Growth Metrics

Sarepta Therapeutics (SRPT) EBITDA (2016 - 2025)

Sarepta Therapeutics has reported EBITDA over the past 15 years, most recently at -$411.6 million for Q4 2025.

  • For Q4 2025, EBITDA fell 354.56% year-over-year to -$411.6 million; the TTM value through Dec 2025 reached -$694.8 million, down 390.49%, while the annual FY2025 figure was -$699.8 million, 420.88% down from the prior year.
  • EBITDA for Q4 2025 was -$411.6 million at Sarepta Therapeutics, down from -$179.7 million in the prior quarter.
  • Over five years, EBITDA peaked at $196.8 million in Q2 2025 and troughed at -$515.5 million in Q1 2023.
  • A 5-year average of -$105.6 million and a median of -$93.4 million in 2021 define the central range for EBITDA.
  • On a YoY basis, EBITDA climbed as much as 3115.28% in 2025 and fell as far as 970.43% in 2025.
  • Year by year, EBITDA stood at -$122.0 million in 2021, then increased by 11.71% to -$107.7 million in 2022, then soared by 143.83% to $47.2 million in 2023, then skyrocketed by 242.46% to $161.7 million in 2024, then plummeted by 354.56% to -$411.6 million in 2025.
  • Business Quant data shows EBITDA for SRPT at -$411.6 million in Q4 2025, -$179.7 million in Q3 2025, and $196.8 million in Q2 2025.