Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.39 -0.05 (-10.87%)
At close: Aug 21, 2026 · 4:00 PM EDT

Senti Biosciences Holdings (SNTI) Net Income (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly Net Income of -$117.4 million for Q4 2025, down 341.37% quarter-over-quarter from -$26.6 million in Q3 2025.

Senti Biosciences Holdings (SNTI) Net Income (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Net Income history runs 4 years deep, the most recent figure standing at -$117.4 million for Q4 2025.

  • In Q4 2025, Net Income changed N/A year-over-year to -$117.4 million; the TTM figure through Dec 2025 stood at -$223.9 million (changed N/A YoY), while the FY2025 annual figure was -$167.5 million, changed N/A from the prior year.
  • Net Income for Q4 2025 stood at -$117.4 million, down from -$26.6 million in the prior quarter.
  • The five-year high for Net Income was $21.7 million in Q3 2023, with the low at -$117.4 million in Q4 2025.
  • The 4-year median for Net Income is -$10.2 million (2021), against an average of -$23.1 million.
  • The sharpest annual moves came in 2022 and 2023: Net Income plunged 996066.21% in 2022, then soared 1028.2% in 2023.
  • Senti Biosciences Holdings' Net Income stood at -$33.6 million in 2021, then surged by 74.54% to -$8.5 million in 2022, then soared by 99.67% to -$28000.0 in 2023, then sank by 419032.14% to -$117.4 million in 2025.
  • Business Quant data shows SNTI's Net Income at -$117.4 million in Q4 2025, -$26.6 million in Q3 2025, and -$58.4 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 482.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -13.27 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 81.49 Mn
10 Senti Biosciences Holdings 12.06 Mn 12.06 Mn - -14.43 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -117.36 Mn
Sep 30, 2025 -26.59 Mn
Jun 30, 2025 -58.45 Mn
Mar 31, 2025 -21.55 Mn
Dec 31, 2023 -28,000.00
Sep 30, 2023 21.69 Mn
Jun 30, 2023 -4.45 Mn
Mar 31, 2023 -4.87 Mn
Dec 31, 2022 -8.55 Mn
Sep 30, 2022 -2.34 Mn
Jun 30, 2022 -82.14 Mn
Mar 31, 2022 -11.73 Mn
Dec 31, 2021 -33.57 Mn
Sep 30, 2021 -11.42 Mn
Jun 30, 2021 -9.00 Mn
Mar 31, 2021 -1,178.00