SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025)
SOPHiA GENETICS (SOPH) posted EBITDA Margin of 85.3% for Q4 2025, up 7.06% sequentially from 91.78% in Q3 2025, and down 3426.0% YoY from 2.56% in Q4 2024.
SOPHiA GENETICS (SOPH) EBITDA Margin (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has reported EBITDA Margin for 6 years, with the latest figure at 85.3% in Q4 2025.
- Quarterly EBITDA Margin fell 3426.0% year-over-year to 85.3% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 91.76% (down 250.0% YoY) and the FY2025 annual result came in at 91.76%, down 3011.0% from the prior year.
- EBITDA Margin grew to 85.3% in Q4 2025 per SOPH's latest filing, from 91.78% in the prior quarter.
- Over five years, EBITDA Margin peaked at 51.04% in Q4 2024 and troughed at 156455099.23% in Q2 2021.
- A 5-year average of 7822878.61% and a median of 115.78% in 2024 frame the typical range for EBITDA Margin.
- The sharpest annual moves came in 2021 and 2022: EBITDA Margin tumbled 2000000000 bps in 2021, then jumped 2000000000 bps in 2022.
- Over 5 years, EBITDA Margin stood at 192.09% in 2021, then soared by 41 bps to 112.69% in 2022, then surged by 37 bps to 71.25% in 2023, then increased by 28 bps to 51.04% in 2024, then slumped by 67 bps to 85.3% in 2025.
- According to Business Quant data, EBITDA Margin over the past three periods registered 85.3%, 91.78%, and 100.92% for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 39.72 Bn | 32.40 Bn | 662.02 Mn | 30.93% |
| 2 | BrightSpring Health Services | 12.19 Bn | 11.64 Bn | 492.75 Mn | 3.37% |
| 3 | Healthequity | 8.79 Bn | 8.52 Bn | 256.31 Mn | 29.03% |
| 4 | 10x Genomics | 7.31 Bn | 6.76 Bn | 112.50 Mn | -12.95% |
| 5 | Hinge Health | 7.10 Bn | 6.71 Bn | 183.95 Mn | 19.00% |
| 6 | MiniMed | 5.66 Bn | 5.36 Bn | 480.00 Mn | -11.11% |
| 7 | Waystar Holding | 4.76 Bn | 4.56 Bn | 221.99 Mn | 23.79% |
| 8 | Doximity | 4.46 Bn | 3.77 Bn | 132.93 Mn | 21.48% |
| 9 | Heartflow | 3.66 Bn | 3.28 Bn | 53.19 Mn | -27.93% |
| 10 | SOPHiA GENETICS | 553.79 Mn | 446.12 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -91.78% |
| Jun 30, 2025 | -100.92% |
| Mar 31, 2025 | -90.20% |
| Dec 31, 2024 | -51.04% |
| Sep 30, 2024 | -96.91% |
| Jun 30, 2024 | -94.92% |
| Mar 31, 2024 | -118.87% |
| Dec 31, 2023 | -71.25% |
| Sep 30, 2023 | -101.48% |
| Jun 30, 2023 | -133.17% |
| Mar 31, 2023 | -138.10% |
| Dec 31, 2022 | -112.69% |
| Sep 30, 2022 | -202.94% |
| Jun 30, 2022 | -206.39% |
| Mar 31, 2022 | -230.37% |
| Dec 31, 2021 | -192.09% |
| Sep 30, 2021 | -197.91% |
| Jun 30, 2021 | -156,455,099.23% |
| Mar 31, 2021 | -156.57% |