Senti Biosciences (SNTI) Retained Earnings (2021 - 2025)

Senti Biosciences' quarterly Retained Earnings came in at -$358.6 million in Q4 2025, down 20.69% year-on-year from -$452.1 million in Q4 2024, and down 4.21% quarter-over-quarter from -$344.1 million in Q3 2025.

Senti Biosciences has reported Retained Earnings for 5 years, with the latest figure at -$358.6 million in Q4 2025.

  • For the quarter ending Q4 2025, Retained Earnings fell 20.69% year-over-year to -$358.6 million; the trailing twelve-month figure through Dec 2025 stood at -$358.6 million (down 20.69% YoY), and the FY2025 full-year result was -$358.6 million, down 20.69% from the prior year.
  • Retained Earnings for Q4 2025 stood at -$358.6 million, down from -$344.1 million in the prior quarter.
  • The five-year high for Retained Earnings was -$1178.0 in Q1 2021, with the low at -$358.6 million in Q4 2025.
  • Average Retained Earnings over 5 years is -$194.4 million, with a median of -$218.2 million recorded in 2023.
  • Year-over-year, Retained Earnings tumbled 864587.1% in 2022 and fell 16.06% in 2025.
  • Tracing SNTI's Retained Earnings over 5 years: stood at -$115.1 million in 2021, then plunged by 50.55% to -$173.3 million in 2022, then tumbled by 41.01% to -$244.3 million in 2023, then dropped by 21.6% to -$297.1 million in 2024, then decreased by 20.69% to -$358.6 million in 2025.
  • The last three Retained Earnings figures came in at -$358.6 million (Q4 2025), -$344.1 million (Q3 2025), and -$326.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -358.60 Mn
Sep 30, 2025 -344.11 Mn
Jun 30, 2025 -326.00 Mn
Mar 31, 2025 -311.25 Mn
Dec 31, 2024 -297.13 Mn
Sep 30, 2024 -296.50 Mn
Jun 30, 2024 -267.66 Mn
Mar 31, 2024 -256.46 Mn
Dec 31, 2023 -244.34 Mn
Mar 31, 2023 -192.00 Mn
Dec 31, 2022 -173.29 Mn
Sep 30, 2022 -155.08 Mn
Jun 30, 2022 -138.44 Mn
Mar 31, 2022 -10.19 Mn
Dec 31, 2021 -115.10 Mn
Sep 30, 2021 -6.52 Mn
Jun 30, 2021 -6.23 Mn
Mar 31, 2021 -1,178.00