SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025)
SOPHiA GENETICS's (SOPH) quarterly EBT Margin came in at 90.17% in Q4 2025, down 817.0% year-on-year from 12.58% in Q4 2024, and up 9.44% quarter-over-quarter from 99.57% in Q3 2025.
SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has disclosed EBT Margin across 6 years of filings, most recently posting 90.17% for Q4 2025.
- EBT Margin for Q4 2025 came in at 90.17%, down 817.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 100.28% (down 627.0% YoY), and the FY2025 annual result was 100.28%, down 627.0% from the prior year.
- EBT Margin came in at 90.17% for Q4 2025 at SOPHiA GENETICS, up from 99.57% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 82.01% in Q4 2024 to a low of 232.52% in Q1 2022.
- The 5-year median for EBT Margin is 128.68% (2025), against an average of 137.89%.
- Across the five-year window, EBT Margin tumbled 9334 bps in 2022 and jumped 11806 bps in 2023, its largest moves.
- SOPHiA GENETICS's EBT Margin stood at 200.23% in 2021, then jumped by 47 bps to 106.31% in 2022, then tumbled by 33 bps to 141.08% in 2023, then surged by 42 bps to 82.01% in 2024, then slipped by 10 bps to 90.17% in 2025.
- The last three EBT Margin figures came in at 90.17% (Q4 2025), 99.57% (Q3 2025), and 118.17% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 24.83 Bn | 17.52 Bn | 662.02 Mn | 39.36% |
| 2 | BrightSpring Health Services | 13.57 Bn | 12.69 Bn | 482.22 Mn | 2.29% |
| 3 | Healthequity | 7.20 Bn | 6.93 Bn | 256.31 Mn | 26.06% |
| 4 | Hinge Health | 5.42 Bn | 5.11 Bn | 154.23 Mn | 19.72% |
| 5 | 10x Genomics | 4.46 Bn | 3.92 Bn | 106.18 Mn | -8.52% |
| 6 | Doximity | 3.81 Bn | 3.06 Bn | 125.97 Mn | 22.10% |
| 7 | Waystar Holding | 3.52 Bn | 3.36 Bn | 268.04 Mn | 19.06% |
| 8 | Privia Health | 2.94 Bn | 2.57 Bn | 595.71 Mn | 1.54% |
| 9 | Omnicell | 1.76 Bn | 1.59 Bn | 140.36 Mn | 5.46% |
| 10 | SOPHiA GENETICS | 26.19 Mn | -44.10 Mn | 14.69 Mn | -90.17% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -90.17% |
| Sep 30, 2025 | -99.57% |
| Jun 30, 2025 | -118.17% |
| Mar 31, 2025 | -94.95% |
| Dec 31, 2024 | -82.01% |
| Sep 30, 2024 | -115.49% |
| Jun 30, 2024 | -95.09% |
| Mar 31, 2024 | -84.85% |
| Dec 31, 2023 | -141.08% |
| Sep 30, 2023 | -82.96% |
| Jun 30, 2023 | -141.64% |
| Mar 31, 2023 | -140.29% |
| Dec 31, 2022 | -106.31% |
| Sep 30, 2022 | -201.02% |
| Jun 30, 2022 | -211.60% |
| Mar 31, 2022 | -232.52% |
| Dec 31, 2021 | -200.23% |
| Sep 30, 2021 | -200.45% |
| Jun 30, 2021 | -180.29% |
| Mar 31, 2021 | -139.18% |