SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025)

SOPHiA GENETICS's (SOPH) quarterly EBITDA Margin came in at 85.3% in Q4 2025, down 3426.0% year-on-year from 2.56% in Q4 2024, and up 7.06% quarter-over-quarter from 91.78% in Q3 2025.

SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025) Analysis & Trends

SOPHiA GENETICS has disclosed EBITDA Margin across 6 years of filings, most recently posting 85.3% for Q4 2025.

  • EBITDA Margin for Q4 2025 came in at 85.3%, down 3426.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 91.76% (down 250.0% YoY), and the FY2025 annual result was 91.76%, down 3011.0% from the prior year.
  • EBITDA Margin came in at 85.3% for Q4 2025 at SOPHiA GENETICS, up from 91.78% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 51.04% in Q4 2024 to a low of 197914856.65% in Q3 2021.
  • The 5-year median for EBITDA Margin is 115.78% (2024), against an average of 9895864.4%.
  • Across the five-year window, EBITDA Margin slumped 2000000000 bps in 2021 and soared 2000000000 bps in 2022, its largest moves.
  • SOPHiA GENETICS's EBITDA Margin stood at 192.09% in 2021, then jumped by 41 bps to 112.69% in 2022, then soared by 37 bps to 71.25% in 2023, then climbed by 28 bps to 51.04% in 2024, then slumped by 67 bps to 85.3% in 2025.
  • The last three EBITDA Margin figures came in at 85.3% (Q4 2025), 91.78% (Q3 2025), and 100.92% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 26.39%
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 3.36%
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 29.03%
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 19.09%
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn -11.30%
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 17.08%
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 27.87%
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 1.25%
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 5.44%
10 SOPHiA GENETICS 26.19 Mn -44.10 Mn 14.69 Mn -85.30%

Historic Data

Download Data
DateValue
Dec 31, 2025 -85.30%
Sep 30, 2025 -91.78%
Jun 30, 2025 -100.92%
Mar 31, 2025 -90.20%
Dec 31, 2024 -51.04%
Sep 30, 2024 -96.91%
Jun 30, 2024 -94.92%
Mar 31, 2024 -118.87%
Dec 31, 2023 -71.25%
Sep 30, 2023 -101.48%
Jun 30, 2023 -133.17%
Mar 31, 2023 -138.10%
Dec 31, 2022 -112.69%
Sep 30, 2022 -202.94%
Jun 30, 2022 -206.39%
Mar 31, 2022 -230.37%
Dec 31, 2021 -192.09%
Sep 30, 2021 -197,914,856.65%
Jun 30, 2021 -156.46%
Mar 31, 2021 -156.57%