SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025)
SOPHiA GENETICS (SOPH) posted Operating Expenses of -$23.3 million for Q4 2025, down 6.17% sequentially from -$22.0 million in Q3 2025, and down 12.77% YoY from -$26.7 million in Q4 2024.
SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has reported Operating Expenses for 6 years, with the latest figure at -$23.3 million in Q4 2025.
- Quarterly Operating Expenses fell 12.77% year-over-year to -$23.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$86.8 million (down 8.23% YoY) and the FY2025 annual result came in at -$86.8 million, down 13.08% from the prior year.
- Operating Expenses retreated to -$23.3 million in Q4 2025 per SOPH's latest filing, from -$22.0 million in the prior quarter.
- Over five years, Operating Expenses peaked at -$14.6 million in Q2 2021 and troughed at -$23.9 million in Q1 2022.
- A 5-year average of -$20.8 million and a median of -$21.3 million in 2023 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2021 and 2022: Operating Expenses surged 99.8% in 2021, then slumped 62.14% in 2022.
- Over 5 years, Operating Expenses stood at -$19.3 million in 2021, then fell by 7.26% to -$20.7 million in 2022, then decreased by 5.5% to -$21.9 million in 2023, then rose by 5.43% to -$20.7 million in 2024, then declined by 12.77% to -$23.3 million in 2025.
- According to Business Quant data, Operating Expenses over the past three periods registered -$23.3 million, -$22.0 million, and -$20.8 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 39.72 Bn | 32.40 Bn | 662.02 Mn | 388.91 Mn |
| 2 | BrightSpring Health Services | 12.19 Bn | 11.64 Bn | 492.75 Mn | 362.36 Mn |
| 3 | Healthequity | 8.79 Bn | 8.52 Bn | 256.31 Mn | 153.36 Mn |
| 4 | 10x Genomics | 7.31 Bn | 6.76 Bn | 112.50 Mn | 132.05 Mn |
| 5 | Hinge Health | 7.10 Bn | 6.71 Bn | 183.95 Mn | 143.51 Mn |
| 6 | MiniMed | 5.66 Bn | 5.36 Bn | 480.00 Mn | 398.00 Mn |
| 7 | Waystar Holding | 4.76 Bn | 4.56 Bn | 221.99 Mn | 243.63 Mn |
| 8 | Doximity | 4.46 Bn | 3.77 Bn | 132.93 Mn | 99.28 Mn |
| 9 | Heartflow | 3.66 Bn | 3.28 Bn | 53.19 Mn | 71.09 Mn |
| 10 | SOPHiA GENETICS | 553.79 Mn | 446.12 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -23.31 Mn |
| Sep 30, 2025 | -21.96 Mn |
| Jun 30, 2025 | -20.79 Mn |
| Mar 31, 2025 | -20.72 Mn |
| Dec 31, 2024 | -20.67 Mn |
| Sep 30, 2024 | -18.75 Mn |
| Jun 30, 2024 | -18.54 Mn |
| Mar 31, 2024 | -22.22 Mn |
| Dec 31, 2023 | -21.86 Mn |
| Sep 30, 2023 | -21.73 Mn |
| Jun 30, 2023 | -22.93 Mn |
| Mar 31, 2023 | -22.58 Mn |
| Dec 31, 2022 | -20.72 Mn |
| Sep 30, 2022 | -22.93 Mn |
| Jun 30, 2022 | -23.69 Mn |
| Mar 31, 2022 | -23.86 Mn |
| Dec 31, 2021 | -19.32 Mn |
| Sep 30, 2021 | -19.34 Mn |
| Jun 30, 2021 | -14.61 Mn |
| Mar 31, 2021 | -14.81 Mn |