SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025)

SOPHiA GENETICS's (SOPH) quarterly Operating Expenses came in at -$23.3 million in Q4 2025, down 6.89% year-on-year from -$25.0 million in Q4 2024, and down 6.17% quarter-over-quarter from -$22.0 million in Q3 2025.

SOPHiA GENETICS (SOPH) Operating Expenses (2020 - 2025) Analysis & Trends

SOPHiA GENETICS has disclosed Operating Expenses across 6 years of filings, most recently posting -$23.3 million for Q4 2025.

  • Operating Expenses for Q4 2025 came in at -$23.3 million, down 6.89% year-over-year; the trailing twelve-month figure through Dec 2025 was -$86.8 million (down 6.71% YoY), and the FY2025 annual result was -$86.8 million, down 6.71% from the prior year.
  • Operating Expenses came in at -$23.3 million for Q4 2025 at SOPHiA GENETICS, down from -$22.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$14.6 million in Q2 2021 to a low of -$23.9 million in Q1 2022.
  • The 5-year median for Operating Expenses is -$21.8 million (2023), against an average of -$20.9 million.
  • Across the five-year window, Operating Expenses soared 99.8% in 2021 and slumped 62.14% in 2022, its largest moves.
  • SOPHiA GENETICS's Operating Expenses stood at -$19.3 million in 2021, then dropped by 7.26% to -$20.7 million in 2022, then slipped by 11.14% to -$23.0 million in 2023, then climbed by 5.3% to -$21.8 million in 2024, then slipped by 6.89% to -$23.3 million in 2025.
  • The last three Operating Expenses figures came in at -$23.3 million (Q4 2025), -$22.0 million (Q3 2025), and -$20.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 388.91 Mn
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 360.77 Mn
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 153.36 Mn
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 122.16 Mn
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn 123.22 Mn
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 101.14 Mn
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 233.41 Mn
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 596.43 Mn
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 123.51 Mn
10 SOPHiA GENETICS 26.19 Mn -44.10 Mn 14.69 Mn -23.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -23.31 Mn
Sep 30, 2025 -21.96 Mn
Jun 30, 2025 -20.79 Mn
Mar 31, 2025 -20.72 Mn
Dec 31, 2024 -21.81 Mn
Sep 30, 2024 -18.75 Mn
Jun 30, 2024 -18.54 Mn
Mar 31, 2024 -22.22 Mn
Dec 31, 2023 -23.03 Mn
Sep 30, 2023 -21.73 Mn
Jun 30, 2023 -22.93 Mn
Mar 31, 2023 -22.58 Mn
Dec 31, 2022 -20.72 Mn
Sep 30, 2022 -22.93 Mn
Jun 30, 2022 -23.69 Mn
Mar 31, 2022 -23.86 Mn
Dec 31, 2021 -19.32 Mn
Sep 30, 2021 -19.34 Mn
Jun 30, 2021 -14.61 Mn
Mar 31, 2021 -14.81 Mn