SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025)

SOPHiA GENETICS's (SOPH) quarterly EBT Margin came in at 90.17% in Q4 2025, down 817.0% year-on-year from 12.58% in Q4 2024, and up 9.44% quarter-over-quarter from 99.57% in Q3 2025.

SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025) Analysis & Trends

SOPHiA GENETICS has disclosed EBT Margin across 6 years of filings, most recently posting 90.17% for Q4 2025.

  • EBT Margin for Q4 2025 came in at 90.17%, down 817.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 100.28% (down 627.0% YoY), and the FY2025 annual result was 100.28%, down 627.0% from the prior year.
  • EBT Margin came in at 90.17% for Q4 2025 at SOPHiA GENETICS, up from 99.57% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 82.01% in Q4 2024 to a low of 232.52% in Q1 2022.
  • The 5-year median for EBT Margin is 128.68% (2025), against an average of 137.89%.
  • Across the five-year window, EBT Margin tumbled 9334 bps in 2022 and jumped 11806 bps in 2023, its largest moves.
  • SOPHiA GENETICS's EBT Margin stood at 200.23% in 2021, then jumped by 47 bps to 106.31% in 2022, then tumbled by 33 bps to 141.08% in 2023, then surged by 42 bps to 82.01% in 2024, then slipped by 10 bps to 90.17% in 2025.
  • The last three EBT Margin figures came in at 90.17% (Q4 2025), 99.57% (Q3 2025), and 118.17% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 39.36%
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 2.29%
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 26.06%
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 19.72%
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn -8.52%
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 22.10%
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 19.06%
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 1.54%
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 5.46%
10 SOPHiA GENETICS 26.19 Mn -44.10 Mn 14.69 Mn -90.17%

Historic Data

Download Data
DateValue
Dec 31, 2025 -90.17%
Sep 30, 2025 -99.57%
Jun 30, 2025 -118.17%
Mar 31, 2025 -94.95%
Dec 31, 2024 -82.01%
Sep 30, 2024 -115.49%
Jun 30, 2024 -95.09%
Mar 31, 2024 -84.85%
Dec 31, 2023 -141.08%
Sep 30, 2023 -82.96%
Jun 30, 2023 -141.64%
Mar 31, 2023 -140.29%
Dec 31, 2022 -106.31%
Sep 30, 2022 -201.02%
Jun 30, 2022 -211.60%
Mar 31, 2022 -232.52%
Dec 31, 2021 -200.23%
Sep 30, 2021 -200.45%
Jun 30, 2021 -180.29%
Mar 31, 2021 -139.18%