SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025)
SOPHiA GENETICS recorded quarterly EBT Margin of 90.17% in Q4 2025, up 9.44% quarter-over-quarter from 99.57% in Q3 2025, and down 817.0% year-over-year from 12.58% in Q4 2024.
SOPHiA GENETICS's EBT Margin history runs 6 years deep, the most recent figure standing at 90.17% for Q4 2025.
- In Q4 2025, EBT Margin fell 817.0% year-over-year to 90.17%; the TTM figure through Dec 2025 stood at 100.28% (down 627.0% YoY), while the FY2025 annual figure was 100.28%, down 627.0% from the prior year.
- EBT Margin came in at 90.17% for Q4 2025 at SOPHiA GENETICS, up from 99.57% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 82.01% in Q4 2024 to a low of 232.52% in Q1 2022.
- A 5-year average of 137.89% and a median of 128.68% in 2025 frame the typical range for EBT Margin.
- Across the five-year window, EBT Margin slumped 9334 bps in 2022 and surged 11806 bps in 2023, its largest moves.
- SOPHiA GENETICS's EBT Margin stood at 200.23% in 2021, then surged by 47 bps to 106.31% in 2022, then slumped by 33 bps to 141.08% in 2023, then soared by 42 bps to 82.01% in 2024, then dropped by 10 bps to 90.17% in 2025.
- According to Business Quant data, EBT Margin over the past three periods registered 90.17%, 99.57%, and 118.17% for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 30.85 Bn | 24.28 Bn | 622.47 Mn | 37.99% |
| 2 | BrightSpring Health Services | 12.29 Bn | 11.41 Bn | 482.22 Mn | 2.29% |
| 3 | Healthequity | 7.80 Bn | 7.48 Bn | 256.31 Mn | 26.06% |
| 4 | Hinge Health | 4.82 Bn | 4.51 Bn | 154.23 Mn | 19.72% |
| 5 | Doximity | 4.21 Bn | 3.46 Bn | 125.97 Mn | 22.10% |
| 6 | Waystar Holding | 4.18 Bn | 4.03 Bn | 268.04 Mn | 19.06% |
| 7 | 10x Genomics | 3.78 Bn | 3.24 Bn | 106.18 Mn | -8.52% |
| 8 | Privia Health | 2.65 Bn | 2.28 Bn | 595.71 Mn | 1.54% |
| 9 | Omnicell | 1.95 Bn | 1.78 Bn | 140.36 Mn | 5.46% |
| 10 | SOPHiA GENETICS | 24.12 Mn | -46.17 Mn | 14.69 Mn | -90.17% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -90.17% |
| Sep 30, 2025 | -99.57% |
| Jun 30, 2025 | -118.17% |
| Mar 31, 2025 | -94.95% |
| Dec 31, 2024 | -82.01% |
| Sep 30, 2024 | -115.49% |
| Jun 30, 2024 | -95.09% |
| Mar 31, 2024 | -84.85% |
| Dec 31, 2023 | -141.08% |
| Sep 30, 2023 | -82.96% |
| Jun 30, 2023 | -141.64% |
| Mar 31, 2023 | -140.29% |
| Dec 31, 2022 | -106.31% |
| Sep 30, 2022 | -201.02% |
| Jun 30, 2022 | -211.60% |
| Mar 31, 2022 | -232.52% |
| Dec 31, 2021 | -200.23% |
| Sep 30, 2021 | -200.45% |
| Jun 30, 2021 | -180.29% |
| Mar 31, 2021 | -139.18% |
| Dec 31, 2020 | -158.25% |
| Sep 30, 2020 | -146.07% |
| Jun 30, 2020 | -132.47% |