SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025)
SOPHiA GENETICS (SOPH) posted EBT Margin of 90.17% for Q4 2025, up 9.44% sequentially from 99.57% in Q3 2025, and down 817.0% YoY from 12.58% in Q4 2024.
SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has reported EBT Margin for 6 years, with the latest figure at 90.17% in Q4 2025.
- Quarterly EBT Margin fell 817.0% year-over-year to 90.17% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 100.28% (down 627.0% YoY) and the FY2025 annual result came in at 100.28%, down 627.0% from the prior year.
- EBT Margin advanced to 90.17% in Q4 2025 per SOPH's latest filing, from 99.57% in the prior quarter.
- Over five years, EBT Margin peaked at 82.01% in Q4 2024 and troughed at 232.52% in Q1 2022.
- A 5-year average of 137.89% and a median of 128.68% in 2025 frame the typical range for EBT Margin.
- The sharpest annual moves came in 2021 and 2022: EBT Margin jumped 2000000000 bps in 2021, then tumbled 9334 bps in 2022.
- Over 5 years, EBT Margin stood at 200.23% in 2021, then soared by 47 bps to 106.31% in 2022, then tumbled by 33 bps to 141.08% in 2023, then jumped by 42 bps to 82.01% in 2024, then declined by 10 bps to 90.17% in 2025.
- According to Business Quant data, EBT Margin over the past three periods registered 90.17%, 99.57%, and 118.17% for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 39.72 Bn | 32.40 Bn | 662.02 Mn | 39.36% |
| 2 | BrightSpring Health Services | 12.19 Bn | 11.64 Bn | 492.75 Mn | 2.41% |
| 3 | Healthequity | 8.79 Bn | 8.52 Bn | 256.31 Mn | 26.06% |
| 4 | 10x Genomics | 7.31 Bn | 6.76 Bn | 112.50 Mn | -12.34% |
| 5 | Hinge Health | 7.10 Bn | 6.71 Bn | 183.95 Mn | 20.88% |
| 6 | MiniMed | 5.66 Bn | 5.36 Bn | 480.00 Mn | -10.99% |
| 7 | Waystar Holding | 4.76 Bn | 4.56 Bn | 221.99 Mn | 17.64% |
| 8 | Doximity | 4.46 Bn | 3.77 Bn | 132.93 Mn | 25.77% |
| 9 | Heartflow | 3.66 Bn | 3.28 Bn | 53.19 Mn | -24.53% |
| 10 | SOPHiA GENETICS | 553.79 Mn | 446.12 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -90.17% |
| Sep 30, 2025 | -99.57% |
| Jun 30, 2025 | -118.17% |
| Mar 31, 2025 | -94.95% |
| Dec 31, 2024 | -82.01% |
| Sep 30, 2024 | -115.49% |
| Jun 30, 2024 | -95.09% |
| Mar 31, 2024 | -84.85% |
| Dec 31, 2023 | -141.08% |
| Sep 30, 2023 | -82.96% |
| Jun 30, 2023 | -141.64% |
| Mar 31, 2023 | -140.29% |
| Dec 31, 2022 | -106.31% |
| Sep 30, 2022 | -201.02% |
| Jun 30, 2022 | -211.60% |
| Mar 31, 2022 | -232.52% |
| Dec 31, 2021 | -200.23% |
| Sep 30, 2021 | -200.45% |
| Jun 30, 2021 | -180.29% |
| Mar 31, 2021 | -139.18% |