SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025)
SOPHiA GENETICS (SOPH) reported EBT Margin of 90.17% for Q4 2025, down 817.0% on a YoY basis from 12.58% in Q4 2024, and up 9.44% sequentially from 99.57% in Q3 2025.
SOPHiA GENETICS (SOPH) EBT Margin (2020 - 2025) Analysis & Trends
SOPHiA GENETICS (SOPH) has 6 years of EBT Margin data on file, last reported at 90.17% in Q4 2025.
- For the quarter ending Q4 2025, EBT Margin fell 817.0% year-over-year to 90.17%; the trailing twelve-month figure through Dec 2025 stood at 100.28% (down 627.0% YoY), and the FY2025 full-year result was 100.28%, down 627.0% from the prior year.
- EBT Margin advanced to 90.17% in Q4 2025, from 99.57% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 82.01% in Q4 2024 to a low of 232.52% in Q1 2022.
- A 5-year average of 137.89% and a median of 128.68% in 2025 frame the typical range for EBT Margin.
- Across the five-year window, EBT Margin sank 9334 bps in 2022 and jumped 11806 bps in 2023, its largest moves.
- Tracing SOPH's EBT Margin over 5 years: stood at 200.23% in 2021, then soared by 47 bps to 106.31% in 2022, then plunged by 33 bps to 141.08% in 2023, then jumped by 42 bps to 82.01% in 2024, then decreased by 10 bps to 90.17% in 2025.
- Business Quant data shows SOPH's EBT Margin at 90.17% in Q4 2025, 99.57% in Q3 2025, and 118.17% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 29.34 Bn | 22.03 Bn | 662.02 Mn | 39.36% |
| 2 | BrightSpring Health Services | 13.49 Bn | 12.59 Bn | 482.22 Mn | 2.29% |
| 3 | Healthequity | 7.96 Bn | 7.70 Bn | 256.31 Mn | 26.06% |
| 4 | 10x Genomics | 6.17 Bn | 5.63 Bn | 106.18 Mn | -8.52% |
| 5 | Hinge Health | 6.02 Bn | 5.70 Bn | 154.23 Mn | 19.72% |
| 6 | MiniMed | 4.19 Bn | 3.89 Bn | 480.00 Mn | -10.99% |
| 7 | Waystar Holding | 4.14 Bn | 4.07 Bn | 216.84 Mn | 19.06% |
| 8 | Doximity | 3.82 Bn | 3.08 Bn | 125.97 Mn | 22.10% |
| 9 | Privia Health | 3.10 Bn | 2.73 Bn | - | 1.54% |
| 10 | SOPHiA GENETICS | 408.62 Mn | 338.33 Mn | 14.69 Mn | -90.17% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -90.17% |
| Sep 30, 2025 | -99.57% |
| Jun 30, 2025 | -118.17% |
| Mar 31, 2025 | -94.95% |
| Dec 31, 2024 | -82.01% |
| Sep 30, 2024 | -115.49% |
| Jun 30, 2024 | -95.09% |
| Mar 31, 2024 | -84.85% |
| Dec 31, 2023 | -141.08% |
| Sep 30, 2023 | -82.96% |
| Jun 30, 2023 | -141.64% |
| Mar 31, 2023 | -140.29% |
| Dec 31, 2022 | -106.31% |
| Sep 30, 2022 | -201.02% |
| Jun 30, 2022 | -211.60% |
| Mar 31, 2022 | -232.52% |
| Dec 31, 2021 | -200.23% |
| Sep 30, 2021 | -200.45% |
| Jun 30, 2021 | -180.29% |
| Mar 31, 2021 | -139.18% |