Senti Biosciences (SNTI) EBT (2021 - 2025)

Senti Biosciences' quarterly EBT came in at -$18.5 million in Q4 2025, down 16.33% year-on-year from -$22.2 million in Q4 2024, and down 10.47% quarter-over-quarter from -$16.8 million in Q3 2025.

Senti Biosciences has reported EBT for 5 years, with the latest figure at -$18.5 million in Q4 2025.

  • For the quarter ending Q4 2025, EBT fell 16.33% year-over-year to -$18.5 million; the trailing twelve-month figure through Dec 2025 stood at -$67.9 million (down 12.91% YoY), and the FY2025 full-year result was -$67.9 million, down 12.92% from the prior year.
  • EBT for Q4 2025 stood at -$18.5 million, down from -$16.8 million in the prior quarter.
  • The five-year high for EBT was -$1178.0 in Q1 2021, with the low at -$43.3 million in Q3 2023.
  • Average EBT over 5 years is -$15.3 million, with a median of -$15.4 million recorded in 2022.
  • Year-over-year, EBT slumped 997692.87% in 2022 and jumped 65.2% in 2024.
  • Tracing SNTI's EBT over 5 years: stood at -$3.9 million in 2021, then sank by 306.16% to -$15.7 million in 2022, then slipped by 16.63% to -$18.3 million in 2023, then advanced by 12.78% to -$15.9 million in 2024, then dropped by 16.33% to -$18.5 million in 2025.
  • The last three EBT figures came in at -$18.5 million (Q4 2025), -$16.8 million (Q3 2025), and -$16.5 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.60 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.31 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.18 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 831.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 221.65 Mn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -18.54 Mn
Sep 30, 2025 -16.78 Mn
Jun 30, 2025 -16.53 Mn
Mar 31, 2025 -16.00 Mn
Dec 31, 2024 -15.94 Mn
Sep 30, 2024 -15.07 Mn
Jun 30, 2024 -13.12 Mn
Mar 31, 2024 -15.97 Mn
Dec 31, 2023 -18.27 Mn
Sep 30, 2023 -43.29 Mn
Jun 30, 2023 -14.39 Mn
Mar 31, 2023 -13.90 Mn
Dec 31, 2022 -15.67 Mn
Sep 30, 2022 -14.21 Mn
Jun 30, 2022 -21.74 Mn
Mar 31, 2022 -11.75 Mn
Dec 31, 2021 -3.86 Mn
Sep 30, 2021 -11.42 Mn
Jun 30, 2021 -8.99 Mn
Mar 31, 2021 -1,178.00