Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.38 -0.06 (-12.91%)
As of: Aug 21, 2026 · 2:25 PM EDT

Senti Biosciences Holdings (SNTI) EPS (Basic) (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly EPS (Basic) of -$5.22 for Q4 2025, down 655.29% quarter-over-quarter from -$0.69 in Q3 2025.

Senti Biosciences Holdings (SNTI) EPS (Basic) (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' EPS (Basic) history runs 5 years deep, the most recent figure standing at -$5.22 for Q4 2025.

  • In Q4 2025, EPS (Basic) changed N/A year-over-year to -$5.22; the TTM figure through Dec 2025 stood at -$7.31 (up 35.62% YoY), while the FY2025 annual figure was -$7.45, changed N/A from the prior year.
  • EPS (Basic) for Q4 2025 stood at -$5.22, down from -$0.69 in the prior quarter.
  • The five-year high for EPS (Basic) was $4.88 in Q3 2023, with the low at -$115.26 in Q4 2021.
  • The 5-year median for EPS (Basic) is -$2.45 (2024), against an average of -$11.03.
  • The sharpest annual moves came in 2022 and 2023: EPS (Basic) slumped 209924.29% in 2022, then soared 1006.3% in 2023.
  • Senti Biosciences Holdings' EPS (Basic) stood at -$115.26 in 2021, then jumped by 97.16% to -$3.27 in 2022, then surged by 99.81% to -$0.01 in 2023, then plunged by 99841.82% to -$6.31 in 2024, then gained by 17.23% to -$5.22 in 2025.
  • Business Quant data shows SNTI's EPS (Basic) at -$5.22 in Q4 2025, -$0.69 in Q3 2025, and -$0.56 in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Vertex Pharmaceuticals 138.90 Bn 131.05 Bn 2.84 Bn 4.34
2 Regeneron Pharmaceuticals 86.10 Bn 78.11 Bn 3.93 Bn 12.62
3 Argenx Se 65.56 Bn 60.37 Bn 1.37 Bn 7.59
4 Moderna 55.82 Bn 50.68 Bn 52.00 Mn -1.96
5 BeOne Medicines 42.14 Bn 37.04 Bn 1.53 Bn 2.12
6 Alnylam Pharmaceuticals 31.67 Bn 28.36 Bn 992.69 Mn 1.23
7 BioNTech SE 27.74 Bn 9.35 Bn 668.28 Mn -0.72
8 Insmed 27.53 Bn 26.37 Bn 358.27 Mn -0.06
9 Royalty Pharma 27.38 Bn 26.54 Bn - 0.18
10 Senti Biosciences Holdings 11.83 Mn 11.83 Mn - -0.46

Historic Data

Download Data
DateValue
Dec 31, 2025 -5.22
Sep 30, 2025 -0.69
Jun 30, 2025 -0.56
Mar 31, 2025 -1.41
Sep 30, 2024 -6.31
Jun 30, 2024 -2.45
Mar 31, 2024 -2.65
Dec 31, 2023 -0.01
Sep 30, 2023 4.88
Jun 30, 2023 -1.00
Mar 31, 2023 -1.11
Dec 31, 2022 -3.27
Sep 30, 2022 -0.54
Jun 30, 2022 -61.09
Mar 31, 2022 -4.95
Dec 31, 2021 -115.26
Sep 30, 2021 -3.88
Jun 30, 2021 -4.11
Mar 31, 2021 0.00