Sutro Biopharma (STRO) EBITDA (2017 - 2025)

Sutro Biopharma recorded quarterly EBITDA of -$38.0 million in Q4 2025, up 21.48% quarter-over-quarter from -$48.5 million in Q3 2025, and up 41.69% year-over-year from -$26.9 million in Q4 2024.

Sutro Biopharma's EBITDA history runs 9 years deep, the most recent figure standing at -$38.0 million for Q4 2025.

  • In Q4 2025, EBITDA rose 41.69% year-over-year to -$38.0 million; the TTM figure through Dec 2025 stood at -$158.4 million (up 33.59% YoY), while the FY2025 annual figure was -$158.4 million, up 33.59% from the prior year.
  • EBITDA came in at -$38.0 million for Q4 2025 at Sutro Biopharma, up from -$48.5 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $43.2 million in Q4 2023 to a low of -$68.5 million in Q1 2025.
  • A 5-year average of -$35.7 million and a median of -$40.7 million in 2022 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA jumped 187.67% in 2023 and plunged 251.23% in 2024, its largest moves.
  • Sutro Biopharma's EBITDA stood at -$35.0 million in 2021, then slumped by 40.49% to -$49.2 million in 2022, then surged by 187.67% to $43.2 million in 2023, then slumped by 251.23% to -$65.3 million in 2024, then jumped by 41.69% to -$38.0 million in 2025.
  • According to Business Quant data, EBITDA over the past three periods registered -$38.0 million, -$48.5 million, and -$3.3 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Sutro Biopharma 242.87 Mn 242.87 Mn - -38.05 Mn

Historic Data

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DateValue
Dec 31, 2025 -38.05 Mn
Sep 30, 2025 -48.46 Mn
Jun 30, 2025 -3.35 Mn
Mar 31, 2025 -68.51 Mn
Dec 31, 2024 -65.26 Mn
Sep 30, 2024 -67.92 Mn
Jun 30, 2024 -48.69 Mn
Mar 31, 2024 -56.59 Mn
Dec 31, 2023 43.15 Mn
Sep 30, 2023 -44.01 Mn
Jun 30, 2023 -46.18 Mn
Mar 31, 2023 -42.24 Mn
Dec 31, 2022 -49.22 Mn
Sep 30, 2022 -21.21 Mn
Jun 30, 2022 -19.38 Mn
Mar 31, 2022 -39.13 Mn
Dec 31, 2021 -35.04 Mn
Sep 30, 2021 -34.67 Mn
Jun 30, 2021 -9.81 Mn
Mar 31, 2021 -19.01 Mn
Dec 31, 2020 -24.84 Mn
Sep 30, 2020 -10.62 Mn
Jun 30, 2020 -16.42 Mn
Mar 31, 2020 -19.18 Mn
Dec 31, 2019 -14.78 Mn
Sep 30, 2019 -12.74 Mn
Jun 30, 2019 -13.69 Mn
Mar 31, 2019 -14.27 Mn
Dec 31, 2018 -3.28 Mn
Sep 30, 2018 -10.16 Mn
Jun 30, 2018 -12.09 Mn
Mar 31, 2018 -11.70 Mn
Dec 31, 2017 -15.17 Mn
Sep 30, 2017 -1.07 Mn