SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025)

SOPHiA GENETICS (SOPH) reported Operating Expenses of -$23.3 million for Q4 2025, down 12.77% on a YoY basis from -$26.7 million in Q4 2024, and down 6.17% sequentially from -$22.0 million in Q3 2025.

SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025) Analysis & Trends

SOPHiA GENETICS (SOPH) has 6 years of Operating Expenses data on file, last reported at -$23.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses fell 12.77% year-over-year to -$23.3 million; the trailing twelve-month figure through Dec 2025 stood at -$86.8 million (down 8.23% YoY), and the FY2025 full-year result was -$86.8 million, down 13.08% from the prior year.
  • Operating Expenses retreated to -$23.3 million in Q4 2025, from -$22.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$14.6 million in Q2 2021 to a low of -$23.9 million in Q1 2022.
  • A 5-year average of -$20.8 million and a median of -$21.3 million in 2023 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses soared 99.8% in 2021 and plunged 62.14% in 2022, its largest moves.
  • Tracing SOPH's Operating Expenses over 5 years: stood at -$19.3 million in 2021, then slipped by 7.26% to -$20.7 million in 2022, then declined by 5.5% to -$21.9 million in 2023, then climbed by 5.43% to -$20.7 million in 2024, then decreased by 12.77% to -$23.3 million in 2025.
  • Business Quant data shows SOPH's Operating Expenses at -$23.3 million in Q4 2025, -$22.0 million in Q3 2025, and -$20.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Veeva Systems 32.19 Bn 24.88 Bn 662.02 Mn 388.91 Mn
2 BrightSpring Health Services 14.68 Bn 13.78 Bn 482.22 Mn 360.77 Mn
3 Healthequity 8.43 Bn 8.16 Bn 256.31 Mn 153.36 Mn
4 Hinge Health 5.97 Bn 5.65 Bn 154.23 Mn 122.16 Mn
5 10x Genomics 5.92 Bn 5.38 Bn 106.18 Mn 123.22 Mn
6 MiniMed 4.52 Bn 4.22 Bn 480.00 Mn 398.00 Mn
7 Waystar Holding 4.46 Bn 4.40 Bn 216.84 Mn 233.41 Mn
8 Doximity 3.97 Bn 3.22 Bn 125.97 Mn 101.14 Mn
9 Privia Health 3.11 Bn 2.70 Bn - 596.43 Mn
10 SOPHiA GENETICS 380.25 Mn 309.96 Mn 14.69 Mn -23.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -23.31 Mn
Sep 30, 2025 -21.96 Mn
Jun 30, 2025 -20.79 Mn
Mar 31, 2025 -20.72 Mn
Dec 31, 2024 -20.67 Mn
Sep 30, 2024 -18.75 Mn
Jun 30, 2024 -18.54 Mn
Mar 31, 2024 -22.22 Mn
Dec 31, 2023 -21.86 Mn
Sep 30, 2023 -21.73 Mn
Jun 30, 2023 -22.93 Mn
Mar 31, 2023 -22.58 Mn
Dec 31, 2022 -20.72 Mn
Sep 30, 2022 -22.93 Mn
Jun 30, 2022 -23.69 Mn
Mar 31, 2022 -23.86 Mn
Dec 31, 2021 -19.32 Mn
Sep 30, 2021 -19.34 Mn
Jun 30, 2021 -14.61 Mn
Mar 31, 2021 -14.81 Mn