SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025)
SOPHiA GENETICS's (SOPH) quarterly EBITDA Margin came in at 85.3% in Q4 2025, down 3426.0% year-on-year from 2.56% in Q4 2024, and up 7.06% quarter-over-quarter from 91.78% in Q3 2025.
SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has disclosed EBITDA Margin across 6 years of filings, most recently posting 85.3% for Q4 2025.
- EBITDA Margin for Q4 2025 came in at 85.3%, down 3426.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 91.76% (down 250.0% YoY), and the FY2025 annual result was 91.76%, down 3011.0% from the prior year.
- EBITDA Margin came in at 85.3% for Q4 2025 at SOPHiA GENETICS, up from 91.78% in the prior quarter.
- In the past five years, EBITDA Margin ranged from a high of 51.04% in Q4 2024 to a low of 197914856.65% in Q3 2021.
- The 5-year median for EBITDA Margin is 115.78% (2024), against an average of 9895864.4%.
- Across the five-year window, EBITDA Margin slumped 2000000000 bps in 2021 and soared 2000000000 bps in 2022, its largest moves.
- SOPHiA GENETICS's EBITDA Margin stood at 192.09% in 2021, then jumped by 41 bps to 112.69% in 2022, then soared by 37 bps to 71.25% in 2023, then climbed by 28 bps to 51.04% in 2024, then slumped by 67 bps to 85.3% in 2025.
- The last three EBITDA Margin figures came in at 85.3% (Q4 2025), 91.78% (Q3 2025), and 100.92% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 24.83 Bn | 17.52 Bn | 662.02 Mn | 26.39% |
| 2 | BrightSpring Health Services | 13.57 Bn | 12.69 Bn | 482.22 Mn | 3.36% |
| 3 | Healthequity | 7.20 Bn | 6.93 Bn | 256.31 Mn | 29.03% |
| 4 | Hinge Health | 5.42 Bn | 5.11 Bn | 154.23 Mn | 19.09% |
| 5 | 10x Genomics | 4.46 Bn | 3.92 Bn | 106.18 Mn | -11.30% |
| 6 | Doximity | 3.81 Bn | 3.06 Bn | 125.97 Mn | 17.08% |
| 7 | Waystar Holding | 3.52 Bn | 3.36 Bn | 268.04 Mn | 27.87% |
| 8 | Privia Health | 2.94 Bn | 2.57 Bn | 595.71 Mn | 1.25% |
| 9 | Omnicell | 1.76 Bn | 1.59 Bn | 140.36 Mn | 5.44% |
| 10 | SOPHiA GENETICS | 26.19 Mn | -44.10 Mn | 14.69 Mn | -85.30% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -91.78% |
| Jun 30, 2025 | -100.92% |
| Mar 31, 2025 | -90.20% |
| Dec 31, 2024 | -51.04% |
| Sep 30, 2024 | -96.91% |
| Jun 30, 2024 | -94.92% |
| Mar 31, 2024 | -118.87% |
| Dec 31, 2023 | -71.25% |
| Sep 30, 2023 | -101.48% |
| Jun 30, 2023 | -133.17% |
| Mar 31, 2023 | -138.10% |
| Dec 31, 2022 | -112.69% |
| Sep 30, 2022 | -202.94% |
| Jun 30, 2022 | -206.39% |
| Mar 31, 2022 | -230.37% |
| Dec 31, 2021 | -192.09% |
| Sep 30, 2021 | -197,914,856.65% |
| Jun 30, 2021 | -156.46% |
| Mar 31, 2021 | -156.57% |