Growth Metrics

SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025)

SOPHiA GENETICS recorded quarterly Operating Expenses of -$23.3 million in Q4 2025, down 6.17% quarter-over-quarter from -$22.0 million in Q3 2025, and down 6.89% year-over-year from -$25.0 million in Q4 2024.

SOPHiA GENETICS's Operating Expenses history runs 6 years deep, the most recent figure standing at -$23.3 million for Q4 2025.

  • In Q4 2025, Operating Expenses fell 6.89% year-over-year to -$23.3 million; the TTM figure through Dec 2025 stood at -$86.8 million (down 6.71% YoY), while the FY2025 annual figure was -$86.8 million, down 6.71% from the prior year.
  • Operating Expenses came in at -$23.3 million for Q4 2025 at SOPHiA GENETICS, down from -$22.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$14.6 million in Q2 2021 to a low of -$23.9 million in Q1 2022.
  • A 5-year average of -$20.9 million and a median of -$21.8 million in 2023 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses jumped 99.8% in 2021 and sank 62.14% in 2022, its largest moves.
  • SOPHiA GENETICS's Operating Expenses stood at -$19.3 million in 2021, then declined by 7.26% to -$20.7 million in 2022, then dropped by 11.14% to -$23.0 million in 2023, then grew by 5.3% to -$21.8 million in 2024, then dropped by 6.89% to -$23.3 million in 2025.
  • According to Business Quant data, Operating Expenses over the past three periods registered -$23.3 million, -$22.0 million, and -$20.8 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Veeva Systems 30.85 Bn 24.28 Bn 622.47 Mn 376.60 Mn
2 BrightSpring Health Services 12.29 Bn 11.41 Bn 482.22 Mn 360.77 Mn
3 Healthequity 7.80 Bn 7.48 Bn 256.31 Mn 153.36 Mn
4 Hinge Health 4.82 Bn 4.51 Bn 154.23 Mn 122.16 Mn
5 Doximity 4.21 Bn 3.46 Bn 125.97 Mn 101.14 Mn
6 Waystar Holding 4.18 Bn 4.03 Bn 268.04 Mn 233.41 Mn
7 10x Genomics 3.78 Bn 3.24 Bn 106.18 Mn 123.22 Mn
8 Privia Health 2.65 Bn 2.28 Bn 595.71 Mn 596.43 Mn
9 Omnicell 1.95 Bn 1.78 Bn 140.36 Mn 123.51 Mn
10 SOPHiA GENETICS 24.12 Mn -46.17 Mn 14.69 Mn -23.31 Mn

Historic Data

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DateValue
Dec 31, 2025 -23.31 Mn
Sep 30, 2025 -21.96 Mn
Jun 30, 2025 -20.79 Mn
Mar 31, 2025 -20.72 Mn
Dec 31, 2024 -21.81 Mn
Sep 30, 2024 -18.75 Mn
Jun 30, 2024 -18.54 Mn
Mar 31, 2024 -22.22 Mn
Dec 31, 2023 -23.03 Mn
Sep 30, 2023 -21.73 Mn
Jun 30, 2023 -22.93 Mn
Mar 31, 2023 -22.58 Mn
Dec 31, 2022 -20.72 Mn
Sep 30, 2022 -22.93 Mn
Jun 30, 2022 -23.69 Mn
Mar 31, 2022 -23.86 Mn
Dec 31, 2021 -19.32 Mn
Sep 30, 2021 -19.34 Mn
Jun 30, 2021 -14.61 Mn
Mar 31, 2021 -14.81 Mn
Dec 31, 2020 -12.00 Mn
Sep 30, 2020 -9.64 Bn
Jun 30, 2020 -7.29 Bn