| Dec 31, 2022 | -49.22 Mn |
| Sep 30, 2022 | -21.21 Mn |
| Jun 30, 2022 | -19.38 Mn |
| Mar 31, 2022 | -39.13 Mn |
| Dec 31, 2021 | -35.04 Mn |
| Sep 30, 2021 | -34.67 Mn |
| Jun 30, 2021 | -9.81 Mn |
| Mar 31, 2021 | -19.01 Mn |
| Dec 31, 2020 | -24.84 Mn |
| Sep 30, 2020 | -10.62 Mn |
| Jun 30, 2020 | -16.42 Mn |
| Mar 31, 2020 | -19.18 Mn |
| Dec 31, 2019 | -14.78 Mn |
| Sep 30, 2019 | -12.74 Mn |
| Jun 30, 2019 | -13.69 Mn |
| Mar 31, 2019 | -14.27 Mn |
| Dec 31, 2018 | -3.28 Mn |
| Sep 30, 2018 | -10.16 Mn |
| Jun 30, 2018 | -12.09 Mn |
| Mar 31, 2018 | -11.70 Mn |
| Dec 31, 2017 | -15.17 Mn |
| Sep 30, 2017 | -1.07 Mn |