SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025)
SOPHiA GENETICS's (SOPH) quarterly Operating Expenses came in at -$23.3 million in Q4 2025, down 6.89% year-on-year from -$25.0 million in Q4 2024, and down 6.17% quarter-over-quarter from -$22.0 million in Q3 2025.
SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has disclosed Operating Expenses across 6 years of filings, most recently posting -$23.3 million for Q4 2025.
- Operating Expenses for Q4 2025 came in at -$23.3 million, down 6.89% year-over-year; the trailing twelve-month figure through Dec 2025 was -$86.8 million (down 6.71% YoY), and the FY2025 annual result was -$86.8 million, down 6.71% from the prior year.
- Operating Expenses came in at -$23.3 million for Q4 2025 at SOPHiA GENETICS, down from -$22.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of -$14.6 million in Q2 2021 to a low of -$23.9 million in Q1 2022.
- The 5-year median for Operating Expenses is -$21.8 million (2023), against an average of -$20.9 million.
- Across the five-year window, Operating Expenses soared 99.8% in 2021 and slumped 62.14% in 2022, its largest moves.
- SOPHiA GENETICS's Operating Expenses stood at -$19.3 million in 2021, then dropped by 7.26% to -$20.7 million in 2022, then slipped by 11.14% to -$23.0 million in 2023, then climbed by 5.3% to -$21.8 million in 2024, then slipped by 6.89% to -$23.3 million in 2025.
- The last three Operating Expenses figures came in at -$23.3 million (Q4 2025), -$22.0 million (Q3 2025), and -$20.8 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 24.83 Bn | 17.52 Bn | 662.02 Mn | 388.91 Mn |
| 2 | BrightSpring Health Services | 13.57 Bn | 12.69 Bn | 482.22 Mn | 360.77 Mn |
| 3 | Healthequity | 7.20 Bn | 6.93 Bn | 256.31 Mn | 153.36 Mn |
| 4 | Hinge Health | 5.42 Bn | 5.11 Bn | 154.23 Mn | 122.16 Mn |
| 5 | 10x Genomics | 4.46 Bn | 3.92 Bn | 106.18 Mn | 123.22 Mn |
| 6 | Doximity | 3.81 Bn | 3.06 Bn | 125.97 Mn | 101.14 Mn |
| 7 | Waystar Holding | 3.52 Bn | 3.36 Bn | 268.04 Mn | 233.41 Mn |
| 8 | Privia Health | 2.94 Bn | 2.57 Bn | 595.71 Mn | 596.43 Mn |
| 9 | Omnicell | 1.76 Bn | 1.59 Bn | 140.36 Mn | 123.51 Mn |
| 10 | SOPHiA GENETICS | 26.19 Mn | -44.10 Mn | 14.69 Mn | -23.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -23.31 Mn |
| Sep 30, 2025 | -21.96 Mn |
| Jun 30, 2025 | -20.79 Mn |
| Mar 31, 2025 | -20.72 Mn |
| Dec 31, 2024 | -21.81 Mn |
| Sep 30, 2024 | -18.75 Mn |
| Jun 30, 2024 | -18.54 Mn |
| Mar 31, 2024 | -22.22 Mn |
| Dec 31, 2023 | -23.03 Mn |
| Sep 30, 2023 | -21.73 Mn |
| Jun 30, 2023 | -22.93 Mn |
| Mar 31, 2023 | -22.58 Mn |
| Dec 31, 2022 | -20.72 Mn |
| Sep 30, 2022 | -22.93 Mn |
| Jun 30, 2022 | -23.69 Mn |
| Mar 31, 2022 | -23.86 Mn |
| Dec 31, 2021 | -19.32 Mn |
| Sep 30, 2021 | -19.34 Mn |
| Jun 30, 2021 | -14.61 Mn |
| Mar 31, 2021 | -14.81 Mn |