Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.39 -0.05 (-10.87%)
At close: Aug 21, 2026 · 4:00 PM EDT

Senti Biosciences Holdings (SNTI) Retained Earnings (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly Retained Earnings of -$358.6 million for Q4 2025, down 20.7% year-over-year from -$452.2 million in Q4 2024, and down 4.21% quarter-over-quarter from -$344.1 million in Q3 2025.

Senti Biosciences Holdings (SNTI) Retained Earnings (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Retained Earnings history runs 5 years deep, the most recent figure standing at -$358.6 million for Q4 2025.

  • In Q4 2025, Retained Earnings fell 20.7% year-over-year to -$358.6 million; the TTM figure through Dec 2025 stood at -$358.6 million (down 20.7% YoY), while the FY2025 annual figure was -$358.6 million, down 20.7% from the prior year.
  • Retained Earnings for Q4 2025 stood at -$358.6 million, down from -$344.1 million in the prior quarter.
  • The five-year high for Retained Earnings was $349.1 million in Q1 2025, with the low at -$358.6 million in Q4 2025.
  • The 5-year median for Retained Earnings is -$218.2 million (2023), against an average of -$118.6 million.
  • Peak annual rise in Retained Earnings reached 361.12% in 2022, while the deepest fall reached 2122.82% in 2022.
  • Senti Biosciences Holdings' Retained Earnings stood at -$115.1 million in 2021, then soared by 361.12% to $300.5 million in 2022, then tumbled by 181.29% to -$244.3 million in 2023, then retreated by 21.61% to -$297.1 million in 2024, then dropped by 20.7% to -$358.6 million in 2025.
  • Business Quant data shows SNTI's Retained Earnings at -$358.6 million in Q4 2025, -$344.1 million in Q3 2025, and -$326.0 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 15.69 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 37.62 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 558.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 5.10 Bn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 13.05 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -6.33 Bn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 20.91 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 6.57 Bn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 4.38 Bn
10 Senti Biosciences Holdings 12.06 Mn 12.06 Mn - -375.54 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -358.60 Mn
Sep 30, 2025 -344.10 Mn
Jun 30, 2025 -326.00 Mn
Mar 31, 2025 349.10 Mn
Dec 31, 2024 -297.10 Mn
Sep 30, 2024 -296.50 Mn
Jun 30, 2024 -267.70 Mn
Mar 31, 2024 -256.50 Mn
Dec 31, 2023 -244.30 Mn
Mar 31, 2023 -192.01 Mn
Dec 31, 2022 300.54 Mn
Sep 30, 2022 295.42 Mn
Jun 30, 2022 -138.40 Mn
Dec 31, 2021 -115.10 Mn
Jun 30, 2021 -6.23 Mn
Mar 31, 2021 24,425.00