Sarepta Therapeutics (SRPT) EBITDA (2010 - 2026)

Sarepta Therapeutics (SRPT) recorded quarterly EBITDA of $358.4 million in Q1 2026, up 187.09% quarter-over-quarter from -$411.6 million in Q4 2025, and up 219.32% on a YoY basis from $112.2 million in Q1 2025.

Sarepta Therapeutics (SRPT) EBITDA (2010 - 2026) Analysis & Trends

Sarepta Therapeutics' EBITDA history runs 17 years deep, the most recent figure standing at $358.4 million for Q1 2026.

  • In Q1 2026, EBITDA rose 219.32% year-over-year to $358.4 million; the TTM figure through Mar 2026 stood at -$36.0 million (up 62.36% YoY), while the FY2025 annual figure was -$699.8 million, down 420.88% from the prior year.
  • EBITDA was $358.4 million for Q1 2026 at Sarepta Therapeutics, up from -$411.6 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $358.4 million in Q1 2026 to a low of -$515.5 million in Q1 2023.
  • Historically, EBITDA has averaged -$78.6 million across 5 years, with a median of -$40.5 million in 2023.
  • Biggest YoY gain for EBITDA was 3115.28% in 2025; the steepest drop was 970.43% in 2025.
  • A 5-year view of EBITDA shows it stood at -$107.7 million in 2022, then jumped by 143.83% to $47.2 million in 2023, then surged by 242.46% to $161.7 million in 2024, then slumped by 354.56% to -$411.6 million in 2025, then soared by 187.09% to $358.4 million in 2026.
  • The last three EBITDA figures came in at $358.4 million (Q1 2026), -$411.6 million (Q4 2025), and -$179.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Sarepta Therapeutics 1.84 Bn 1.16 Bn 291.52 Mn 358.43 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 358.43 Mn
Dec 31, 2025 -411.58 Mn
Sep 30, 2025 -179.68 Mn
Jun 30, 2025 196.81 Mn
Mar 31, 2025 -300.39 Mn
Dec 31, 2024 161.68 Mn
Sep 30, 2024 36.89 Mn
Jun 30, 2024 6.12 Mn
Mar 31, 2024 34.51 Mn
Dec 31, 2023 47.21 Mn
Sep 30, 2023 -40.52 Mn
Jun 30, 2023 -24.58 Mn
Mar 31, 2023 -515.51 Mn
Dec 31, 2022 -107.70 Mn
Sep 30, 2022 -258.46 Mn
Jun 30, 2022 -233.66 Mn
Mar 31, 2022 -105.31 Mn
Dec 31, 2021 -121.98 Mn
Sep 30, 2021 -48.17 Mn
Jun 30, 2021 -81.40 Mn